BMP-signaling
Augmented BMPRIA-mediated BMP signaling in cranial neural crest lineage leads to cleft palate formation and delayed tooth differentiation.
... gain-of BMP signaling function model, in which a cleft palate formed, but the molars and lower incisors developed normally except an early fusion of upper incisors ...enhanced BMP activity in the ...
9
Reduced BMP signaling results in hindlimb fusion with lethal pelvic/urogenital organ aplasia: a new mouse model of sirenomelia.
... of BMP signaling is required to regulate distinct developmental ...between BMP genes during caudal ...of BMP signaling and can act both to promote and inhibit BMP ...
9
BMP signaling mediates effects of exercise on hippocampal neurogenesis and cognition in mice.
... of BMP signaling and niche properties produced such strong, bidirectional effects on tests requiring discrimination and integration of novel information suggest that BMP signaling plays a ...
22
Sfrp5 modulates both Wnt and BMP signaling and regulates gastrointestinal organogenesis [corrected] in the zebrafish, Danio rerio.
... Wnt signaling, especially of non-canonical Wnt signaling, result in similar molecular and phenotypic ...Wnt signaling affected gastrulation in similar ways [85] and in zebrafish, overexpression and ...
16
Regulation of extracellular matrix organization by BMP signaling in Caenorhabditis elegans.
... receptor signaling pathway or by altered accessibility of the drug to its ...DBL-1 signaling are resistant to the higher molecular weight drugs tested in this study, levamisole and ...
12
BRITER: a BMP responsive osteoblast reporter cell line.
... for BMP activity if pure BMP is ...than BMP signaling pathway may be perturbed, ...no BMP- responsive osteogenic cell line has been generated till date which has such an in-built ...
11
Bmp indicator mice reveal dynamic regulation of transcriptional response.
... conserved signaling circuit that is utilized throughout development, from the subdivision of tissue types during early embryogenesis to the formation of limbs and internal ...of Bmp signaling ...
13
Quinoline compound KM11073 enhances BMP-2-dependent osteogenic differentiation of C2C12 cells via activation of p38 signaling and exhibits in vivo bone forming activity.
... the BMP-2- stimulated induction of alkaline phosphatase (ALP), an early phase biomarker of osteoblast differentiation, in bi-potential mesenchymal progenitor C2C12 ...the BMP antagonist noggin, suggesting ...
13
J. Appl. Oral Sci. vol.20 número6
... Classical signaling pathway for BMPs begins with the binding of BMP to a dimeric complex of transmembrane serine-threonine kinase receptors, the type I and type II ...include BMP receptors (BMPRs) ...
8
A targeted glycan-related gene screen reveals heparan sulfate proteoglycan sulfation regulates WNT and BMP trans-synaptic signaling.
... and BMP intercellular signaling, Dally-like Protein and Syndecan, are differentially misregulated in the synaptomatrix of these ...and BMP (Glass Bottom Boat; Gbb) ligand abundance in the ...Wg ...
21
Analysis of the molecular interactions between Msx1 and other key players during mouse limb development
... the BMP signaling pathway, by testing their ability to interact with the PSmad1,5,8 protein complex, the intracellular transducer of the BMP signaling ...the BMP signaling ...
49
Patterning of the dorsal-ventral axis in echinoderms: insights into the evolution of the BMP-chordin signaling network.
... by BMP signaling has been studied, BMPs always act within the territory in which they are ...the BMP molecule being translocated to the dorsal side where it activates BMP ...the BMP ...
26
A feed-forward loop coupling extracellular BMP transport and morphogenesis in Drosophila wing.
... affects BMP signaling in the PCV ...in BMP signaling, mutant clones of cv-c c524 , a null allele of cv-c, were generated using the MARCM system ...Since BMP ligands are produced in the ...
11
Bone morphogenetic protein signaling protects against cerulein-induced pancreatic fibrosis.
... three BMP type II receptors (BMPR2, ActRIIa and ActRIIb) ...pancreatic BMP signaling existing in the heterozygous mice, which may account for the normal development of the ...
9
A multi-scale model of hepcidin promoter regulation reveals factors controlling systemic iron homeostasis.
... near-multiplicative signaling integration (fold-change over basal in response to co-stimulation equals the product of the mono-stimulation fold-changes) (Supplemental ...basal BMP signaling activity ...
13
BMP pathway regulation of and by macrophages.
... mutual signaling and receptor specificity, A7r5 vascular smooth muscle cells transfected with pBRE-Luc were co-cultured with either resting wild-type macrophages or stimulated wild-type macrophages (with LPS ...
12
A utilização das BMP-2 em estratégias de regeneração do tecido ósseo
... As BMP-2 são citocinas responsáveis por mediar processos de indução, formação e remodelação de osso no organismo. Estudaram-se então métodos para a utilização destas proteínas em técnicas de regeneração óssea para ...
35
Retroactive signaling in short signaling pathways.
... of signaling cascade is used as a paradigm or a model of signaling ...a signaling cascade consists of a succession of covalent modification cycles, whose classical representative example is the ...
13
Nuclear translocation of STAT3 by in vitro metreleptin administration causes lipolysis in human primary adipocytes
... metreleptin signaling in human primary adipocytes (hPA) metabolism, we extended previous observations by studying in vitro metreleptin signaling in cells from human adipose ...
7
The transcriptomics of glucocorticoid receptor signaling in developing zebrafish.
... glucocorticoid signaling in patterning the zebrafish hypothalamus is a very interesting finding, as the hypothalamus is the initial organizer for the stress response in vertebrates ...
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