Cell cycle control
Oxidative stress, genome lesions and signaling pathways in cell cycle control.
... OXIDATIVE STRESS, GENOME LESIONS AND SIGNALING PATHWAYS IN CELL CYCLE CONTROL. The generation of reactive oxygen species (ROS) may be both beneficial to cells, performing functions in intracellular ...
5
Cell cycle control and DNA damage response of conditionally immortalized urothelial cells.
... urothelial cell line is conditionally immortalized under permissive conditions, but restores cell cycle control under non-permissive ...B) Cell cycle analysis of ULTI cells under ...
11
Homeodomain transcription factor Meis1 is a critical regulator of adult bone marrow hematopoiesis.
... undergo cell-cycle entry without an increase in this compartment, suggesting that Meis1 regulates self-renewal capacity of HSCs but not their simple expansion or ...similar cell context-dependent ...
11
HDAC8, A Potential Therapeutic Target for the Treatment of Malignant Peripheral Nerve Sheath Tumors (MPNST).
... unchanged cell cycle progression in HeLa cells after HDAC8 inhibition using PCI-34051; a difference possibly due to cell type and ...in cell cycle ...S-phase cell cycle ...
12
Simulation of Swanson's literature-based discovery: anandamide treatment inhibits growth of gastric cancer cells in vitro and in silico.
... on cell cycle distribution of gastric cancer ...The cell cycle phase was analyzed with flow ...of cell cycle. The control cells were treated with ethanol ...The ...
11
KLF2--a negative regulator of pre-B cell clonal expansion and B cell activation.
... a cell with a functional mHC and, subsequently, in an enlargement of the antibody ...pre-B cell expansion after 2–5 rounds of proliferation ...B cell leukemia, as demonstrated in BLNK and BLNK/BTK- ...
8
Oudineta, Lior Pytowskia, Jean-Baptiste Bérardb, Elodie Nicolaub, Valérie Thiérya, Isabelle Lanneluca, Laureen Beaugearda, Grégoire Pruniera, Jackson Roberto Guedes Da Silva Almeidac, Laurent Picota, ∗
... melanoma cell line A2058 (Baudelet et ...melanoma cell lines (SP6.5 and C918) without impairing the cell viability of non cancer uveal melanocytes (Bi et ...melanoma cell line as a relevant ...
11
Antitumor Activity of Kielmeyera Coriacea Leaf Constituents in Experimental Melanoma, Tested in Vitro and in Vivo in Syngeneic Mice
... Presently, we show that the chloroform extract from leaves of K. coriacea have long-chain fatty compounds. The alkene 1-docosene, the alcohols 1-eicosanol, 1- docosanol and 1-hexacosanol, and the ketones 2- heptadecanone ...
8
Cell proliferation and migration are modulated by Cdk-1-phosphorylated endothelial-monocyte activating polypeptide II.
... during cell cycle phases, chemical synchronization and immunofluorescence using an N-terminal EMAP II antibody during G0, S, and G2M of cell cycle was ...of cell cycle (Figure 4A ...
10
Identification of Cell Cycle Dependent Interaction Partners of the Septins by Quantitative Mass Spectrometry.
... We used Shs1 as attachment site for the CCG module as in contrast to the other tested sep- tin subunits, Shs1-CCG looked indistinguishable from the GFP-labeled septins during the cell cycle. However, by ...
21
State of the Art in the Studies on Crotamine, a Cell Penetrating Peptide from South American Rattlesnake
... octaarginines. D-Tat 49–57 (RKKRRQRRR) and D- octaarginine (RRRRRRRR) and penetratin (RQIKIWFQNR- RMKWKK) are also highly cationic. In addition, penetratin and CyLoP-1 derived peptide 4 (CRWRWKCCKK) are rich in ...
10
Lactobacillus decelerates cervical epithelial cell cycle progression.
... GCT GAG GT-39; the CDKN1A reverse primer, 59-TGC CGC ATG GGT TCT GAC GG-39; the TUBA1A forward primer, 59- ACA TCG ACC GCC TAA GAG TCG C-3 9; and the TUBA1A reverse primer, 5 9-TGC ACT CAC GCA TGG TTG CTG-39. The ...
10
A hybrid model of mammalian cell cycle regulation.
... and cell division is regulated by a complex network of biochemical reactions that control the activities of a family of cyclin-dependent ...of cell cycle ...
10
Heterogenic final cell cycle by chicken retinal Lim1 horizontal progenitor cells leads to heteroploid cells with a remaining replicated genome.
... one cell having a double fluorescence signal (two spots). The Lim1+ cell is also shown as an animated rotation of the 3D reconstruction in the supporting ...a cell positioned in the ganglion ...
13
Meiotic recombination intermediates are resolved with minimal crossover formation during return-to-growth, an analogue of the mitotic cell cycle.
... mitotic cell cycle is less well understood, mainly due to low levels of inter-homolog ...mitotic cell cycle, we used a unique feature of Saccharomyces cerevisiae, return to growth (RTG), where ...
14
Cell-cycle inhibition by Helicobacter pylori L-asparaginase.
... programmed cell death ...some cell-types are auxotrophes. In fact, the cell-cycle block of cell clones, especially leukemic, exposed to this enzyme class has been previously described ...
11
In vitro effects of ellagic acid in C6 rat glioma cell cultures in terms of cytotoxicity and proliferation
... d. Preparation of three dimensional cul- tures for electron microscopic evaluation: In- oculation was done for three dimensional cultures in agar coated cell culture dishes. 500000 cells in 5 ml DMEM/F12 medium ...
7
Neuronal injury external to the retina rapidly activates retinal glia, followed by elevation of markers for cell cycle re-entry and death in retinal ganglion cells.
... RGC cell bodies reside in the retina and their fibers form the optic ...RGC cell bodies was apparent, glia had increased levels of phospho-Akt, phospho-S6, and phospho-ERK1/2; however, these signals were ...
14
Rising cyclin-CDK levels order cell cycle events.
... the control of an attenuated galactose-inducible (GALL) promoter ...overall cell size [21], so we used a histone H2B-mCherry fusion to mark the nucleus, and measured the mean YFP intensity within this mask ...
15
Modelling Cell Cycle using Different Levels of Representation
... We define an approach to model biological systems at different levels of representation. We con- sider the molecular level, in which organic molecules interact through biochemical reactions, as the lowest level of our ...
19