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CHROMOSOMAL INSTABILITY

Correlation of chromosomal instability, telomere length and telomere maintenance in microsatellite stable rectal cancer: a molecular subclass of rectal cancer.

Correlation of chromosomal instability, telomere length and telomere maintenance in microsatellite stable rectal cancer: a molecular subclass of rectal cancer.

... exhibiting chromosomal instability (CIN+) versus those with intact karyotype and chromosomal stability ...of chromosomal instability, rather than the microsatellite status, is the ...

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Mechanism of suppression of chromosomal instability by DNA polymerase POLQ.

Mechanism of suppression of chromosomal instability by DNA polymerase POLQ.

... Cells lacking Polq were analyzed for their ability to proliferate in culture. Two independent BMSC lines devoid of Polq expression proliferated at a rate comparable to a pair of wild-type control cells, the Polq BMSCs ...

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Telomere-mediated chromosomal instability triggers TLR4 induced inflammation and death in mice.

Telomere-mediated chromosomal instability triggers TLR4 induced inflammation and death in mice.

... between chromosomal instability and immune re- sponses, we have now established the obligatory role of toll-like ...chromosome instability in the cellular level stabilises the action of TLR4- induced ...

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Tumor environmental factors glucose deprivation and lactic acidosis induce mitotic chromosomal instability--an implication in aneuploid human tumors.

Tumor environmental factors glucose deprivation and lactic acidosis induce mitotic chromosomal instability--an implication in aneuploid human tumors.

... Mitotic chromosomal instability (CIN) plays important roles in tumor progression, but what causes CIN is incompletely understood. In general, tumor CIN arises from abnormal mitosis, which is caused by ...

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Allelic imbalance studies of chromosome 9 suggest major differences in chromosomal instability among nonmelanoma skin carcinomas

Allelic imbalance studies of chromosome 9 suggest major differences in chromosomal instability among nonmelanoma skin carcinomas

... microsatellite instability in chromosome ...controlling chromosomal stabil- ity in these two forms of cancer and demon- strates that basal cell carcinomas may be more genetically unstable than previously ...

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Orientador: Doutora Gaëlle Marteil, Instituto Gulbenkian de Ciência Co-orientador: Doutora Mónica Bettencourt-Dias Instituto Gulbenkian de Ciência

Orientador: Doutora Gaëlle Marteil, Instituto Gulbenkian de Ciência Co-orientador: Doutora Mónica Bettencourt-Dias Instituto Gulbenkian de Ciência

... cells. Mitotic chromosomal instability and cancer: mouse modelling of the human disease. Chromosomal instability and aneuploidy in cancer: from yeast to man. Oncogene-like induction of [r] ...

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Rev. Bras. Hematol. Hemoter.  vol.36 número3

Rev. Bras. Hematol. Hemoter. vol.36 número3

... Methods: A retrospective study was carried out of 21 candidates for cell therapy. After the isolation of bone marrow mononuclear cells by density gradient, mesenchymal stem cells were cultivated and expanded at least ...

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Genomic instability in newborn with short telomeres.

Genomic instability in newborn with short telomeres.

... A subgroup of 35 individuals from the population was selected in order to determine newborn individual genomic instability. This was achieved by performing a challenging experiment with MMC, where cord blood ...

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Beyond the chromosome: the prevalence of unique extra-chromosomal bacteriophages with integrated virulence genes in pathogenic Staphylococcus aureus.

Beyond the chromosome: the prevalence of unique extra-chromosomal bacteriophages with integrated virulence genes in pathogenic Staphylococcus aureus.

... FBU01 shares sequence homology to several phages, including S. aureus bacteriophage FNM3 (GenBank: DQ530361.1) contain- ing a region of 98% percent identity with a query coverage of 83%. FNM3 is a defective b-haemolysin ...

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Chromosomal organization and segregation in Pseudomonas aeruginosa.

Chromosomal organization and segregation in Pseudomonas aeruginosa.

... of chromosomal organization and segregation in a handful of bacteria has revealed surprising variety in the mechanisms mediating such fundamental ...20 chromosomal markers and several components of the ...

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Chromosomal Polymorphism in the Sporothrix schenckii Complex

Chromosomal Polymorphism in the Sporothrix schenckii Complex

... Variations in chromosome length are common in fungal strains, although the mechanism underlying chromosome length poly- morphisms remains unclear. Potential mechanisms include a recombination between repeated sequences ...

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M A T E R I A L E MÉTODOS

M A T E R I A L E MÉTODOS

... 1973 — Chromosomal polymorphism in the saltans group of Drosophila.. The saltans sub- group.[r] ...

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Chromosomal organization and phylogenetic relationships in Hypochaeris

Chromosomal organization and phylogenetic relationships in Hypochaeris

... Recently, fluorescent in situ hybridization (FISH) has been the method of choice for assigning DNA sequences to chromosomes. The technique is specially appropriated to understand the chromosomal organization and ...

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High Levels of Chromosomal Differentiation in Euchroma gigantea

High Levels of Chromosomal Differentiation in Euchroma gigantea

... the different karyotypes. The karyotypic evolution of Brazilian E. gigantea may have taken two directions, reduction in the diploid number of 2n = 36 to 24 through centric fusions or 2n = 24 to 36 due to ...

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FINANCIAL INSTABILITY, FINANCIAL DEVELOPMENT AND POVERTY

FINANCIAL INSTABILITY, FINANCIAL DEVELOPMENT AND POVERTY

... financial instability which accompanies financial development is is costly for the poor and reduces the positive effect of financial development on the reduction of ...

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Chromosomal inversion polymorphism in Drosophila mediopunctata

Chromosomal inversion polymorphism in Drosophila mediopunctata

... Chromosomal inversion polymorphism in species of Drosophila is one of the best studied systems in population genetics. Inversions have been used to study phylogenies, geographical clines, temporal cycles, meiotic ...

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Chromosomal polymorphism in Drosophila willistoni populations

Chromosomal polymorphism in Drosophila willistoni populations

... Studies of the genetic characteristics of marginal pop- ulations make impossible to test the idea that gene flow is a cohesive force that holds a species together and allows it to evolve as a unit. Such populations may ...

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Chromosomal characterization of Pseudonannolene strinatii (Spirostreptida, Pseudonannolenidae)

Chromosomal characterization of Pseudonannolene strinatii (Spirostreptida, Pseudonannolenidae)

... For chromosomal analysis, individuals were starved for one week and then injected with 0.1 ml of 0.08% colchicine. After approximately 16 hours (overnight), the specimens were dissected in order to extract the ...

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REFERENCIAÇÃO: INSTABILIDADE E INTERAÇÃO / Reference, instability and interaction

REFERENCIAÇÃO: INSTABILIDADE E INTERAÇÃO / Reference, instability and interaction

... Faz-se importante perceber, segundo Marcuschi (2005, p.60), os aspectos que se evidenciam na anáfora indireta: inexistência de expressão explícita antecedente ou subsequente [r] ...

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ON THE INSTABILITY OF THE RAILWAY VEHICLES

ON THE INSTABILITY OF THE RAILWAY VEHICLES

... Abstract. The railway vehicles have two sources of instability. The most common is the hunting induced by the reversed conic shape of the rolling surfaces of the wheels. The other one is related by the anomalous ...

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