Chromosomal rearrangements
Multiple chromosomal rearrangements structured the ancestral vertebrate Hox-bearing protochromosomes.
... two chromosomal crossover events occurred between the vertebrate protochromosomes bearing the core Hox paralogon genes, but are such chromosomal rearrangements likely? Several studies have shown that ...
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A familial Cri-du-Chat/5p deletion syndrome resulted from rare maternal complex chromosomal rearrangements (CCRs) and/or possible chromosome 5p chromothripsis.
... a chromosomal syndrome characterized by the characteristic features, including cat- like cry and chromosome 5p ...showing chromosomal rearrangements involving 5p, resulting from rare maternal complex ...
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Predominance of constitutional chromosomal rearrangements in human chromosomal fragile sites
... A higher number of deletions compared to duplications in CFSs was found (Figure 4) but not in non-FRs. These findings can be due to the differences in mechanisms of generation of these chromosomal ...
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Polymorphism of Sooty-fronted Spinetail (Synallaxis frontalis Aves: Furnariidae): Evidence of chromosomal rearrangements by pericentric inversion in autosomal macrochromosomes
... The Passeriformes is the most diverse and cytogenetically well-known clade of birds, comprising approximately 5,000 species. The sooty-fronted spinetail (Synallaxis frontalis Aves: Furnariidae) species, which belongs to ...
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Stimulation of gross chromosomal rearrangements by the human CEB1 and CEB25 minisatellites in Saccharomyces cerevisiae depends on G-quadruplexes or Cdc13.
... Chromosomal rearrangements are potentially detrimental for cell functions and are the source of genetic diseases and ...involving chromosomal rearrangements ...
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Expression changes of the ETS family of transcription factors associated with chromosomal rearrangements in breast cancer.
... Another mechanism for oncogene activation is translocation, which is the most common mechanism of origin of fusion genes, whose activity is different from the ones that originated them. Any badly repaired event that ...
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Molecular cytogenetic analyses reveal extensive chromosomal rearrangements and novel B chromosomes in Moenkhausia (Teleostei, Characidae)
... ferent populations of M. oligolepis. Morphologically distinct B chromosomes have been described in a range of Neotropi- cal fishes, in which microchromosomes are the most fre- quent type (Carvalho et al., 2008; Oliveira ...
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Chromosomal rearrangements and protein globularity changes in Mycobacterium tuberculosis isolates from cerebrospinal fluid
... large-scale rearrangements, short translocations, inversions, indels and nsSNPs in our CSF-derived strains, as well as protein globularity changes and orthologs of meningitis-associated genes previously reported ...
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Transposon domestication versus mutualism in ciliate genome rearrangements.
... A transposon rearranges its host’s genome when it moves from one genomic locus to another. When they invade coding or regulatory regions, transposons can alter gene expression. Furthermore, transposon-induced DNA ...
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Chromosomal evolution in Rattini (Muridae, Rodentia)
... chromosome rearrangements (fusions, fissions and pericentric inversions) have occurred within Rattini, the variation is somewhat muted when one takes each species/lineage separately into account ...of ...
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A genomewide screen for suppressors of Alu-mediated rearrangements reveals a role for PIF1.
... Here we report the systematic analysis of the complete set of yeast gene deletion mutants to identify genes required for preventing Alu-mediated aberrant homologous recombination events, providing a global view of these ...
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MLL leukemia-associated rearrangements in peripheral blood lymphocytes from healthy individuals
... or apoptosis, such as serum starvation or treatment with cy- tosine arabinoside (Stanulla et al., 1997; Betti et al., 2001; Vaughan et al., 2005). The activation of some components of the apoptotic process under these ...
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Comprehensive Analysis of Genome Rearrangements in Eight Human Malignant Tumor Tissues.
... Previous studies [6, 9–13] have detected an increased number of CNVs in human malignant tumors and found a functional correlation of CNVs with tumorigenesis. For example, Gratias et al. [9] reported small deletions in ...
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Dynamic 3D cell rearrangements guided by a fibronectin matrix underlie somitogenesis.
... The dynamic behavior of PSM cells suggests that they are continuously sensing and adjusting to the surroundings (other tissues and the ECM). Our results show that the inhibition of FN matrix assembly does not affect PSM ...
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Detection of genomic rearrangements in allopolyploids of the tribe Triticeae
... Plant HT9-15 showed a high number of structural rearrangements and numerical irregularities such as the presentation of few metaphase cells with an aneuploid chromosome number of 2n=40 and 2n=41. Once most of the ...
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Chromosomal characterization of Pseudonannolene strinatii (Spirostreptida, Pseudonannolenidae)
... For chromosomal analysis, individuals were starved for one week and then injected with 0.1 ml of 0.08% colchicine. After approximately 16 hours (overnight), the specimens were dissected in order to extract the ...
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Chromosomal Polymorphism in the Sporothrix schenckii Complex
... Variations in chromosome length are common in fungal strains, although the mechanism underlying chromosome length poly- morphisms remains unclear. Potential mechanisms include a recombination between repeated sequences ...
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Chromosomal imbalances are uncommon in chagasic megaesophagus
... No significant association was detected in CM group between mean copy number per cell of each DNA target tested and parameters such as age, gender and the life style factors tobacco smoking and alcoholism although the ...
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Fetal calcifications are associated with chromosomal abnormalities.
... of chromosomal abnormalities in the stillbirth group is that fetal chromosomal abnormalities is not as frequent after gestational week 22 compared with earlier in pregnancy, as the vast majority of fetuses ...
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Banding for Chromosomal Identification in Bivalves: A 20-year History
... the chromosomal pairs in the karyotype, they do not allow the individual identification of all chromosomal pairs, not allowing in consequence the establishment of precise ...
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