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contractile function

The small molecule Wnt signaling modulator ICG-001 improves contractile function in chronically infarcted rat myocardium.

The small molecule Wnt signaling modulator ICG-001 improves contractile function in chronically infarcted rat myocardium.

... Ejection fraction was measured angiographically 4 weeks after coronary occlusion. This method has been adapted in various studies for the assessment of myocardial contractile function in infarcted hearts ...

11

Left atrial size and contractile function in healthy dogs and dogs with chronic mitral valve disease

Left atrial size and contractile function in healthy dogs and dogs with chronic mitral valve disease

... the contractile force and thus overcome the increased left ventricular filling ...atrial contractile function (transmitral A wave peak velocity and VTI, atrial ejection fraction, and atrial force) at ...

9

Interaction between age and obesity on cardiomyocyte contractile function: role of leptin and stress signaling.

Interaction between age and obesity on cardiomyocyte contractile function: role of leptin and stress signaling.

... cardiomyocyte contractile elements and maintain cell viability for a prolonged period of time, which may unevenly alter the true in vivo cardiomyocyte mechanics and thus bias cardiomyocyte function from ...

15

Oleanolic acid: a novel cardioprotective agent that blunts hyperglycemia-induced contractile dysfunction.

Oleanolic acid: a novel cardioprotective agent that blunts hyperglycemia-induced contractile dysfunction.

... We initially investigated our hypothesis by exposing isolated rat hearts to ischemia-reperfusion and found a marked decline in contractile function under high glucose perfusion conditions (simulated acute ...

17

Studies of Membrane Fluidity and Heart Contractile Force in Trypanosoma cruzi Infected Mice

Studies of Membrane Fluidity and Heart Contractile Force in Trypanosoma cruzi Infected Mice

... Antibodies against different parasite components and other cardiac structures have been identified (Ferrari et al. 1995) and specific antibodies anti-cardiac β -adrenergic and muscarinic receptors (Borda & Sterin ...

6

Clinics  vol.68 número4

Clinics vol.68 número4

... METHODS: Male Wistar rats underwent an aerobic exercise training protocol for eight weeks. The rats were then assigned to sham surgery (SHAM), sedentary lifestyle and myocardial infarction or exercise training and ...

8

Complex regulation of PKCβ2 and PDK-1/AKT by ROCK2 in diabetic heart.

Complex regulation of PKCβ2 and PDK-1/AKT by ROCK2 in diabetic heart.

... Both acute and chronic inhibition of the RhoA-ROCK pathway improve the contractile function of the diabetic heart [8–10], and we have previously demonstrated that this results at least i[r] ...

13

Bacterial flagellin triggers cardiac innate immune responses and acute contractile dysfunction.

Bacterial flagellin triggers cardiac innate immune responses and acute contractile dysfunction.

... of contractile function during sepsis is the result of the concerted action of multiple microbial virulence factors, each promoting intracellular innate immune defense mechanisms by interacting with ...

13

MEF2C-MYOCD and Leiomodin1 Suppression by miRNA-214 Promotes Smooth Muscle Cell Phenotype Switching in Pulmonary Arterial Hypertension.

MEF2C-MYOCD and Leiomodin1 Suppression by miRNA-214 Promotes Smooth Muscle Cell Phenotype Switching in Pulmonary Arterial Hypertension.

... structure, function and tone of the pulmonary vascular bed depend characteristically on the contractility of the smooth muscle ...and contractile function of SMCs ...

19

Int. braz j urol.  vol.29 número2

Int. braz j urol. vol.29 número2

... The authors used sheep for studying because from an anatomical standpoint, these animals present a very clear distinction between the smooth and striated components of the external urethral sphincter. In this elegant ...

4

Arq. Bras. Cardiol.  vol.93 número1

Arq. Bras. Cardiol. vol.93 número1

... function can show an abnormal response of ventricular function to exercise. Left ventricular dysfunction during exercise is an important predictor of prognosis in chronic aortic regurgitation; however, this ...

6

B Citronellol, an alcoholic monoterpene with inhibitory properties on the contractility of rat trachea

B Citronellol, an alcoholic monoterpene with inhibitory properties on the contractility of rat trachea

... muscle contractile pathway under certain circumstances. Other contractile agents were used and more experimental details for each protocol are provided in the Results and Discussion ...

9

J. bras. pneumol.  vol.37 número4 en v37n4a19

J. bras. pneumol. vol.37 número4 en v37n4a19

... Six hours after admission, the patient developed cardiogenic shock. She was given large doses of catecholamines (dobutamine and noradrenalin), was submitted to endotracheal intubation, and required mechanical ...

3

Alcohol Dehydrogenase Protects against Endoplasmic Reticulum Stress-Induced Myocardial Contractile Dysfunction via Attenuation of Oxidative Stress and Autophagy: Role of PTEN-Akt-mTOR Signaling.

Alcohol Dehydrogenase Protects against Endoplasmic Reticulum Stress-Induced Myocardial Contractile Dysfunction via Attenuation of Oxidative Stress and Autophagy: Role of PTEN-Akt-mTOR Signaling.

... main function of Atg4 is to cleave LC3 to LC3-I, among which Atg4B is the most efficient isoform ...good function of autophagy and autophagy flux ...

19

Arq. Bras. Cardiol.  vol.88 número1 en a29v88n1

Arq. Bras. Cardiol. vol.88 número1 en a29v88n1

... the contractile apparatus through the crosstalk that signals engagement between crosstalk receptors with the three families of G-proteins, especially stimulatory (Gs), inhibitory (Gi), and Gq/11 proteins, uses ...

6

Pulmonary Lymphangioleiomyomatosis: A Rare Case

Pulmonary Lymphangioleiomyomatosis: A Rare Case

... for contractile proteins (smooth muscle actin and desmin), the melanocytic marker HMB-45 (Figure 4), estrogen receptor (ER), progesterone receptor (PR), and CD56 in the LAM ...

4

Contractile profile of esophageal and gastric fundus strips in experimental doxorubicin-induced esophageal atresia

Contractile profile of esophageal and gastric fundus strips in experimental doxorubicin-induced esophageal atresia

... In the present study, the muscarinic agonist CCh elicited concentration-dependent contraction in esopha- geal strips, even in tissues from the DOXO group. However, esophageal strips of animals treated with DOXO ...

7

Rendering molecular surfaces as implicit surfaces on GPUs

Rendering molecular surfaces as implicit surfaces on GPUs

... column function (inverse squared), when compared with the two previously an- alyzed functions, is the fastest to compute Connolly ...this function all the atoms contribute to the modeling of a surface, and ...

75

Fibrillar organization in tendons: A pattern revealed by percolation characteristics of the respective geometric network

Fibrillar organization in tendons: A pattern revealed by percolation characteristics of the respective geometric network

... In this work we delineate a network approach for studying the tendon organization (system composed of interconnected fibrils) that could contribute to a better understanding of its biomechanical responses. Relative ...

16

Braz. J. Cardiovasc. Surg.  vol.24 número1 en v24n1a20

Braz. J. Cardiovasc. Surg. vol.24 número1 en v24n1a20

... tract, left ventricular myocardium with spongiform appearance (Figure 1), left ventricular contractile dysfunction of significant degree with an ejection fraction of 33.8% and mild mitra[r] ...

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