Er stress
ER stress in Parkinson’s disease
... I ER transmembrane protein kinase with a luminal domain and a cytoplasmic domain that has kinase ...Upon ER stress, BIP releases the luminal domain of PERK, which then dimerizes and ...
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Morbillivirus glycoprotein expression induces ER stress, alters Ca2+ homeostasis and results in the release of vasostatin.
... an ER stress, characterized by increased expression of the ER resident chaperon calnexin and the proapoptotic transcription factor CHOP/GADD ...another ER resident chaperon critically involved ...
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HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction.
... a cellular context other mechanisms such as altering the binding of other regulatory proteins (BAX, BAK, BI-1, AIP1, and RACK) to IRE1a are also involved. Previous reports and our data collectively support a model in ...
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Disruption of microRNA biogenesis confers resistance to ER stress-induced cell death upstream of the mitochondrion.
... of ER stress-induced cell death pathways. ER stress-induced cell death has previously been reported to signal through the mitochondrial or the intrinsic cell death pathway ...
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Gliadin peptides induce tissue transglutaminase activation and ER-stress through Ca2+ mobilization in Caco-2 cells.
... We carried out the present study to determine the effect of gliadin peptides on Ca 2+ homeostasis in the attempt to gain additional insights into the possible role exerted by gliadin peptides in the molecular mechanisms ...
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XBP1-Independent UPR Pathways Suppress C/EBP-β Mediated Chondrocyte Differentiation in ER-Stress Related Skeletal Disease.
... during ER stress may also influence gene expression by degrading transcripts encoding membrane-bound and secreted proteins through regulated IRE1 dependent decay (RIDD) [25] and promote apoptosis via ...
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Efects of açai on oxidative stress, ER stress, and infammationrelated parameters in mice with high fat diet-fed induced NAFLD.
... Real-time quantitative reverse transcription polymerase chain reaction (qRT-PCR) assay of ER stress in the liver. Total RNA was isolated from liver using the RNAgents Total RNA Isolation System (Z3105; ...
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Dietary Fish Oil Inhibits Pro-Inflammatory and ER Stress Signalling Pathways in the Liver of Sows during Lactation.
... of stress sig- naling pathways like the endoplasmic reticulum (ER) stress-induced unfolded protein response (UPR), both of which impair animal´s health and ...Whether ER stress-induced ...
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Precursor of advanced glycation end products mediates ER-stress-induced caspase-3 activation of human dermal fibroblasts through NAD(P)H oxidase 4.
... initial stages of wound healing, chronic activation of ROS have been shown to be stressors on the cell leading to apoptosis [38,54]. ROS have been shown to induce apoptosis through many pathways, one of which includes ...
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Chronic Insulin Exposure Induces ER Stress and Lipid Body Accumulation in Mast Cells at the Expense of Their Secretory Degranulation Response.
... were ER reprogramming and ER stress, analogous to observations in the obese hepatocyte and ...lipidome, ER status and pro-inflammatory ...
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Ubiquitin fold modifier 1 (UFM1) and its target UFBP1 protect pancreatic beta cells from ER stress-induced apoptosis.
... thapsigargin) decreased the abundance of conjugates, while a decrease in protein load with the translational inhibitor cyclohex- imide increased UFM1-UFBP1 conjugation. One possible inter- pretation is that UFM1-UFBP1 ...
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IRE1 phosphatase PP2Ce regulates adaptive ER stress response in the postpartum mammary gland.
... elevated stress-kinase signaling upon ER stressor stimulation [25], stress kinases were significantly induced in postpartum PP2Ce KO mammary gland compared to WT controls (Figure ...pathological ...
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Induction of ER stress in macrophages of tuberculosis granulomas.
... that ER stress was induced in mouse granulomas during Mtb ...the ER stress pathway was also activated in human granulomas from the lungs of TB ...the ER stress response and ...
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Guanabenz interferes with ER stress and exerts protective effects in cardiac myocytes.
... ER stress is increasingly recognized as a contributor to the pathophysiology of cardiovascular diseases, suggesting therapeutic interventions in its mechanisms as a new target for drug ...cellular ...
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Evaluation of ER stress induced by DNFB in Dendritic cells
... induce ER stress (BFA, Tunicamycin and thapsigargin), also activate the NLRP3 inflammasome in human and murine macrophages ...that ER stress causes activation of the NLRP3 inflammasome, with ...
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A novel proteasome inhibitor acting in mitochondrial dysfunction, ER stress and ROS production
... the ER-stress mediated apoptotic pathway [23–25]. ER organ- elle is involved in the synthesis, structural modification and transport of proteins and lipids ...in ER do not present a correct ...
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Contribution of ER stress to tumor immunosuppressive microenvironment
... that ER stress- apoptotic pathway could be activated (reviewed in ...proteins. ER stress is triggered by a hampering and impairment of proteasomal system, leading to an accumulation of these ...
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Transcriptional profiling reveals overlap between ER- and osmotic-stress responses in soybean
... the ER-stress response, the activation of this turnover mechanism has been observed in genome-wide analyses of Arabidopsis treated with inducers of ER stress and in a transcript-profiling ...
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Tunable green to red ZrO2:Er nanophosphors
... the Er 3+ ions in the ZrO 2 lattice was achieved as observed by ...conversion Er 3+ luminescence showed that using high and low energy photons as excitation, the domi- nant visible luminescence of the ...
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O stress ocupacional : As fontes de stress e suas associações
... de stress, Desenvolvimento de Carreira, Cooper (1988; ...de stress, particularmente nas organizações que enfatizam o relacionamento entre o desenvolvimento de carreira e a competência e valor do ...
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