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Extracellular matrix

Sporothrix schenckii to several extracellular matrix proteins

Sporothrix schenckii to several extracellular matrix proteins

... patients and alcoholics, the pulmonary and articular forms of sporotrichosis are the most frequent clini- cal manifestations (5,26). This fungus was also recently isolated from aqueous humor (27). Since this apparent ...

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Degenerated human intervertebral discs contain autoantibodies against extracellular matrix proteins

Degenerated human intervertebral discs contain autoantibodies against extracellular matrix proteins

... To identify if antibodies found in human degenerated IVDs, recognise proteins of the disc, we spotted on nitrocellulose membranes, proteins extracts from healthy bovine discs (bovine AF outer, AF inner and NP), along ...

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Exploring the role of proteolysis in Extracellular Matrix remodeling: Links to Chronic Obstructive Pulmonary Disease and Lung Cancer

Exploring the role of proteolysis in Extracellular Matrix remodeling: Links to Chronic Obstructive Pulmonary Disease and Lung Cancer

... Chronic obstructive pulmonary disease (COPD) and lung cancer (LC) are two complex disorders, currently representing the 4th cause of death and the most lethal cancer in Western countries, respectively. A mechanistic link ...

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The extracellular matrix provides directional cues for neuronal migration during cerebellar development

The extracellular matrix provides directional cues for neuronal migration during cerebellar development

... development. Extracellular matrix compo- nents play important roles in these processes, and interactions be- tween neurons and extracellular matrix are fundamental for the nor- mal development ...

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Effect of photodynamic therapy on the extracellular matrix and associated components

Effect of photodynamic therapy on the extracellular matrix and associated components

... proliferation, matrix assembly, proteases and inhibitors, among ...the extracellular matrix ...collagen matrix changes, including cross-linking. The extracellular matrix is vital ...

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Regulation of extracellular matrix organization by BMP signaling in Caenorhabditis elegans.

Regulation of extracellular matrix organization by BMP signaling in Caenorhabditis elegans.

... in extracellular matrix deposition and patterning, like many mammalian BMP phenotypes? Based on the observations that (1) the cuticle-secreting tissue contributes to the DBL-1-mediated body size phenotype ...

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Alterations in proteins of bone marrow extracellular matrix in undernourished mice

Alterations in proteins of bone marrow extracellular matrix in undernourished mice

... The objective of the present study was to determine the effect of protein malnutrition on the glycoprotein content of bone marrow extracellular matrix (ECM). Two-month-old male Swiss mice were submitted to ...

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Development of hyaluronic acid, dextrin and extracellular matrix hydrogels for cell expansion

Development of hyaluronic acid, dextrin and extracellular matrix hydrogels for cell expansion

... The aim of this project is to develop a new hydrogel made of Dextrin (Dex), Hyaluronic acid (HA) and Extracellular matrix (ECM) from Small Intestine Submucosa (SIS), using different types of HA, mixed ...

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The extracellular matrix of the lung and its role in edema formation

The extracellular matrix of the lung and its role in edema formation

... The extracellular matrix is composed of a three-dimensional fiber mesh filled with different macromolecules such as: collagen (mainly type I and III), elastin, glycosaminoglycans, and ...the ...

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Extracellular Matrix Stiffness Regulates Osteogenic Differentiation through MAPK Activation.

Extracellular Matrix Stiffness Regulates Osteogenic Differentiation through MAPK Activation.

... the extracellular matrix (ECM) through activation of intracellular signaling ...hydrogel matrix stimu- lates osteogenic differentiation concomitant with increased nuclear localization of TAZ, but ...

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Extracellular matrix formation enhances the ability of Streptococcus pneumoniae to cause invasive disease.

Extracellular matrix formation enhances the ability of Streptococcus pneumoniae to cause invasive disease.

... sticky matrix on the mucosal surface, although not all pneumococcal serotypes are able to invade the host and cause disease ...form matrix is an exclusive feature of the opaque variant and that this ...

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Regulation of pituitary hormones and cell proliferation by components of the extracellular matrix

Regulation of pituitary hormones and cell proliferation by components of the extracellular matrix

... The extracellular matrix is a three-dimensional network of proteins, glycosaminoglycans and other ...The extracellular matrix conveys signals through membrane receptors called integrins and ...

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Role of the extracellular matrix in variations of invasive pathways in lung cancers

Role of the extracellular matrix in variations of invasive pathways in lung cancers

... as extracellular matrix, ECM) for growth, invasion, and metastasis, ongoing studies are currently validating other ...cellular matrix rich in HA occurs after the matrix is degraded into ...

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Adaptation to High Grain Diets Proceeds Through Minimal Immune System Stimulation and Differences in Extracellular Matrix Protein Expression in A Model of Subacute Ruminal Acidosis in Non-lactating Dairy Cows

Adaptation to High Grain Diets Proceeds Through Minimal Immune System Stimulation and Differences in Extracellular Matrix Protein Expression in A Model of Subacute Ruminal Acidosis in Non-lactating Dairy Cows

... to matrix remodeling (Han et ...the extracellular matrix upon which the epithelium ...the matrix proteins, cytokines and members of the LPS- mediated TLR4 signal cascade that were seen in a ...

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miRNA-29c suppresses lung cancer cell adhesion to extracellular matrix and metastasis by targeting integrin β1 and matrix metalloproteinase2 (MMP2).

miRNA-29c suppresses lung cancer cell adhesion to extracellular matrix and metastasis by targeting integrin β1 and matrix metalloproteinase2 (MMP2).

... Cell adhesion to the ECM is mediated via integrins, the principle cell surface adhesion receptors. Integrins transduce intracellular signals across the plasma membrane, thereby regulating the proliferation, migration and ...

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Functions of the extracellular matrix and matrix degrading proteases during tumor progression

Functions of the extracellular matrix and matrix degrading proteases during tumor progression

... with extracellular matrices are important to patho- logical changes that occur during cell transformation and tumorigen- ...Several extracellular matrix proteins including fibronectin, throm- ...

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Streptococcus mutans-derived extracellular matrix in cariogenic oral biofilms

Streptococcus mutans-derived extracellular matrix in cariogenic oral biofilms

... of extracellular polymeric substances including exopolysaccharides (EPS), eDNA, and lipoteichoic acid ...diffusion-limiting matrix that protects embedded bacteria. The EPS-rich matrix provides ...

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Extracellular matrix and angiogenic factors in hematological diseases

Extracellular matrix and angiogenic factors in hematological diseases

... and extracellular matrix (ECM), in particular fibronectin (FN) that has been found increased in solid tumors, may be responsible for BM disease progression, but its precise role in this context has been ...

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Collagens and proteoglycans of the corneal extracellular matrix

Collagens and proteoglycans of the corneal extracellular matrix

... The quantitative and qualitative patterns of proteoglycan synthesis, and possibly of collagen fibril deposition, change when the cornea is submitted to injuries, such as epi- thelial debridement (36,58) and laser refrac- ...

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Extracellular Matrix Molecular Remodeling in Human Liver Fibrosis Evolution.

Extracellular Matrix Molecular Remodeling in Human Liver Fibrosis Evolution.

... To investigate the effects of decellularization protocol on the extracellular matrix network, his- tological investigations were performed. Hematoxylin/eosin and trichrome stain highlighted that no nuclei ...

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