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Extracellular Vesicles (EVs)

Deep sequencing analysis reveals distinctive non-coding RNAs when comparing tumor multidrug-resistant cells and extracellular vesicles with drug-sensitive counterparts

Deep sequencing analysis reveals distinctive non-coding RNAs when comparing tumor multidrug-resistant cells and extracellular vesicles with drug-sensitive counterparts

... that extracellular vesicles (EVs) participate in the communication between MDR cells and drug-sensitive counterparts, promoting dissemination of the MDR ...

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Extracellular Vesicles from Vascular Endothelial Cells Promote Survival, Proliferation and Motility of Oligodendrocyte Precursor Cells.

Extracellular Vesicles from Vascular Endothelial Cells Promote Survival, Proliferation and Motility of Oligodendrocyte Precursor Cells.

... We previously examined the effect of brain microvascular endothelial cell (MVEC) trans- plantation on rat white matter infarction, and found that MVEC transplantation promoted remyelination of demyelinated axons in the ...

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Circular RNAs Co-Precipitate with Extracellular Vesicles: A Possible Mechanism for circRNA Clearance.

Circular RNAs Co-Precipitate with Extracellular Vesicles: A Possible Mechanism for circRNA Clearance.

... While much attention has been focused on circRNA expression and biogenesis, very little is known about the metabolism of these molecules within the cell. Given their high degree of sta- bility, and their presumed ...

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On-chip immunoelectrophoresis of extracellular vesicles released from human breast cancer cells.

On-chip immunoelectrophoresis of extracellular vesicles released from human breast cancer cells.

... Extracellular vesicles (EVs) including exosomes and microvesicles have attracted consider- able attention in the fields of cell biology and ...individual vesicles are ...

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An important role of α-hemolysin in extracellular vesicles on the development of atopic dermatitis induced by Staphylococcus aureus.

An important role of α-hemolysin in extracellular vesicles on the development of atopic dermatitis induced by Staphylococcus aureus.

... Skin barrier disruption and dermal inflammation are key phenotypes of atopic dermatitis (AD). Staphylococcus aureus secretes extracellular vesicles (EVs), which are involved in AD pathogenesis. Here, we ...

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Structure and function of ABCG2-rich extracellular vesicles mediating multidrug resistance.

Structure and function of ABCG2-rich extracellular vesicles mediating multidrug resistance.

... The frequent emergence of drug resistance phenomena to structurally and functionally unrelated anticancer drugs known as multidrug resistance (MDR) continues to be a major impediment to curative cancer chemotherapy ...

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Clinical application of extracellular vesicles in vascular calcification

Clinical application of extracellular vesicles in vascular calcification

... Extracellular vesicles carry multiple types of molecules including proteins and nucleic acids, and these cargoes are more stable than they would be if exposed to body fluids, particularly in the case of ...

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Recovery of extracellular vesicles from human breast milk is influenced by sample collection and vesicle isolation procedures

Recovery of extracellular vesicles from human breast milk is influenced by sample collection and vesicle isolation procedures

... Extracellular vesicles (EV) in breast milk carry immune relevant proteins and could play an important role in the instruction of the neonatal immune ...

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The Pathogenic Fungus Paracoccidioides brasiliensis Exports Extracellular Vesicles Containing Highly Immunogenic alpha-Galactosyl Epitopes

The Pathogenic Fungus Paracoccidioides brasiliensis Exports Extracellular Vesicles Containing Highly Immunogenic alpha-Galactosyl Epitopes

... of extracellular vesicles in ...brasiliensis vesicles in vivo and the differences in contents that could account for distinct disease outcomes depending on the isolate are sub- jects to be ...by ...

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Lipidomic Analysis of Extracellular Vesicles from the Pathogenic Phase of Paracoccidioides brasiliensis

Lipidomic Analysis of Extracellular Vesicles from the Pathogenic Phase of Paracoccidioides brasiliensis

... brasiliensis extracellular vesicles, namely, Hex-C18:0-OH/d19:2-Cer and ...in vesicles is a glucosylceramide (GlcCer), although we have not determined the hexose ...brasiliensis extracellular ...

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EXTRACELLULAR VESICLES: CLASSIFICATION, FUNCTIONS AND CLINICAL RELEVANCE

EXTRACELLULAR VESICLES: CLASSIFICATION, FUNCTIONS AND CLINICAL RELEVANCE

... fact that microcells density and composition are understudied, and allowed diameter range of microparticles includes exosome diameter (30–100 nm), exosomes and microvesicles can be combined into one type. Membrane ...

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Characterization of the small RNA content of Trypanosoma cruzi extracellular vesicles

Characterization of the small RNA content of Trypanosoma cruzi extracellular vesicles

... secreted vesicles can be used to mediate intercellular communication processes by transferring various bioactive molecules, including mRNAs and ...lular vesicles contain RNA molecules and performed a deep ...

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Is the proteome of bronchoalveolar lavage extracellular vesicles a marker of advanced lung cancer?

Is the proteome of bronchoalveolar lavage extracellular vesicles a marker of advanced lung cancer?

... large extracellular vehicles (EVs) proteomes reveal aberrant protein expression in paracrine signaling mechanisms in cancer initiation and ...lavage extracellular vesicle samples which were analyzed by ...

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Extacellular vesicles at ecmo and trauma patients

Extacellular vesicles at ecmo and trauma patients

... of Extracellular Vesicles 2018 (MISEV2018) recognizes that, despite the effort to achieve universal subtype-specific markers of EVs, this goal is currently not possible as the results originate from studies ...

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Surface glycosylation profiles of urine extracellular vesicles.

Surface glycosylation profiles of urine extracellular vesicles.

... SP-DilC18(3) ranged from approximately 0.2 to 0.5 mg/mL based on Bradford estimation of protein content. This range gave the greatest signal-to-noise advantage and minimized spurious artifacts likely caused by the ...

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A Local Delivery System for Extracellular Vesicles to Promote Tissue Regeneration

A Local Delivery System for Extracellular Vesicles to Promote Tissue Regeneration

... , discussed above, EV injected intravenously, could reach the mouse brain, resulting in specific gene knockdown [49]. In further studies, MSC-derived EV injected in the tail vein were capable of improving animal ...

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A prospective highlight on exosomal nanoshuttles and cancer immunotherapy and vaccination

A prospective highlight on exosomal nanoshuttles and cancer immunotherapy and vaccination

... that cancer-originated EVs display marked ability to elicit a rapid tissue growth, while other extracellular vesicles (e.g., DEXOs) can impose tumor suppressor potentials. Thus, it seems that the vesicular ...

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Toward the isolation of exosomes by flow cytometry

Toward the isolation of exosomes by flow cytometry

... of extracellular vesicles divide them in three main classes: exosomes, microvesicles/microparticles/ectosomes and apoptotic ...intraluminal vesicles (ILVs). These intraluminal vesicles contain ...

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Preliminary studies on the use of exosomes as dendrimer carriers

Preliminary studies on the use of exosomes as dendrimer carriers

... of extracellular vesicles as ...of extracellular vesicles and, certainly, will serve as a basis for the development of future studies in ...

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Challenges and perspectives to enhance cattle production via in vitro techniques: focus on epigenetics and cell-secreted vesicles

Challenges and perspectives to enhance cattle production via in vitro techniques: focus on epigenetics and cell-secreted vesicles

... Extracellular vesicles are present in different body fluids including seminal plasma, ovarian follicular fluid and uterine fluid (TANNETTA et ...secreted vesicles containing bioactive molecules such ...

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