Galectin-1
Deregulation of Annexin-A1 and Galectin-1 Expression in Precancerous Gastric Lesions: Intestinal Metaplasia and Gastric Ulcer
... Objective. Annexin-A1 (ANXA1/AnxA1) and galectin-1 (LGALS1/Gal-1) are mediators that play an important role in the inlammatory response and are also associated with carcinogenesis. We investigated ...
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Endothelial galectin-1 binds to specific glycans on nipah virus fusion protein and inhibits maturation, mobility, and function to block syncytia formation.
... that galectin-1 reduces NiV-F mediated fusion of endothelial cells, and that endogenous galectin-1 in endothelial cells is sufficient to inhibit syncytia ...formation. Galectin-1 ...
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Galectin-1, an alternative signal for T cell death, is increased in activated macrophages
... of galectin-1 suggested participation in the regulation of the immune ...for galectin-1 as an alternative signal in the generation of T cell ...in galectin research in the context of ...
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Expression of annexin-A1 and galectin-1 anti-inflammatory proteins and mRNA in chronic gastritis and gastric cancer
... and galectin-1 have been associated with tumor ...and galectin-1 (LGALS1/Gal-1) in an inlammatory gastric lesion as chronic gastritis (CG) and gastric adenocarcinoma (GA) and its ...
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Effect of exogenous galectin-1 on leukocyte migration: modulation of cytokine levels and adhesion molecules
... Abstract: The effect of exogenous Gal-1 on cellular response and adhesion molecule expression was investigated in a classical model of acute inflammation induced by zymosan. C57BL6 mice, treated or not with human ...
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Galectins: a key intersection between glycobiology and immunology
... of galectin-3 cDNA into leukemia T cells conferred resistance to ap- optosis induced by Fas ligation and stauro- sporine ...interest, galectin- 3 showed a significant sequence similarity to Bcl-2, mainly ...
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ROLE OF GALECTIN-3 IN CARCINOGENESIS AND METASTASIS OF CANINE MALIGNANT MAMMARY TUMOURS
... [43]. Galectin-1 and -3, the most studied galectins, are involved in normal cell adhesion, migration and tissue remodelling during mammal development and regeneration processes ...specific galectin ...
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Therapy of experimental NASH and fibrosis with galectin inhibitors.
... among galectin proteins [31], but in contrast to other galectin proteins, it has a long N-terminal domain that is involved in forming multimers ...example, galectin-1 and galectin-3 ...
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The Eons of Chaos and Hades
... We suggest two Chaotian eras, each era with two periods (Fig. 1). The Eochaotian begins when the Solar Nebula be- came a closed system with respect to the rest of the giant molecular cloud and encompasses the ...
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Urachal Carcinoma: Imaging Findings
... Orbital MRI showed nodular enlargement of the bilateral multiple EOMs, including the right superior oblique muscle, lateral rectus and inferior rectus, and the left lateral and medial rectus. The enlarged EOMs exhibited ...
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Decreased galectin-9 and increased Tim-3 expression are related to poor prognosis in gastric cancer.
... Tim-3 is a powerful immunoinhibitory molecule involved in immune tolerance, and autoimmune responses. The mechanisms for regulating Tim-3 expression in tumor cells are not yet fully understood. Wiener et al reported that ...
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Lack of galectin-3 disturbs mesenteric lymph node homeostasis and B cell niches in the course of Schistosoma mansoni infection.
... with galectin-3 and elicit an intense humoral ...chronically-infected galectin-3 -/- mice exhibited a significant reduced amount of macrophages and B lymphocytes followed by drastic histological changes in ...
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Modulation of ocular surface glycocalyx barrier function by a galectin-3 N-terminal deletion mutant and membrane-anchored synthetic glycopolymers.
... bind galectin-3, did not enhance barrier function in our three-dimensional culture system; in fact, the regions of rose bengal uptake detected were similar to those of control ...for galectin-3 binding in ...
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The CCAAT/enhancer-binding protein beta-2 isoform (CEBPβ-2) upregulates galectin-7 expression in human breast cancer cells.
... for 1 h and subsequently blotted overnight at 4 uC with primary antibodies: rabbit anti-C/ EBPb polyclonal antibody (1:1000; sc-150 (C-19) Santa-Cruz Biotechnology, Santa Cruz, CA) and mouse anti-b-actin ...
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Overexpression of ezrin and galectin-3 as predictors of poor prognosis of cervical cancer
... (8). Galectin-3 belongs to the lectin family, a galactosidase binding protein with chimera ...of galectin-3 is closely related to the development of many human tumors, such as large-cell lymphoma, ...
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Book Review: Long Live Nature via Nurture!
... Ridley explains easily that genes are not puppet masters pulling the strings of our behavior (a common misunderstanding), but are puppets at the mercy of our behavior. Instinct is not[r] ...
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SOME MACROASPECTS OF FDI IN ROMANIA
... The paper studies the macroeconomic aspects and influence of FDI on banking sector, foreign external debt on medium and long term, labour market and relevant mac[r] ...
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Fibrosarcoma of the urinary bladder in a cat
... echogenicity (Figure 2a); mild bilateral pyelectasia (1 mm) was also detected. The cat was sedated, and the urethra was catheterised and the urinary bladder dis- tended with sterile 0.9% saline solution for better ...
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Marked cytoreduction of a lymphocyte-rich mediastinal thymoma with neoadjuvant chemotherapy in a cat
... The marked reduction in size of the thymoma in this case following neoadjuvant chemotherapy was unusual and therefore unexpected. As an optimal chemothera- peutic protocol for thymoma in dogs and cats has not been ...
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Concept Analysis as Empirical Method
... In the NRC-Handelsblad of 16 May 1998, Thijs Goldschmidt (social scientist) pleaded for a long-term behavioral-biological research project into bullying behavior in the schoolyard, whil[r] ...
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