γδ T cells
Decrease of perforin positive CD3+γδ-T cells in patients with obstructive sleep disordered breathing
... killer T cells (iNKT) are reduced in OSA patients ...NKT cells are important for the anti-tumor response, Gaoatswe and colleagues suggested their results might contribute to explain the possible ...
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Intraepithelial γδ T cells remain increased in the duodenum of AIDS patients despite antiretroviral treatment.
... cd T cells sometimes follows that of ab T cells, and the cd T cells may mainly contribute to immune regulation and tissue repair ...host cells has fuelled the view that cd ...
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γδ T cells are required for pulmonary IL-17A expression after ozone exposure in mice: role of TNFα.
... [18]. Cells were stained using the following antibodies: Alexa Fluor 647 anti- IL-17A (clone: ...gates. Cells were visualized using a Canto II (BD Biosciences) and the data was analyzed using Flowjo (Tree ...
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Circulating natural killer and γδ T cells decrease soon after infection of rhesus macaques with lymphocytic choriomeningitis virus
... NK cells have little influence on vi- rus loads in murine LCMV infections first came from the Welsh ...NK cells by cyclophosphamide (Biron et ...NK cells into 5-day-old mice with low NK cell activity ...
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Identification of a panel of ten cell surface protein antigens associated with immunotargeting of leukemias and lymphomas by peripheral blood γδ T cells
... Figure 2. Comparison of gene expression in tumor cell lines suscep- tible or resistant to γδ-PBL cytotoxicity. Bioinformatics analyses of cDNA microarray comparisons between the Burkitt’s lymphomas DAUDI and RAJI; ...
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γδ T cells are involved in acute HIV infection and associated with AIDS progression.
... cd T cells produce interleukin 17 (IL-17), interferon gamma (IFN-c), and other secreted protein factors after activation ...cd T cells are involved in the recruitment of neutrophils in ...
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Murine and bovine γδ T cells enhance innate immunity against Brucella abortus infections.
... spleen cells were stained with fluorochrome-conjugated or biotinylated mAbs (Becton Dickinson or eBioscience): anti-CD4 (clone L34T4), anti-CD8 (clone 853- ...GL3); cells were then fixed with 2% ...
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Obesity impairs γδ T cell homeostasis and antiviral function in humans.
... Vγ9Vδ2 T cell numbers, reduced IL-2Ra (CD25) expression, sensi- tivity to apoptosis, and accelerated terminal differentiation suggest that γδ T cells are lacking signals required for ...
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Mecanismos moleculares de ativação das células T γδ humanas na sua interação com células tumorais
... - γδ T cell activation, proliferation, Th1 cytokine secretion and anti-tumor cytotoxicity - are strictly dependent on Erk- and Akt-mediated signal ...the γδ TCR, and is capable of doing so at minimal ...
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Crosstalk between immunosuppressive myeloid and effector lymphoid cells in the tumour microenvironment
... NKT, γδ T cells) that are able to recognize developing tumours and constitute an early source of ...effector cells in the tumour ...CD8 T cell ...tumour cells, thereby leading to ...
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Identification of a transient lymphoid population in the murine epidermis
... canonical γδ TCR composed of Vγ3/Jγ1-Cγ1 and Vδ1/Dδ2/Jδ2-Cδ chains, and have not been found elsewhere in the adult ...first T cells to develop in the embryonic thymus, and remain the predominant CD3 ...
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Primary and Chronic HIV Infection Differently Modulates Mucosal Vδ1 and Vδ2 T-Cells Differentiation Profile and Effector Functions.
... of γδ T-cells to respond to stress-antigens or phosphoantigens [7] highlights their possible key role in fighting invading pathogens through broad antiviral mechanisms ...mucosal γδ ...
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Microbial Translocation and B Cell Dysfunction in Human Immunodeficiency Virus Disease
... and T cell Independent (TI) antigens. On the other hand, naïve B cells are also reported to proliferate and produce IgM (not IgG) in response to CpG ODN (TLR9 ligand) alone from our previous study and ...
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HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT).
... a T-cell-tropic, latently infectious virus that causes a T-cell malignancy, ATL, and inflammatory ...infiltrating T cells and T cells during viral infection, which suppresses the ...
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Filter-Dense Multicolor Microscopy.
... Immunofluorescence microscopy—microscopic detection of proteins using fluorochrome-la- beled antibodies—is a powerful approach to analyze the spatial localization of proteins in tis- sues. The technique can be used for ...
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Predictive computational modeling of the mucosal immune responses during Helicobacter pylori infection.
... CD4+ T cells have a pivotal role and crosstalk with different subsets of DC, our findings are in line with other studies suggesting that DC subsets affect Th17 differentiation and plasticity in humans, ...
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Regulatory T and B cells in asthmatic women
... Métodos: Se incluyeron cuatro grupos de mujeres para este estudio: mujeres embarazadas en su tercer trimestre, asmáticas (n = 24) y sanas (n = 43), y mujeres no embarazadas, asmáticas (n = 33) y sanas (n = 35). Las ...
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High efficiency of antiviral CD4(+) killer T cells.
... Target cells were distinguished from recipient cells by flow cytometric analysis based on CFSE fluorescence, in some cases also congenic markers, and further stratified according to MHC-II expression ...
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HIV-1 infection on Follicular Helper T cells
... The innate immune system is the first line of host defense comprising multiple mechanisms and cells (macrophages, DCs and natural killer cells (NKs)) that provide immediate protection against infection. It ...
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A convenient model of severe, high incidence autoimmune gastritis caused by polyclonal effector T cells and without perturbation of regulatory T cells.
... Treg cells was detected in the paragastric lymph node of gastritic mice, and a significantly higher percentage of Treg cells was found in the stomach of gastritic mice compared to normal mice, Treg ...
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