HIV-1
Transplanting supersites of HIV-1 vulnerability.
... three HIV-1 supersites of vulnerability to neutral- izing ...of HIV-1 Env most commonly recognized by broadly neutralizing antibodies elicited in the first 2–3 years of ...25 ...
19
Cross-reactivity of anti-HIV-1 T cell immune responses among the major HIV-1 clades in HIV-1-positive individuals from 4 continents
... documented HIV- 1 infection ⭓5 years from the time of ...of HIV-1 isolates are clade C [12, 13], only a subset of South African and Ma- lawian specimens were assayed to confirm the predominant ...
8
HIV-1-Specific CTL Recognizing a Scarce Epitope Are Not Suppressed by HIV-1 Protease Inhibitors
... suppress HIV-1 replication (in the presence or absence of PIs) was tested, using a CTL targeting an HIV-1 epitope that is presented on infected cells at limiting concentrations for CTL ...
3
Dendritic cells exposed to MVA-based HIV-1 vaccine induce highly functional HIV-1-specific CD8(+) T cell responses in HIV-1-infected individuals.
... from HIV patients express Gag intracellular protein, consistently with our previous works with MDDC from healthy subjects [44], and with other recent studies using other MVA vectors carrying HIV-1 ...
17
Variability of HIV-1 Genomes among Children and Adolescents from São Paulo, Brazil
... were sub-subtype F1, and 5 (20%) were BF1 recombinant viruses (Table 2). All chimeric viruses were unique according to their recombination profile, i.e., not assigned to any subtype or CRF (Figure 1). The ...
15
CRF19 cpx is an evolutionary fit HIV 1 variant exclusively associated with rapid progression to AIDS in Cuba
... classify HIV-1 variants into two catego- ries, namely CCR5 and CXCR4-using viruses (Lengauer et ...of HIV- 1 tropism testing state that an FPR of geno2pheno[co-receptor] ≥20% can be considered ...
11
Vertical Human Immunodeficiency Virus Type 1 - HIV-1 - Transmission A Review
... mother’s HIV-1 ...of HIV populations in the infant at birth, higher than that found in the mother, indicates that either only a few variants are originally transmitted or are initially replicating in ...
14
The integrated HIV-1 provirus in patient sperm chromosome and its transfer into the early embryo by fertilization.
... of HIV/AIDS ...integrated HIV-1 provirus was detected on the chromosomes of spermatozoa from HIV/AIDS patients but not on chromosomes from ...integrated HIV DNA can be detected in ...
6
Evolutionary and structural features of the C2, V3 and C3 envelope regions underlying the differences in HIV-1 and HIV-2 biology and infection.
... from HIV-1 and ...In HIV-2, these regions also have immune modulatory ...in HIV-1 than in ...the HIV-2 envelope and is under strong diversifying selection suggesting that, like ...
12
Compreendendo a sexualidade de indivíduos portadores de HIV-1.
... Esta investigação teve como objetivo identificar dificuldades sexuais vivenciadas por pessoas em crise de HIV-1. Trata- se de uma pesquisa de caráter descritivo, norteada pela Teoria da Crise. ...
6
A diversidade do HIV-1: uma ferramenta para o estudo da pandemia.
... do HIV-2 foi a primeira a ser elucidada, com o isolamento do SIV sm de primatas da espécie Cercocebus atys 14 ...ao HIV-1, por algum tempo o SIV agm , iso- lado de macacos verdes da África ...
12
Role of HIV-1 Infection in Addictive Behavior: A Study of a HIV-1 Transgenic Rat Model
... system. HIV-1 infection appears to affect these neural structures too. HIV-1 does not infect neurons directly, but by targeting macrophages, microglia and to a lesser extent, astrocytes ...
9
An overview of the molecular and epidemiological features of HIV-1 infection in two major cities of Bahia state, Brazil
... Clinical, epidemiological, and molecular data gener- ated in previous studies from our group in Salvador and Feira de Santana were collected and organised in a da- tabase. Thirty-two patient samples were obtained in the ...
8
SOCIO-DEMOGRAPHIC AND EPIDEMIOLOGICAL CHARACTERISTICS ASSOCIATED WITH HUMAN IMMUNODEFICIENCY VIRUS TYPE I (HIV-1) INFECTION IN HIV-1-EXPOSED BUT UNINFECTED INDIVIDUALS, AND IN HIV-1-INFECTED PATIENTS FROM A SOUTHERN BRAZILIAN POPULATION
... assay (ELISA, Murex™ HIV-1.2.0, Murex Biotech Limited, Dartford Kent England, UK), and the microparticle enzyme-immunoassay (MEIA, Abbott Axsym™ System, HIV-1/2 gO, Abbott GmbH, Weisbaden, ...
8
HIV-1 Nef enhances dendritic cell-mediated viral transmission to CD4+ T cells and promotes T-cell activation.
... We thank the members of the Wu laboratory for helpful discussions and Constance Kwas for excellent technical assistance. We thank Eric Freed for pNLAD8 construct, Olivier Schwartz for pNLAD8DNef construct, Vineet ...
10
Anti-HIV-1 activity of flavonoid myricetin on HIV-1 infection in a dual-chamber in vitro model.
... of HIV-1 life cycle, including entry, integration and maturation phases [49, ...the HIV entry by affecting the receptor CD4 and co-receptors CXCR4 and CCR5 [51], therefore blocking the communication ...
18
Imaturidade imunológica fetal e neonatal: implicações na evolução clínica da infecção pelo HIV-1 em crianças.
... pelo HIV-1 causa alterações múltiplas, contínuas e severas nas defesas do ...o HIV-1 interfere na resposta imunitária e no desenvolvimento da função imune normal, durante os períodos fetal e ...
6
Effect of maraviroc intensification on HIV-1-specific T cell immunity in recently HIV-1-infected individuals.
... recently HIV-1 infected patients with standard triple therapy could accelerate the decay of the HIV-1 reservoir ...CCR5-tropic HIV-1 (subtype B) were recruited and randomized ...
11
EPIDEMIOLOGIA MOLECULAR DO VÍRUS DA IMUNODEFICIÊNCIA HUMANA DO TIPO 1 (HIV-1) NO MUNICÍPIO DE MACAPÁ (AMAPÁ), BRASIL
... O HIV-1 exibe um extraordinário grau de variabilidade genética e foi classificado, baseado nas relações filogenéticas, em grupos, subtipos, subsubtipos e formas recombinantes circulantes ...do ...
71
The Flavonoid, Quercetin, Inhibits HIV-1 Infection in Normal Peripheral Blood Mononuclear Cells
... anti- HIV activity by differential modulation of pro-and anti- inflammatory cytokine expression in normal ...of HIV-1 replication and virus infectivity by quercetin in normal PBMC as evaluated by ...
7