IL-10 KO mice
Cytokines in innate and acquired immunity to Trypanosoma cruzi infection
... these mice is consistent with a more effective control of parasitism than that observed in WT ...that IL-10 does indeed control ...by IL-10 KO mice was reversed by ...
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A função da IL-10 na paracoccidioidomise pulmonar murina
... by IL-10 an anti- inflammatory ...that IL-10 acts as a suppressor of cellular immunity leading to deleterious effects to the ...of IL-10 in the immunity to paracoccidioidomycosis ...
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Interleukin-21 receptor signalling is important for innate immune protection against HSV-2 infections.
... heterodimer IL-21R is highly expressed by cells from the innate immune system [12,14,17–19] and IL-21 is known to increase IFN-c production and cytotoxicity of NK cells [19], which are important effector ...
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Interleukin-10 inhibits lipopolysaccharide induced miR-155 precursor stability and maturation.
... +/2 IL-10 (Figure 1A–B) suggested that the regulation of pri-miR-155 and mature miR-155 ...and IL-10 on the transcription of pri-miR-155 by using a luciferase reporter construct controlled by ...
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IL-23 p19 knockout mice exhibit minimal defects in responses to primary and secondary infection with Francisella tularensis LVS.
... [25]. IL-23p19 KO mice are unable to mount a full DTH ...in IL-23p19 KO mice are due at least in part to a defect in memory T cell ...WT mice and p19G KO ...
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Interleukin-1 receptor antagonist modulates the early phase of liver regeneration after partial hepatectomy in mice.
... in IL- 1ra KO mice. Indeed, IL-1b has been previously shown to antagonize hepatocyte proliferation ...while IL-6 is known to stimulate the priming phase of liver regeneration, previous ...
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Influência dos polimorfismos genéticos da IL-4, IL-6, IL-10 e TGF-β no carcinoma gástrico
... da IL-4 apresentam associação com a susceptibilidade para o desenvolvimento de carcinoma gástrico do tipo ...de IL-4, correlacionam-se com prevalência da gastrite ...da IL-4 parece ter um efeito ...
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Benznidazole affects expression of Th1, Th17 and Treg cytokines during acute experimental Trypanosoma cruzi infection
... and heart compared to infected animals that received no treatment. These results are in agreement with other ex- perimental studies [41, 42]. It was observed that the number of parasites was considerably lower in JLP- ...
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Alan Sher, Thomas A Wynn
... in mice but not with altered regula- tion of granuloma size (Henderson et ...these mice were unresponsive to schistosome egg antigens (Bosshardt et ...in mice with pipestem fibrosis, more eggs were ...
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Braz. Dent. J. vol.29 número1
... both KO mice were different from the ...both KO mice was higher than WT, by which we can hypothesize that TLR2 and MyD88 present a protective role in AP because in their absence MMP9 ...
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Cell-mediated immune response to Leishmania chagasi experimental infection of BALB/c immunosuppressed mice
... of mice infected with visceral Leishmania failed to produce IFN-γ and IL-2 in the first weeks of ...production, IL-4 was absent both in non-stimulated and stimulated spleen cell ...(32), IL-4 ...
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Persistent release of IL-1s from skin is associated with systemic cardio-vascular disease, emaciation and systemic amyloidosis: the potential of anti-IL-1 therapy for systemic inflammatory diseases.
... KCASP1Tg mice compared to the other two groups (n = 6, each ...KCASP1Tg mice showed decreased plasma HDL cholesterol and leptin levels, as well as increased triglyceride ...KIL-18Tg(+) mice showed ...
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Prader-Willi Critical Region, a Non-Translated, Imprinted Central Regulator of Bone Mass: Possible Role in Skeletal Abnormalities in Prader-Willi Syndrome.
... of mice deficient in the PWCR revealed a skeletal phenotype that shows strong parallels with that found in humans with ...when mice reached an older age, consis- tent with non-closure of growth-plates in ...
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A safe vaccine (DV-STM-07) against Salmonella infection prevents abortion and confers protective immunity to the pregnant and new born mice.
... Many infectious diseases which affect pregnant women can be prevented through vaccination. But vaccination in pregnant individual with live attenuated vaccine strains is always fraught with the theoretical possibility of ...
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Acute Kidney Injury Reduces Phagocytic and Microbicidal Capacities of Alveolar Macrophages
... In mice and rats, after ischaemic AKI, lung injury characterised by neutrophil infiltration, pulmonary oedema and increased chemokine and cytokine expression can be observed [13- ...
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IL-10 na patogênese da infecção por Leishmania infantum
... de IL-10 resulta em susceptibilidade à infecção por ...de IL-10 (160- ...de IL- 10 no soro de pacientes LV com uma importante diminuição da IL-10 ao final do ...
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Decreased Interleukin-10 Responses in Children with Severe Mycoplasma pneumoniae Pneumonia.
... between IL- 8, IL-10, and IL-18, and the clinical ...both IL-8 and IL-18 levels were positively correlated with CRP ...of IL-10 levels and clinical factors was not ...
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AVALIAÇÃO DE CITOCINAS PLASMÁTICAS ASSOCIADAS AO SOBREPESO E OBESIDADE EM MULHERES ADULTAS E IDOSAS
... secretam IL-1 que é induzida por estímulos inflamatórios como, por exemplo, o TNF- ...da IL-1 sistêmica refletem na regulação da taxa metabólica basal, nos níveis de glicose, pressão arterial, metabolismo ...
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Amyloid precursor protein is required for normal function of the rod and cone pathways in the mouse retina.
... APP-KO mice had functional deficits that may affect their visual ...the mice to track gratings of various widths was quantified by the optokinetic reflex and measured as the spatial frequency ...
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RESPOSTA IMUNOLÓGICA DO TIPO TH17 E SUA REPERCUSSÃO CLÍNICA NO LÚPUS ERITEMATOSO SISTÊMICO
... citocinas(IL-2, IL-4, IL-6, TGF-P, IL-10, IL-17, IFN-y e TNF-a ) em pacientes diagnosticados com lúpus eritematoso sistêmico com comprometimento renal ou com acometimento ...
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