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In vitro studies

Extended latanoprost release from commercial contact lenses: in vitro studies using corneal models.

Extended latanoprost release from commercial contact lenses: in vitro studies using corneal models.

... previous in vitro studies on prostaglandin analogues, our results can only be compared to the release of drugs from the contact lens materials with similar size and hydropho- ...Previous in ...

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Loxosceles gaucho venom-induced acute kidney injury--in vivo and in vitro studies.

Loxosceles gaucho venom-induced acute kidney injury--in vivo and in vitro studies.

... age. In Brazil, 49% of AKI, ...treated in Butantan Institute, Brazil, 4% developed VCL and none presented AKI ...[15]. In Chile, plasma creatinine was assessed in 26 of 34 VCL cases and was ...

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Flow of Red Blood Cells in Microchannel Networks: in vitro studies

Flow of Red Blood Cells in Microchannel Networks: in vitro studies

... dynamics, in vitro [5-8] and in vivo experiments ...role in several recent developments of lab-on- chip devices for blood sampling, analysis and cell culturing, aimed in a near future, ...

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Experimental chemotherapy for Chagas disease: 15 years of research contributions from in vivo and in vitro studies

Experimental chemotherapy for Chagas disease: 15 years of research contributions from in vivo and in vitro studies

... 2000). In collaboration with ...origin in the region from which the samples were collected, the 10 extracts were separated into three groups: A (Bac- charis dracunculifolia + Araucaria spp), B ...3 ...

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Non-clinical studies required for new drug development – Part I: early in silico and in vitro studies, new target discovery and validation, proof of principles and robustness of animal studies

Non-clinical studies required for new drug development – Part I: early in silico and in vitro studies, new target discovery and validation, proof of principles and robustness of animal studies

... Identification and validation of therapeutic targets The targets on target-based drug discovery are iden- tified using several molecular tools and strategies that include the evaluation of DNA/RNA (genomic) and pro- teins ...

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Braz. J. Pharm. Sci.  vol.49 número2

Braz. J. Pharm. Sci. vol.49 número2

... In vitro release studies in the presence of rat caecal content indicated the suitability of the polysaccharide locust bean gum based compression coated tablets for colonic delivery of ...

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Antifungal activity of citrus essential oil components in vitro and in vivo against penicillium digitatum pers. (sacc.)

Antifungal activity of citrus essential oil components in vitro and in vivo against penicillium digitatum pers. (sacc.)

... In vitro studies were conducted on 37 compounds present in citrus essential oil, to test their activity against Penicillium digitatum by three methods: agar diffusion, amended growth medium ...

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IP-10 is a potential biomarker of cystic fibrosis acute pulmonary exacerbations.

IP-10 is a potential biomarker of cystic fibrosis acute pulmonary exacerbations.

... The in vitro studies in airway epithelial culture and the broad literature regarding the role of IP-10 in acute and chronic infection lend biological plausibility to the findings of our ...

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Dental Press J. Orthod.  vol.17 número6

Dental Press J. Orthod. vol.17 número6

... Many in vitro studies have already analyzed the mechanical properties of conventional GICs and res- in-modified GICs used for orthodontic purposes, how- ever, few studies have ...

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J. Braz. Chem. Soc.  vol.26 número4

J. Braz. Chem. Soc. vol.26 número4

... Evaluation of degradation products is essential for future biological and toxicological investigations, aiming at maintenance of safety and efficacy of pharmaceutical products. In this study, DAB stability study ...

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Estudo genotóxico e carcinogênico da exposição ao pó de cromo trivalente em Rattus norvegicus

Estudo genotóxico e carcinogênico da exposição ao pó de cromo trivalente em Rattus norvegicus

... PFEIFER, 2002; HIRAKU et al., 2014). Estudos apontam que alguns metais carcinogênicos, como o Cr, Cd, Pb, Co e Fe, também induzem a produção de EROs relacionada com a inflamação e a subsequente lesão oxidativa do DNA em ...

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Effect Of 2% Chlorhexidine Application on the Bonding Effectiveness of Different Dentin Adhesives in Normal and Caries Affected Dentin in Primary  Teeth: an in Vitro Study

Effect Of 2% Chlorhexidine Application on the Bonding Effectiveness of Different Dentin Adhesives in Normal and Caries Affected Dentin in Primary Teeth: an in Vitro Study

... sectioned in two halves and after preparing a flat surface of superficial dentin, were randomly divided into 12 groups; according to dentin condition (normal and caries affected), type of adhesive (Clearfil SE ...

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IN VITRO AND IN VIVO EVALUATION OF PIROXICAM LOADED CERAMIC NANOPARTICLES

IN VITRO AND IN VIVO EVALUATION OF PIROXICAM LOADED CERAMIC NANOPARTICLES

... drug in the ...for in vivo efficacy studies according to the instructions set by ...accommodated in a set of controlled conditions. The animals were placed separately in PP cages having ...

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Rev. Soc. Bras. Med. Trop.  vol.46 número3

Rev. Soc. Bras. Med. Trop. vol.46 número3

... infection in the anogenital tract has been associated with the involvement of cells with regulatory ...CD25 in cervical stroma cells with and without pathological changes or HPV infection to better ...

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Rev. bras. farmacogn.  vol.24 número3

Rev. bras. farmacogn. vol.24 número3

... present in a 420 mg capsule (Angenot, ...consumer in the long run, and especially during ...effects in vivo only led to the rejection of this food supplement by the Belgian Ministry of Health ...

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Cellular immune responses to nine Mycobacterium tuberculosis vaccine candidates following intranasal vaccination.

Cellular immune responses to nine Mycobacterium tuberculosis vaccine candidates following intranasal vaccination.

... cells in lung and spleen after in vitro stimulation with individual ...vaccination in Dimethyl-dioctadecyl-ammonium bromide (DDA)-monopho- sphoryl lipid A (MPL) adjuvants, all nine vaccine ...

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The dual PI3K/mTOR inhibitor NVP-BEZ235 induces tumor regression in a genetically engineered mouse model of PIK3CA wild-type colorectal cancer.

The dual PI3K/mTOR inhibitor NVP-BEZ235 induces tumor regression in a genetically engineered mouse model of PIK3CA wild-type colorectal cancer.

... Some studies have suggested that PIK3CA mutant cancers are ‘‘oncogenically addicted’’ to PI3K signaling, leading to increased sensitivity to PI3K inhibitor therapy ...seen in only 17% of human CRC, this ...

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Bauhinia forficata Link Shoot Regeneration: Histological Analysis of Organogenesis Pathway

Bauhinia forficata Link Shoot Regeneration: Histological Analysis of Organogenesis Pathway

... Shoot buds formed were isolated and transferred to a same composition culture medium without plant growth regulator for elongation. It has been observed for various legumes that high concentration of cytokinin stimulated ...

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Clinics  vol.68 número2

Clinics vol.68 número2

... Statistical evaluation was performed using Graph Pad software (Prism 3.0) and the univariate program in SPSS 11.5 software. Data are expressed as the mean¡SD. Differences between groups were analyzed by one-way ...

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Sphingosine 1-phosphate promotes activation of caprine preantral follicle in vitro

Sphingosine 1-phosphate promotes activation of caprine preantral follicle in vitro

... culture in each medium. Each follicle was examined in every section in which it appeared and matched with the same follicle in adjacent sections to avoid double counting, thus ensuring that ...

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