Liver injury
Free radical scavenging activity of Berberine in acetaminophen induced liver injury
... induced liver toxicity was first reported in the United States in the mid-1980s, since then a rising trend has been reported from the ...AAP-induced liver injury is mediated through production of ...
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Exogenous normal lymph reduces liver injury induced by lipopolysaccharides in rats
... The liver is one of the target organs damaged by septic shock, wherein the spread of endotoxins ...(LPS)-induced liver injury in ...Hepatocellular injury indices and hepatic histomorphology, ...
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Edaravone protects endotoxin-induced liver injury by inhibiting apoptosis and reducing proinflammatory cytokines
... the liver injury induced by D-galactosamine (GalN) and lipopolysaccharide (LPS) in female BALB/c ...and liver injury was biochemically and histologically ...the liver were assayed by ...
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Association between age at diagnosis and degree of liver injury in hepatitis C
... Another remarkable finding of this study was the impact of age at diagnosis on the degree of liver injury, with a growing prevalence of advanced fibrosis and a progressive reduction in the number of mild ...
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Glycyrrhizin attenuates endotoxin- induced acute liver injury after partial hepatectomy in rats
... induces liver dysfunc- tion, or even multiple organ failure and ...acute liver injury after partial hepatecto- ...the liver against endotoxin-induced injury, especially after massive ...
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Polymorphisms in CTLA4 influence incidence of drug-induced liver injury after renal transplantation in Chinese recipients.
... This study included 864 transplantation recipients (764 cadaver donor cases and 100 living donor cases; 536 men and 328 women) in the Shanghai Organ Transplantation Center between Jan 2000 and Oct 2011. Ninety patients ...
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Hepatoprotective effect of Alhagi sparsifolia against Alcoholic Liver injury in mice
... and liver disorders (Shaker, Mahmoud, Mnaa, 2010; Aidouri, Alessa, 2010) Alhagi sparsifolia is rich in biologically active phytochemicals such as polysaccharides, phenolics, flavonoids and alkaloids along with ...
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Role of IRAK-M in alcohol induced liver injury.
... alcohol-induced liver injury and most studies have focused on positive regulation of innate ...alcoholic liver injury. We established an alcohol-induced liver injury model using ...
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Hyper-activated pro-inflammatory CD16 monocytes correlate with the severity of liver injury and fibrosis in patients with chronic hepatitis B.
... cholestatic liver damage [29,30] and further indicated that the accumulated neutrophils in liver, as well as the decreased numbers of neutrophils in peripheral blood, are associated with liver ...
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SB203580 Modulates p38 MAPK Signaling and Dengue Virus-Induced Liver Injury by Reducing MAPKAPK2, HSP27, and ATF2 Phosphorylation.
... We examined the same path, whether SB203580 reduces the phosphorylation of its down- stream kinases including MAPKAPK2 and ATF-2 in DENV infection. We found that SB203580 treatment reduces the phosphorylation of both ...
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Exercises in hot and humid environment caused liver injury in a rat model.
... analyzed liver cells of all three groups with JC-1 dye and flow cytometry for apoptosis rates in addition to liver tissue 8 - hydroxy deoxyguanosine (8 - OhdG) and blood serum IL–6, tumor necrosis factor ...
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The outcome of acute schistosomiasis infection in adult mice with postnatal exposure to maternal malnutrition
... These findings indicate that the host-parasite relation- ship was more balanced. In conclusion, these observations suggest that protein or energy restriction during lactation has a prominent effect on the course of acute ...
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Braz. J. Pharm. Sci. vol.53 número1
... the main organ in body, which metabolizes chemicals and drug. It has been well known that enzyme AST and ALT are markers of hepatocyte damage and the high level of AST and ALT is an important marker for liver ...
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Renal Impairment with Sublethal Tubular Cell Injury in a Chronic Liver Disease Mouse Model.
... (DDC)–induced liver injury is a well-established mouse model to study formation of Mallory bodies in various liver diseases and the mecha- nisms of oval cell activation and proliferation ...
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Effect of N-acetylcysteine in liver ischemia-reperfusion injury after 30% hepatectomy in mice
... thiol, in which nitric oxide reacts with glutathione, improving the microcirculation, attenuating vascular congestion and tissue injury. Also ALT level was lower after NAC use. AST and ALT are useful screening ...
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Mesenchymal stem cells promote liver regeneration and prolong survival in small-for-size liver grafts: involvement of C-Jun N-terminal kinase, cyclin D1, and NF-κB.
... recipient liver that were able to differentiate into albumin+ cells in liver injury models or reduced size liver transplantation [25, 38, ...injured liver did not occur for at least 7 ...
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Hepatoprotective Effects of Iranian Hypericum scabrum Essential Oils Against Oxidative Stress Induced by Acetaminophen in Rats
... world (Robson 1990; Yazaki and Okada 1994). In Iran, 19 species of five sections exist (Azadi 1999), which are generally known locally with the names “Hofarighon, Alafe chai and Gole raei” (Zargari 1985). Studies have ...
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The absence of obstructive sleep apnea may protect against non-alcoholic fatty liver in patients undergoing bariatric surgery.
... Our study confirmed several known factors associated with normal liver histology including black race, low HOMA-IR, and low ALT. Uniquely, we found that the absence of sleep apnea was significantly protective ...
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Braz. J. Cardiovasc. Surg. vol.31 número4
... Halogenated inhalational anesthetics are associated with liver injury. Halothane, enflurane, isoflurane, and desflurane are metabolized through the metabolic pathway involving cytochrome P-450 2E1 (CYP2E1) ...
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The Impact of Liver Cell Injury on Health-Related Quality of Life in Patients with Chronic Liver Disease.
... Chronic liver diseases (CLD) are a major cause of morbidity and mortality ...chronic liver disease often suffer from unspecific symptoms including fatigue, muscle and joint pain, loss of appetite, digestive ...
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