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mode of binding

An Unexpected Mode Of Binding Defines BMS948 as A Full Retinoic Acid Receptor β (RARβ, NR1B2) Selective Agonist.

An Unexpected Mode Of Binding Defines BMS948 as A Full Retinoic Acid Receptor β (RARβ, NR1B2) Selective Agonist.

... understanding of how ligand binding leads to receptor regulation has been greatly ad- vanced by structural studies of RAR LBDs in complex with different pharmacological classes of retinoids as ...

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The structure of an LIM-only protein 4 (LMO4) and Deformed epidermal autoregulatory factor-1 (DEAF1) complex reveals a common mode of binding to LMO4.

The structure of an LIM-only protein 4 (LMO4) and Deformed epidermal autoregulatory factor-1 (DEAF1) complex reveals a common mode of binding to LMO4.

... alignment of characterised LIM-peptide ...for binding based on mutational studies, boxed residues have been shown to be buried in the hydrophobic core between the two zinc-binding modules in the ...

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A time-dependent, two-step binding mode of the nitro dye flavianic acid to trypsin in acid media

A time-dependent, two-step binding mode of the nitro dye flavianic acid to trypsin in acid media

... treatment of Scatchard, Hill and Tandford analyses showed the binding of flavianate to trypsin to be a ligand-in- duced protein transconformation ...new binding sites are created on the ...

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Estudos in silico da interação da enzima InhA de Mycobacterium tuberculosis com pequenas moléculas do tipo fármaco

Estudos in silico da interação da enzima InhA de Mycobacterium tuberculosis com pequenas moléculas do tipo fármaco

... conversion of regular SS (α-helix mainly) in to irregular structures (coils) in the InhA-PIF ...substrate binding loop [7], comprehending helices 6 and 7, and that the overall Rossmann fold [56-58] ...

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In silico analysis of binding interaction of conantokins with NMDA receptors for potential therapeutic use in Alzheimer ’s disease

In silico analysis of binding interaction of conantokins with NMDA receptors for potential therapeutic use in Alzheimer ’s disease

... insight of the three-dimensional structure formed be- tween two biomolecules and to correlate this informa- tion to find a potential drug candidate for these receptors ...the binding mode of ...

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Conservation of carbohydrate binding interfaces: evidence of human HBGA selection in norovirus evolution.

Conservation of carbohydrate binding interfaces: evidence of human HBGA selection in norovirus evolution.

... relatedness of human noroviruses in terms of their interaction with the HBGA ...HBGA binding patterns within genogroups share common receptor binding interfaces in their interactions with ...

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MARs Wars: heterogeneity and clustering of DNA-binding domains in the nuclear matrix

MARs Wars: heterogeneity and clustering of DNA-binding domains in the nuclear matrix

... increases binding of heterologous S/MARs to the nuclear matrix in ...assay of the human MAR from the beta-interferon gene domain ...% of the input DNA; 2 – incubation of the labelled ...

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Munc13-like skMLCK variants cannot mimic the unique calmodulin binding mode of Munc13 as evidenced by chemical cross-linking and mass spectrometry.

Munc13-like skMLCK variants cannot mimic the unique calmodulin binding mode of Munc13 as evidenced by chemical cross-linking and mass spectrometry.

... neuronal binding partners of calmodulin (CaM) are Munc13 proteins as essential presynaptic regulators that play a key role in synaptic vesicle priming and are crucial for presynaptic short-term ...

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Simultaneous mode A and mode B echobiometry of senile cataractous eyes in dogs

Simultaneous mode A and mode B echobiometry of senile cataractous eyes in dogs

... Fifteen male and female dogs, aging from eight to 14-year-old, affected with different stages of senile cataracts were used. The dogs were clinically and ophthalmologic evaluated using pupillary light reflex, ...

5

Chronic kidney patients in hemodialysis: a study on the mode of psychosocial theory of Roy

Chronic kidney patients in hemodialysis: a study on the mode of psychosocial theory of Roy

... type of confrontation of each ...identification of the physical and psychosocial needs of this clientele, through clinical reasoning based on a theory of ...care of chronic ...

9

Distinct molecular strategies for Hox-mediated limb suppression in Drosophila: from cooperativity to dispensability/antagonism in TALE partnership.

Distinct molecular strategies for Hox-mediated limb suppression in Drosophila: from cooperativity to dispensability/antagonism in TALE partnership.

... role of Hth on AbdB binding to DMX-R suggests that down regulating the levels of Hth in the posterior abdomen is essential for proper AbdB-mediated Dll ...level of Hth to a level similar to ...

15

Reduction of heat sink common-mode currents in switching mode power supply circuits

Reduction of heat sink common-mode currents in switching mode power supply circuits

... Switching Mode Power Supply circuits. The validation of the input impedances of the heat sinks have verified that the input impedances can be increased at some frequencies up to 45 dB due to the ...

5

Computational  of the substrate binding mode in  III oxidase

Computational of the substrate binding mode in III oxidase

... position of helixes H2 (Ser79-Lys87) and H8 (Arg275-Leu281), which may either move apart or towards each other, thereby opening or closing access from the solvent to a cavity which contains the putative active ...

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Profiling of aerosol microphysical properties at several EARLINET/AERONET sites during July 2012 ChArMEx/EMEP campaign

Profiling of aerosol microphysical properties at several EARLINET/AERONET sites during July 2012 ChArMEx/EMEP campaign

... D’Amico, G., Freudenthaler, V., Giles, D., Granados-Muñoz, M. J., Kokkalis, P., Nicolae, D., Oshchepkov, S., Papayannis, A., Perrone, M. R., Pietruczuk, A., Rocadenbosch, F., Sicard, M., Slutsker, I., Talianu, C., De ...

57

A modern mode of activation for nucleic acid enzymes.

A modern mode of activation for nucleic acid enzymes.

... annealing of two overlapping oligonucleotides that were then filled in by PCR using Vent DNA polymerase (New England Biolab), producing a double-stranded DNA ...Each of these fragments was provided with a ...

7

Thermodynamic Analysis of a Mixed-Mode Solar Dryer

Thermodynamic Analysis of a Mixed-Mode Solar Dryer

... quality of the dried product. This work was carried out in the department of mechanical engineering, University of Agriculture, Makurdi Nigeria, ...necessity of this research stemmed from the ...

10

Lat. Am. j. solids struct.  vol.13 número8

Lat. Am. j. solids struct. vol.13 número8

... range of mixed-mode loading with assumption of linear elastic conditions according ASTM D5045 standards, in which linear elastic fracture mechan- ics and plane strain conditions are the primary ...

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Optimal Solutioning Mode of the Assignment Problems

Optimal Solutioning Mode of the Assignment Problems

... In the present paper we are presenting an optimal way to solve the Asignment problems using the Network Modeling Module of the WinQSB software, by the Hungarian algorithm. Meantime, the given problem was solved ...

6

Mode resolved density of atmospheric aerosol particles

Mode resolved density of atmospheric aerosol particles

... Laaksonen, A., Kulmala, M., O’Dowd, C. D. , Joutsensaari, J., Vaattovaara, P., Mikkonen, S., Lehtinen, K. E. J., Sogacheva, L., Dal Maso, M., Aalto, P., Pet ¨aj ¨a, T., Sogachev, A., JunYoon, Y., Lihavainen, H., Nilsson, ...

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Lat. Am. j. solids struct.  vol.8 número3

Lat. Am. j. solids struct. vol.8 número3

... First order shear deformation theories (FSDTs) can be considered as improvements over classical plate theory. It is based on the assumption that straight lines normal to undeformed midplane remain straight but not ...

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