Myeloid leukemia
Indeterminate Cell Histiocytosis in Association with Acute Myeloid Leukemia
... Copyright © 2010 Filipa Ventura et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
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Bone marrow transplantation and acute myeloid leukemia: Brazilian guidelines
... et al. NPM1 but not FLT3-ITD mutations predict early blast cell clearance and CR rate in patients with normal karyotype. AML(NK-AML) or high-risk myelodysplastic syndrome (MDS). Blood. 2009;113(21):5250-3. 20. Gaidzik ...
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BCR-ABL promotes PTEN downregulation in chronic myeloid leukemia.
... Figure 1. BCR-ABL downregulates PTEN expression. A) Left panel: evaluation of PTEN levels of expression in BCR-ABL-pcDNA3.1 transfected NIH3T3. Right panel: quantification of PTEN levels. B) PTEN mRNA levels in BCR-ABL ...
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Isolated trisomy 11 in de novo acute myeloid leukemia
... 16. Byrd JC, Mrózek K, Dodge RK, Carrol AJ, Edwards CG, Arthur DC et al. Pretreatment cytogenetic abnormalities are predictive of induction of relapse, and overall survival en adult patients with de novo acute ...
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Atypical chromosome abnormalities in acute myeloid leukemia type M4
... phocytes and 46% blast cells). A bone marrow aspirate showed hypercelullarity with 78% of myeloblasts and monocyte lineage cells. Cytochemical tests showed 44% Sudan-Black positive and 10% periodic acid Schiff (PAS) ...
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Outcomes of allogeneic stem cell transplantation among patients with acute myeloid leukemia presenting active disease: Experience of a single European Comprehensive Cancer Center
... The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. Blood. 1998; 92(7):2322-33. 5. Slovak ML, Kopecky KJ, Cassileth PA, Harrington DH, Theil KS, ...
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Mesenchymal Stem Cells (MSC) Regulate Activation of Granulocyte-Like Myeloid Derived Suppressor Cells (G-MDSC) in Chronic Myeloid Leukemia Patients.
... Chronic myeloid leukemia (CML) is a hematopoietic stem cell malignancy characterized by the t(9;22) chromosomal translocation that generates the BCR/ABL oncogene ...eliminate leukemia stem cells ...
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ANALYSIS OF mRNA TRANSCRIPTS IN CHRONIC MYELOID LEUKEMIA PATIENTS
... Chronic myeloid leukemia (CML) is a clonal dis- ease characterized by the presence of the hybrid gene BCR/ ABL, usually located on the Philadelphia chromosome which results from reciprocal translocation ...
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Identification of circulating microRNAs as potential biomarkers for detecting acute myeloid leukemia.
... Acute myeloid leukemia (AML) is the most common acute leukemia in adults. The disease is characterized by various cytogenetic and molecular abnormalities with distinct prognoses and gene expression ...
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Acute myeloid leukemia in elderly patients: experience of a single center
... Acute myeloid leukemia (AML) is a disease predominantly of older adults. Treatment of AML in the elderly is complicated not only by comorbidities but also by the high prevalence of poor prognosis markers. ...
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Granulomatous rosacea: Like leukemid in a patient with acute myeloid leukemia
... Introduction. Skin findings in leukemias may be divided into specific lesions (leukemia cutis) and non-specific lesions (leu- kemids) which may be found in up to 80% of all patients with leukemias. The leukemids ...
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Molecular-cytogenetic variant in chronic myeloid leukemia
... Chronic myeloid leukemia (CML) was the first neoplastic disease to be linked to a genetic abnormality and is the best studied molecular model of leukemia. The increased and cumulative knowledge of ...
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Association between MTHFR polymorphisms and acute myeloid leukemia risk: a meta-analysis.
... of leukemia occur every year [1] and acute myeloid leukemia (AML) is the most common acute leukemia ...of leukemia is still unknown. Leukemia is likely to be associated with ...
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Gold nanoparticles for nanotheranostics in leukemia – Addressing Chronic Myeloid Leukemia
... chronic myeloid leukemia using its genetic marker, BCR-ABL1 fusion transcript; iii) Total RNA extracted from white blood cells is then mixed with Au-nanoprobes and heated to promote ...
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ACUTE MYELOID LEUKEMIA - M3V WITH DEEP VEIN THROMBOSIS, A RARE PRESENTATION
... overshadowed in acute leukaemia due to increased incidence of bleeding and infections. Acute Myeloid Leukemia is a morphologically and genetically heterogenous disease. One subtype with specific morphology ...
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Nucleophosmin 1 expression in acute myeloid leukemia
... The aim of this study is to evaluate the effects of Nucleophosmin1 mutation on the clinical presentations, prognosis, diagnosis and the treatment of acute myeloid leukemia. Thirteen articles were extracted ...
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Chronic myeloid leukemia (CML): prognostic factors and survival analysis
... during the first year after diagnosis, 12 percent during the second and 22,5 percent per year during the next eight years. T he staging system proposed here perm its our population to be[r] ...
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Evaluating the equilibrium association constant between artinM lectin and myeloid leukemia cells by impedimetric and piezoelectric label free approaches
... NB4 leukemia cells were evaluated under Langmuir adsorption (or biochemistry-binding) ...NB4 leukemia cell line was chosen because of its known susceptibility to ArtinM death ...
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Global Identification of EVI1 Target Genes in Acute Myeloid Leukemia.
... human myeloid malignancy of poor prognosis and is overexpressed in 8–10% of adult AML and strikingly up to 27% of pediatric MLL-rearranged ...terminal myeloid differentiation and cell cycle regulation to be ...
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Integrative meta-analysis of differential gene expression in acute myeloid leukemia.
... We then identified genes that were reported in multiple studies. Of the total 4,918 genes, 1,686 (34.3%) were reported in more than one study. We ranked genes that were listed in at least 8 studies by number of ...
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