Neural differentiation
Assessing pseudogene expression during neural differentiation by RNA-Seq
... Pseudogene expression is tissue-specific, with testis and brain showing the highest levels of their transcription (Soumillon et al., 2013). Recent findings suggest that pseudogenes may play functional role on ...
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Neural Differentiation of Mouse Bone Marrow-Derived Mesenchymal Stem Cells Treated with Sex Steroid Hormones and Basic Fibroblast Growth Factor
... Some researchers have revealed that intrave- nously injected BM-MSCs migrate to the stroke injury site, differentiate into cells expressing neuronal markers and restore the damaged neu- ral cells in rodents. Recent ...
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FGF signalling regulates chromatin organisation during neural differentiation via mechanisms that can be uncoupled from transcription.
... many differentiation genes fail to be transcribed, restores chromatin decompaction and a more central nuclear position of the Pax6 locus suggests that RA acts first to inhibit FGFR signalling and that FGF is ...
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Neural differentiation of embryonic stem cells in vitro: a road map to neurogenesis in the embryo.
... vitro neural differentiation starting from embryonic stem (ES) cells, aimed at generating regionally specified neural progenitors and/or differ- entiated neuronal and glial ...of neural ...
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Membrane-enriched proteome changes and prion protein expression during neural differentiation and in neuroblastoma cells
... prefractionation step used to select the membrane pro- tein subset (Fig. 5a). Enrichment in proteins involved in “focal adhesion” might be consistent with a role of PrP in the modulation of cell adhesion and stability of ...
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A new module in neural differentiation control: two microRNAs upregulated by retinoic acid, miR-9 and -103, target the differentiation inhibitor ID2.
... in neural differentiation control: miR-9 promotes neural fate determination whereas ID2 supports proliferation and self-renewal of neural precursor cells ...of neural ...
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Evaluation of silicon nitride as a substrate for culture of PC12 cells: an interfacial model for functional studies in neurons.
... for neural differentiation, and we characterized their interaction based on cell behavior when seeded on the tested ...morphological differentiation compared to those cultured on a plastic culture ...
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Use of Ferritin Expression, Regulated by Neural Cell-Specific Promoters in Human Adipose Tissue-Derived Mesenchymal Stem Cells, to Monitor Differentiation with Magnetic Resonance Imaging In Vitro.
... the neural differentiation of stem cells using ferritin transgene expression, under the control of a neural-differentia- tion-inducible promoter, and magnetic resonance imaging ...three neural ...
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Short-Term Withdrawal of Mitogens Prior to Plating Increases Neuronal Differentiation of Human Neural Precursor Cells
... hNPC were plated onto coverslips (approximately 5 neuro- spheres per coverslip) to allow migration and neural differentiation of cells. To verify whether growth factors starvation could change the ...
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Amyloid β peptide and p63 : two prime triggers of neural apoptosis and differentiation
... The p63 protein, in turn, has been extensively described as a key regulator of development and maintenance of stratified epithelial tissues, having a tissue-specific distribution, mostly detectable in the basal layer of ...
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SCRATCH2 na diferenciação neural em embriões e em células-tronco
... conserved between the homologues of SCRATCH2 in chicken, human, rat and mice. All single mutants forms reduced SCRATCH2 repressor ability. Overexpression of cSCRATCH2 single point mutants in HEK293T and chicken embryos ...
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Type-1 (CB1) cannabinoid receptor promotes neuronal differentiation and maturation of neural stem cells.
... and differentiation, such as the p38 MAPK and AKT, were either not phosphorylated during NSC differentiation (p38) or affected by ACEA only transiently (AKT at 48 hours) (Figure ...NSC ...
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Dehydroepiandroesteron Accompanied Retinoic Acid Enhances Differentiation of P19 Embryonal Stem Cells into Neural Cells
... 15. Jones-Villeneuve EM, Rudnicki MA, Harris JF, McBurney MW. Retinoic acid-induced neural differentiation of embryo- nal carcinoma cells. Mol Cell Biol. 1983; 3: 2271-2279. 16. Maden M. Retinoic acid and ...
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Neural induction from ES cells portrays default commitment but instructive maturation.
... the neural fate, we stained the cells with neural stem cell/progenitor markers such as Sox1, Sox2 and nestin both prior to and after inducing ...for neural committed population [19] was detected ...
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Effects of FGF-2 and EGF removal on the differentiation of mouse neural precursor cells
... and neural precursor cells (NPC) may become the ideal candi- dates for neural transplantation in a wide range of ...NPC differentiation and may contribute to a better understanding of mechanisms of ...
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Self-contained induction of neurons from human embryonic stem cells.
... All recombinant DNA experiments conformed to National Institute of Health (NIH) guidelines. First, a pGFP plasmid, in which hrGFP (Stratagene, La Jolla, CA) was expressed under the control of a CAG promoter (a gift from ...
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Extensive neuronal differentiation of human neural stem cell grafts in adult rat spinal cord.
... RNA samples were extracted from 10 7 NSCs at various time points of differentiation in vitro (0, 14, 29, and 42 d after withdrawal of bFGF) using Trizol (Invitrogen [http://www. invitrogen.com/]). Residual DNA was ...
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The homeobox gene Gsx2 regulates the self-renewal and differentiation of neural stem cells and the cell fate of postnatal progenitors.
... the differentiation of NSCs in culture into neurons, astrocytes and oligodendrocytes, and it promotes the maintenance of NSC-derived progenitors as cycling, undifferentiated ...
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Signi fi cance of Neural Crest in Tooth Development: The Molecular Signature
... the neural crest cells associated with r3 and r5 undergo apoptosis because of the presence of the apoptosis-inducing molecule ...rhombomeric neural crest cells and the expression of products of the Hox-b ...
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Uniaxial mechanical strain modulates the differentiation of neural crest stem cells into smooth muscle lineage on micropatterned surfaces.
... NCSC differentiation is not ...the differentiation of NCSCs into smooth muscle (SM) ...the differentiation of NCSCs into Schwann ...by neural induction medium but further enhanced by ...the ...
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