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Neuronal loss

Hippocampal adaptive response following extensive neuronal loss in an inducible transgenic mouse model.

Hippocampal adaptive response following extensive neuronal loss in an inducible transgenic mouse model.

... Neuronal loss is a common etiology of a variety of neurode- generative disorders (Alzheimer’s (AD), Parkinson’s (PD), and Huntington’s disease (HD) and brain traumas (stroke, epilepsy, and traumatic brain ...

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Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2.

Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2.

... The neuronal loss in G2019S LRRK2 mice (line 340) most likely reflects higher levels of transgene expression and detectable expression in dopaminergic neurons of the substantia nigra in this mouse ...The ...

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Loss of aPKCλ in differentiated neurons disrupts the polarity complex but does not induce obvious neuronal loss or disorientation in mouse brains.

Loss of aPKCλ in differentiated neurons disrupts the polarity complex but does not induce obvious neuronal loss or disorientation in mouse brains.

... that neuronal deletion of aPKCl induced reduction of the total fraction of aPKCs without inducing expression of aPKCf and ...apparent neuronal loss or degeneration in the brain, even in aged ...

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Temporal lobe epilepsy with mesial temporal sclerosis: hippocampal neuronal loss as a predictor of surgical outcome

Temporal lobe epilepsy with mesial temporal sclerosis: hippocampal neuronal loss as a predictor of surgical outcome

... Objective: To analyze retrospectively a series of patients with temporal lobe epilepsy (TLE) and mesial temporal sclerosis (MTS), and the association of patterns of hippocampal sclerosis with clinical data and surgical ...

6

Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.

Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.

... A DHE fluorescence signal is detected when DHE and O 2 N 2 react and the oxidized DHE is incorporated into DNA. So, DHE is widely used for imaging intracellular O 2 N 2 both in vitro and in vivo [37–39]. During MPTP ...

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Surgical and postmortem pathology studies: contribution for the investigation of temporal lobe epilepsy

Surgical and postmortem pathology studies: contribution for the investigation of temporal lobe epilepsy

... after being submitted to surgical treatment for drug-resis- tant TLE. he hippocampus resected during surgery showed a pathological pattern consistent with HS, while the con- tralateral hippocampus, studied in the ...

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Arq. NeuroPsiquiatr.  vol.56 número3A

Arq. NeuroPsiquiatr. vol.56 número3A

... cerebral neuronal loss, spongiosis and severe gliosis in the cerebral cortex, basal ganglia and ...and neuronal atrophy up to the high cervical level of the spinal cord ...and neuronal ...

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Omega3 fatty acids : possible  mechanisms in the model of global ischemia in rats

Omega3 fatty acids : possible mechanisms in the model of global ischemia in rats

... Our data showed that brain ischemia signiicantly impaired spatial memory, and this efect was completely reversed ater �3 treatments. Evidences indicate that tran- sient global ischemia may lead to severe impairments in ...

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Phenotype of transgenic mice carrying a very low copy number of the mutant human G93A superoxide dismutase-1 gene associated with amyotrophic lateral sclerosis.

Phenotype of transgenic mice carrying a very low copy number of the mutant human G93A superoxide dismutase-1 gene associated with amyotrophic lateral sclerosis.

... We have demonstrated that VLE mice carrying 4 copies of the mutant human G93A SOD1 gene on the mixed B6/SJL background have clinical motor and pathologic changes with neuronal loss and translocation of ...

6

Clinics  vol.66 suppl.1

Clinics vol.66 suppl.1

... overt neuronal loss in the entorhinal cortex, hippocampal CA1 field, or cingulate cortex through 18 months of age in PDAPP ...synaptic loss, and a rather marked hippocampal atrophy was observed as ...

10

Can molecular imaging techniques identify biomarkers for neuropsychiatric disorders?

Can molecular imaging techniques identify biomarkers for neuropsychiatric disorders?

... An example of the use of PET and SPECT to identify biomarkers of NPD are the dopamine transporter (DAT) radiotracers that evaluate dopamine neuronal loss in Parkinson’s disease (PD). The DAT are located in ...

3

Arq. NeuroPsiquiatr.  vol.61 número4

Arq. NeuroPsiquiatr. vol.61 número4

... ABSTRACT - Frontotem p oral d em entia (FTD) is the third -lead ing cause of cortical d em entia after Alzheim er’s d isease and Lew y b od y d em entia, and is characterized b y a d em entia w here b ehavioral d isturb ...

6

Pregabalin attenuates excitotoxicity in diabetes.

Pregabalin attenuates excitotoxicity in diabetes.

... Lithium-pilocarpine seizure modeling. On day 10, all rats were injected with lithium chloride (3 meq/kg; i.p.) and methylscopolamine (25 mg/kg; s.c.), before seizures were induced with pilocarpine injections (60 mg/kg; ...

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Activation and involvement of the lateral-posterior nucleus of the thalamus after a single generalized tonic-clonic seizure

Activation and involvement of the lateral-posterior nucleus of the thalamus after a single generalized tonic-clonic seizure

... and neuronal loss have been observed in ...lateral–posterior neuronal activation may be observed shortly after a single generalized seizure in rats submitted to the pilocarpine model of ...that ...

4

J. epilepsy clin. neurophysiol.  vol.12 número1 suppl.1

J. epilepsy clin. neurophysiol. vol.12 número1 suppl.1

... hipocampal neuronal loss and impairment of cognitive and neuropsychological ...dynamic neuronal plasticity phenomena in the hipocampal formation associated with ...review neuronal and glial ...

8

Lovastatin reduces neuronal cell death in hippocampal CA1 subfield after pilocarpine-induced status epilepticus: preliminary results

Lovastatin reduces neuronal cell death in hippocampal CA1 subfield after pilocarpine-induced status epilepticus: preliminary results

... hippocampal neuronal loss after pilocarpine-induced status epilepticus (SE) Method: Adult male Wistar rats were divided into four gro u p s : (A) control rats, received neither pilocarpine nor lovastatin ...

5

Influence of gear loss factor on the power loss prediction

Influence of gear loss factor on the power loss prediction

... power loss obtained with ...gear loss factor. In order to decide which gear loss factor formulation is better suited for the authors study, this factor was calculated for seven different gear ...

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Base neuronal dos potenciais evocados auditivos

Base neuronal dos potenciais evocados auditivos

... A Neuropatia Auditiva é um termo utilizado para descrever condições que são encontradas em pacientes com audição compatível com função coclear normal e alteração na sincronia neural. Esta desordem consiste no ...

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Arq. Gastroenterol.  vol.48 número3

Arq. Gastroenterol. vol.48 número3

... Images were captured by a high resolution camera (Olympus QColor 3; Olympus, Melville, NY, USA) coupled to an optical microscope (Olympus BX 41, Tokyo, Japan) at 400X magniication, digitalized on a computer using the ...

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Despopulação neuronal pancreática em chagásicos crônicos.

Despopulação neuronal pancreática em chagásicos crônicos.

... despopulação neuronal do órgão teria ocorrido há muito tempo, até mesmo na fase aguda da tr ipanossomíase, não havendo fatores locais que lhe promovessem o ...

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