Non-triple-negative breast cancer
Prevalence of Germline Mutations in Genes Engaged in DNA Damage Repair by Homologous Recombination in Patients with Triple-Negative and Hereditary Non-Triple-Negative Breast Cancers.
... consecutive breast cancer patients described previously [15] we studied a group of 165 consecutive women with TNBC unselected for family history and a group of 46 consecutive patients with ...with ...
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HET0016, a selective inhibitor of 20-HETE synthesis, decreases pro-angiogenic factors and inhibits growth of triple negative breast cancer in mice.
... Single Photon Emission Computed Tomography (SPECT) Study Succinimidyl 6-hydrazinopyridine-3-carboxylate hydrochloride was synthesized and conjugated with rat VEGF-c, a recombinant rat VEGF-c (Prospec, Rehovot, Israel), ...
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The long non-coding RNA ADAMTS9-AS2 was identified as a potential prognostic biomarker in triple-negative breast cancer / O RNA longo não codificador ADAMTS9-AS2 foi identificado como um potencial biomarcador prognóstico no câncer de mama triplo negativo
... To validate the previous findings, we downloaded clinical-pathological data of patients with breast cancer, and data containing expression values of ADAMTS9-AS2. We utilized the expression median and ...
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A prognostic model for triple-negative breast cancer patients based on node status, cathepsin-D and Ki-67 index.
... a non-histone nuclear protein that is closely linked to proliferation ...in breast carcinomas, but the correlation between Ki-67 expression and chemosensitivity in the triple- negative ...
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How many diseases is triple negative breast cancer: the protagonism of the immune microenvironment
... The first molecular observation was based on BRCA1 mutations; however, only for a small number of TNBC cases, since at the most only 20% of patients with TNBC have this mutation. 90 91 A proportion of the women with TNBC ...
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Increased macroH2A1.1 expression correlates with poor survival of triple-negative breast cancer patients.
... in breast cancer cell lines on the basis of Affymetrix Human Junction technology ...subtype non claudin-low (non CL) and claudin-low ...subtype non claudin-low (non CL) and ...
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HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer
... were negative for ER and PR, respectively, with com- plete concordance between primary and ...PR negative, respec- ...primary breast tumors and metastases, respectively, had corre- lated ...
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There is no association between microRNA gene polymorphisms and risk of triple negative breast cancer in a Chinese Han population.
... esophageal cancer patients and 346 frequency-matched (age, gender, and ethnicity) controls, seven SNPs in 26 miRNA-related genes were found to be significantly associated with esophageal cancer risk ...and ...
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Androgen receptor expression in triple-negative breast cancer
... on Cancer) is based on all information available prior the first definitive treatment and includes the findings on pathological examination, imaging studies, operative findings on physical examination of the ...
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Inhibition of SK4 Potassium Channels Suppresses Cell Proliferation, Migration and the Epithelial-Mesenchymal Transition in Triple-Negative Breast Cancer Cells.
... for triple-negative breast cancer (TNBC) are limited; intermediate-conductance calcium-activated potassium (SK4) channels are closely involved in tumor progression, but little is known about ...
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Do hereditary syndrome related gynecologic cancers have any specific features 2015
... intraepithelial carcinomas. In addition, these studies failed to identify reproducible precursor lesions in the ovaries [2, 12]. For these reasons, some experts consider ovarian and fallopian tube cancer in ...
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Human REV3 DNA Polymerase Zeta Localizes to Mitochondria and Protects the Mitochondrial Genome.
... Fig 3. Inhibition of OXPHOS increases REV3 expression. (A) RT PCR analysis of Rev3 gene expression in 143B parental and rho° cells. Treatment of 143B parental cells with mitochondrial OXPHOS inhibitors increases ...
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Genomic testing in international guidelines
... Human breast cancer was solely classiied based on clinical and immunohistochemical (IHC) indings in the ...in breast cancer with the uncertain potential of disease spread, such as T1-2, Grade ...
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P02-01. Elicitation of a humoral immune response towards non-immunogenic peptides using the transcriptional transactivator of HIV-1
... S13 Conditional independence relations among biological markers may improve clinical decision as in the case of triple negative breast cancers. Federico M Stefanini, et al[r] ...
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Rev. Bras. Hematol. Hemoter. vol.38 número2
... the breast and, during the patient’s progression, this marker was shown to be positive when immunophenotyping the liquor; this suggests the influ- ence of as yet unknown mechanisms and other ...
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Caracterização da expressão de microRNAS em carcinoma de mama triplo negativo
... Foi demonstrado que o miR 124 tem por alvo diversos genes codificadores, tais como o p38 MAPK, o STAT3 e o AKT2 na via de sinalização EGFR Uhlmann, S. et al. Global microRNA level regulation of EGFR-driven cell-cycle ...
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Depression and Anxiety Disorders among Hospitalized Women with Breast Cancer.
... survivorship trajectory when mental health issues are assessed) [22,33]. In addition, most of the previous studies were based on self-reported questionnaire data rather than diagnostic in- struments [21,24,25,33], and ...
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Rev. Saúde Pública vol.35 número5
... of cancer, such as serum concentration of ...with breast cancer, though slightly reduced the number of eligi- ble controls, seemed to have prevented selection ...
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Long non-coding RNAs as potential therapeutic targets in human breast cancer
... DNA repair (29). Of note, Mdm2 is transcriptionally activated by p53. Alternatively, cells become permanently arrested (senescence) or, when exposed to extensive DNA damage, are directed to apoptosis (23). Apoptosis ...
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PTIP associated protein 1, PA1, is an independent prognostic factor for lymphnode negative breast cancer.
... (GR). Breast cancer is one of the most life threatening diseases for women and has tight association with estrogen and ...invasive breast cancer samples and examined the relationship with ...
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