p53 protein
Histone demethylase Jumonji D3 (JMJD3) as a tumor suppressor by regulating p53 protein nuclear stabilization.
... (direct p53 protein stabilization) mechanism resulting in a p53-mediated cell cycle arrest and ...in p53-mediated differentiation of GSCs and suppression of ...the p53 pathway resulting ...
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Reactivity of p53 protein in canine transmissible venereal tumor
... of p53 protein was evaluated in canine transmissible venereal tumor (CTVT), as following: natural occurrence (n=8); resistant to chemotherapy (n=4); and allogeneic transplanted in progression (n=8), stable ...
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Expression of p53 protein in Barrett’s adenocarcinoma and adenocarcinoma of the gastric cardia and antrum
... of p53 gene mutation and/or protein overexpression, but the influence of the tumour site upon the frequency of p53 protein expression has not been evaluated (gastroesophageal junction, ...
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The expression and significance of p53 protein and Ki-67 protein in pterygium
... as p53, reinforces the hypothesis that the pterygium respresents a lesion similar to tumor 6–9 .... Protein p53 is the guardian of the physical integrity of the cellular genome and inactivation of ...
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Correlation between radiation dose and p53 protein expression levels in human lymphocytes
... of p53 protein expression induced by ionizing radiation presents a dose-dependent pattern correspondent to the amount of DNA breaks induced per unit ...high p53 levels even for lower ...
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Expression of p53 protein in pituitary adenomas
... of p53 protein has seldom been studied in pituitary adenomas and dif- ferent results were obtained in the available ...detect p53 in adenomas and even in pituitary carci- nomas (5,6,10,12), while ...
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Tumor suppressor p53 protein expression : prognostic significance in patients with lowrisk syndrome
... were washed with buffered saline and incubated for 1 h with biotinylated IgG antibody after which the sections were again washed with buffered saline and incubated with the ABC complex (DAKO) for 45 min. The ABC complex ...
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Human papillomavirus infection and p53 protein expression in vulvar intraepithelial neoplasia and invasive squamous cell carcinoma
... the p53 protein, after inhibition of endog- enous peroxidase with 3% hydrogen peroxi- dase in methanol ...for p53) in 10 mM citrate buffer, pH ...
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The expression of p53 protein in patients with multiple myeloma
... proteina p53 zabe ležena je kod 15,52% bolesnika sa novootkrivenim ...ekspresije p53 (do 10% bolesnika) [10, 11, 1316] ili čak izostanak mutacije gena p53 [13] opisani su u studijama koje su ...
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Rev. Col. Bras. Cir. vol.36 número1
... between p53 protein and VEGF expressions and clinicopathological characteristics were assessed by the t- test for continuous variables and by the chi-squared test for categorical ...
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Lysine120 interactions with p53 response elements can allosterically direct p53 organization.
... recruitment. p53-REs are 20-base pair (bp) DNA segments specifying diverse ...the p53 protein recognize a particular p53-RE sequence among all the similar ones? Here, representative ...
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DHT and E2 as modulators of apoptotic signaling in rat Sertoli cells
... apoptotic protein Bax) and leads to the release of these pro-apoptotic factors through the opening of a permeability transition pore (PTP), located in the outer mitochondria membrane (Schmitz, Kirchhoff et ...
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Rev. Bras. Hematol. Hemoter. vol.27 número1
... the p53 protein expression in most cases. Correlations between p53 and the Pgp expression were observed in CML and AML; p53 and MRP in CML, CLL and AML; p53 and Bcl-2 in CML and AML; ...
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Mechanisms that enhance sustainability of p53 pulses.
... triggered p53 pulses by knocking out ...Since p53 also exhibits circadian rhythms at both the mRNA and protein level, various candidate pathways underlying p53 circadian rhythms have been ...
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OTUD5 regulates p53 stability by deubiquitinating p53.
... of p53 is higher in cells transfected with OTUD5 than in cells transfected with empty ...of p53. To this end, 1μg of p53 and increasing amounts of Flag- OTUD5 were cotransfected into H1299 ...in ...
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Braz. Dent. J. vol.16 número1
... In this study, the morphologic analysis of amelo- blastoma cases identified the presence of more than one histologic pattern in the same lesion. PCNA immuno- histochemical expression revealed stronger quantita- tive ...
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Modulation of p53 expression using antisense oligonucleotides complementary to the 5'-terminal region of p53 mRNA in vitro and in the living cells.
... of p53 synthesis was observed for both types of oligomers ...of p53 synthesis resulted from the disturbance of the translation initiation ...of p53 mRNA influenced translation from AUG1 as well ...of ...
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Expressão da proteína p53 em 106 adenomas pleomórficos de glândula salivar maior.
... with p53 protein expression in these ...for p53 protein in 25 out of 106 cases ...of p53 – positive tumors was mainly the ductal type (92%; 23) and cordonal (88%, ...for p53 and ...
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Análise imunohistoquímica da expressão das proteínas p53 e ki67 em adenomas colorretais
... of p53 and Ki-67 proteins in colorectal adenomas, its relations with clinicpathological characteristics and assess the relation between the two ...specific p53 and Ki-67 proteins by enzyme immunoassay ...
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A Bmi1-miRNAs cross-talk modulates chemotherapy response to 5-fluorouracil in breast cancer cells.
... reported p53 could positively regulate miR-200c [27], and here ectopic wild-type p53 expression factually upregulated miR-200c expression in selected cell lines and restored Bmi1 mediated miR-200c ...
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