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PH responsive

pH-responsive artemisinin derivatives and lipid nanoparticle formulations inhibit growth of breast cancer cells in vitro and induce down-regulation of HER family members.

pH-responsive artemisinin derivatives and lipid nanoparticle formulations inhibit growth of breast cancer cells in vitro and induce down-regulation of HER family members.

... The ART Dimer piperazine conjugates (ADPs) designed here were synthesized using lithium bromide (LiBr) as a mild Lewis acid [50] for the epoxide ring opening reaction. This method allowed incorporation of the ...

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Electrochemical Detection of pH-Responsive Grafted Catechol and Immobilized Cytochrome c onto Lipid Deposit-Modified Glassy Carbon Surface

Electrochemical Detection of pH-Responsive Grafted Catechol and Immobilized Cytochrome c onto Lipid Deposit-Modified Glassy Carbon Surface

... this pH- responsive electrophore, the apparent normal potential of the grafted catechol is linearly proportional to the pH with a slope of 60 mV per pH unit over a pH range from 5 to 9 ...

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A pH-responsive drug delivery matrix from an interpolyelectrolyte complex: preparation and pharmacotechnical properties

A pH-responsive drug delivery matrix from an interpolyelectrolyte complex: preparation and pharmacotechnical properties

... Dexibuprofen, also known as (S)-(+)-ibuprofen, is the most active enantiomer of ibuprofen that shows distinct advantages relative to the racemic mixture. The effectiveness of dexibuprofen as an analgesic and anti- ...

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Dual-layered nanogel-coated hollow lipid/polypeptide conjugate assemblies for potential pH-triggered intracellular drug release.

Dual-layered nanogel-coated hollow lipid/polypeptide conjugate assemblies for potential pH-triggered intracellular drug release.

... Distinct from these pioneered studies, a step-by-step polyelec- trolyte deposition technique in combination with in situ covalent crosslinking was used in this work to endow polymeric vesicles with highly biocompatible, ...

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Synthesis and Characterization of pH Stimuli-Responsive Mesoporous Silica Nanoparticles

Synthesis and Characterization of pH Stimuli-Responsive Mesoporous Silica Nanoparticles

... In the field of bionanotechnology, the interest in the development of healthcare devices has increased due to their applications on diagnostics and therapeutics. Mesoporous silica nanoparticles (MSNs) have been used in ...

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Desenvolvimento de novos micro- e nano-sistemas responsivos para entrega de drogas anti-tumorais

Desenvolvimento de novos micro- e nano-sistemas responsivos para entrega de drogas anti-tumorais

... Cancer is a major health care problem with growing incidence, not only at a national level but also worldwide. Due to this urgency in reducing cancer prevalence, the scientific community has put forward a great attention ...

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Functional Stimuli-Responsive Gels: Hydrogels and Microgels

Functional Stimuli-Responsive Gels: Hydrogels and Microgels

... Another class of interesting inorganic materials are quantum dots (QDs), a semiconductor nanostructure that can be used for bioimaging and labeling probes. Their combination with polymer microgels extends the range of ...

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Análise do Desempenho do Protótipo Arduino com Sensor de pH para Medições da Qualidade de Água contaminada em Igarapés de Manaus / PH-Sensor Arduino Prototype Performance Analysis for Measurement of Contaminated Water Quality in Manaus Igarapes

Análise do Desempenho do Protótipo Arduino com Sensor de pH para Medições da Qualidade de Água contaminada em Igarapés de Manaus / PH-Sensor Arduino Prototype Performance Analysis for Measurement of Contaminated Water Quality in Manaus Igarapes

... de pH da água, calibrando com a solução tampão, em que no Sensor de pH utilizou-se o pH=7,0 (neutro), pH=3,0 (ácido) e pH=10 (básico), bem como, coleta de dados, apresentação do método ...

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From natur(e) to architectural matter: responsive shading system

From natur(e) to architectural matter: responsive shading system

... But to get to the ground breaking ecological architecture, we still need to answer some fundamental questions, related to morphological change and time and its correspondent dimension in the architectural field. As ...

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A mutant cell line partially responsive to both IFN- α

A mutant cell line partially responsive to both IFN- α

... sive mutant cell line, B7, which is partially responsive to both IFN- α and IFN- γ . The defect in this mutant was associated with the NRPTK-JAK1, because this cell line is not complemented by fusion with the U4 ...

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Non inflammatory boronate based glucose-responsive insulin delivery systems.

Non inflammatory boronate based glucose-responsive insulin delivery systems.

... In this work, we have screened a library of boronic acid derivatives for toxic and inflammatory properties and identified a lead candidate molecule and several other potential backups that will be better suited for in ...

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Sensing and adaptation to low pH mediated by inducible amino acid decarboxylases in Salmonella.

Sensing and adaptation to low pH mediated by inducible amino acid decarboxylases in Salmonella.

... external pH value, as we just showed in the paragraph ...the pH values of their immediate surrounding, mediated by the activity of the decar- ...external pH values within the range 5-4 [25], and was ...

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Regulation of Autoimmune Neuroinflammation by Stress-responsive Genes

Regulation of Autoimmune Neuroinflammation by Stress-responsive Genes

... case for at least another ubiquitously expressed stress-responsive cytoprotective gene, namely Fth (Fig.1). The mechanism underlying the salutary effect of HO-1 and presumably that of FtH against immune-mediated ...

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High-Throughput Profiling of Caenorhabditis elegans Starvation-Responsive microRNAs.

High-Throughput Profiling of Caenorhabditis elegans Starvation-Responsive microRNAs.

... Also, we confirmed that the expression of three members of the miR-35- 41 family (miR-35-3p, miR-36-3p, and miR-39-3p) was upregulated in 12-hr starved worms, consistent with the RNA-seq[r] ...

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Sorção, dessorção, lixiviação e meia-vida do tebuthiuron em latosolos brasileiros

Sorção, dessorção, lixiviação e meia-vida do tebuthiuron em latosolos brasileiros

... (LVA) pH 5,0 e pH 5,9; Latossolo Vermelho- Amarelo húmico (LVAh) pH 4,8 e pH 5,8; Latossolo Vermelho (LV) pH 5,0 e pH 6,2 e Latossolo Amarelo (LA) pH ...com pH 5,0 ...

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Development of magnetic responsive nanocomposite scaffolds for tendon tissue engineering

Development of magnetic responsive nanocomposite scaffolds for tendon tissue engineering

... Given the superior mechanical performance of woven over braided scaffolds, their biological performance was assessed in terms of tendon-phenotype maintenance and induction of stem[r] ...

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Estudo da pegada hídrica do município de Faro e a sua minimização

Estudo da pegada hídrica do município de Faro e a sua minimização

... a PH global do planeta ...a PH azul, verde e cinzenta da humanidade e mostraram a variabilidade das PH`s nacionais através das tendências de produção e de consumo de alimentos por ...da PH ...

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A nucleotide metabolite controls stress-responsive gene expression and plant development.

A nucleotide metabolite controls stress-responsive gene expression and plant development.

... Many stress-signaling pathways that lead to the activation of stress-responsive genes are dependent on ABA signaling [2,34]. ABI1 is a key component downstream of ABA receptors in the ‘core’ ABA signaling pathway ...

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Transcriptional profiling uncovers a network of cholesterol-responsive atherosclerosis target genes.

Transcriptional profiling uncovers a network of cholesterol-responsive atherosclerosis target genes.

... expanded rapidly, and plateaued after advanced lesions formed. Analysis of lesion expression profiles indicated that accumulation of lipid-poor macrophages reached a point that led to the rapid expansion phase with ...

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K Ca Mg pH

K Ca Mg pH

... of pH, available P, exchangeable K and Mg, and soil moisture content) in MAS occurred because of the relief, even though it influenced the differences between the areas in terms of the stage of natural forest ...

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