Phage therapy
Phage therapy is effective against infection by Mycobacterium ulcerans in a murine footpad model.
... Additionally, phage replication only occurs when the bacterial density is above a certain threshold ...in phage treatment of a local ...about phage therapy is the emergence of ...
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Phage therapy as an approach to prevent Vibrio anguillarum infections in fish larvae production.
... VP-2 phage can protect fish larvae against Vibrio ...the phage resulted in low fish mortality (17%), the survival of infected fish larvae in the presence of the phage increased significantly, ...
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Phage therapy: progress in pharmacokinetics
... of phage therapy depends on enough phage generations in the locality of the target to bring about the eradication of pathogen bacteria from the ...in phage concentration to sufficient ...
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Synergy as a rationale for phage therapy using phage cocktails
... one phage augments the infection properties of a second phage on the same bacterium (which may be contrasted with two phages having somewhat complementary host ...lytic phage, growth is primarily ...
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Pulmonary bacteriophage therapy on Pseudomonas aeruginosa cystic fibrosis strains: first steps towards treatment and prevention.
... Moreover, we observed that bacterial debris released during bacteriophage treatments were not pro-inflammatory, as produc- tion of cytokines was not strongly stimulated in either the curative or the preventive ...
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PARTIAL CHARACTERIZATION OF A LYTIC METHICILLIN RESISTANT-STAPHYLOCOCCUS AUREUS BACTERIOPHAGE
... virulent phage with lytic activity against MRSA strain was ...the phage is member of the family Myoviridae, and exhibited an identical host ...the phage particles contain one major structural protein ...
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The T7-related Pseudomonas putida phage φ15 displays virion-associated biofilm degradation properties.
... to phage therapy, phages with viral- attached EPS depolymerases should therefore preferably be selected for, as they are after all able to break down biofilms by attacking two of their main constituting ...
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Alternatives to overcoming bacterial resistances: State-of-the-art
... of phage host ranges – few strains or species of bacteria – will at a minimum place limitations on presumptive treatment, ...(so-called phage cocktails), the lytic spectrum of phage products can be ...
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Construction of an innocuous Salmonella phage
... for proteins with unknown function. A more thorough analysis of these proteins was completed using HHPred. With Pfam, for protein motif search, an e value threshold of <1x10-5 was always used. The main obtained ...
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CONSTRUÇÃO DE UMA BIBLIOTECA DE ANTICORPOS MONOCLONAIS APRESENTADOS EM FAGOS PARA SELEÇÃO E CARACTERIZAÇÃO DE scFv LIGANTE A PROTEÍNAS INTESTINAIS DE DIATRAEA SACCHARALIS Aluno: Rafael Nascimento
... The sugarcane borer, Diatraea saccharalis (Fabricius, 1794) (Lepidoptera: Crambidae), is the most important insect pest of sugarcane grown in Brazil and others localities in the Americas, causing stalk damage to ...
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Head and Neck Cancer Treatment with Particle Beam Therapy
... hadron therapy which would be more effective and less harmful compared to other forms of radiotherapies used to treat some ...proton therapy both are effective treatments, they have serious differences ...
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The highly virulent 2006 Norwegian EHEC O103:H25 outbreak strain is related to the 2011 German O104:H4 outbreak strain.
... serotypes isolated from patients is not uncommon and has been reported in both O157 and non-O157 isolates [12,29]. In studies where the mechanism of stx gene loss has been investigated, it has been shown that the ...
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IDENTIFICAÇÃO E CARACTERIZAÇÃO DE PEPTÍDEOS MIMÉTICOS DOS ANTÍGENOS DE Mycobacterium leprae POR PHAGE DISPLAY
... M13 phage, using as the ligand target the total purified IgM from leprosy patients of clinical forms, tuberculoid (TT) and lepromatous (LL), and a healthy control ...
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Uso de peptídeo sintético selecionado por Phage Display para imunodiagnóstico da neirocisticercose humana
... Neste trabalho foi selecionado um novo antígeno, através da técnica de Phage Display, para o imunodiagnóstico da neurocisticercose humana. Trata-se de um epitopo que mimetiza um epitopo conformacional que é ...
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UNIVERSIDADE FEDERAL DE UBERLÂNDIA INSTITUTO DE GENÉTICA E BIOQUÍMICA PÓS-GRADUAÇÃO EM GENÉTICA E BIOQUÍMICA ISOLAMENTO E IDENTIFICAÇÃO DE MIMETOPOS DE AUTO-ANTÍGENOS PARA UTILIZAÇÃO EM IMUNODIAGNÓSTICO DA ARTRITE IDIOPÁTICA
... Juvenile Idiopathic Arthritis (JIA) is a set of chronic diseases characterized by persistent inflammation of joints. "Idiopathic" means that no one knows the cause of illness and "Juvenile" in this case ...
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UNIVERSIDADE FEDERAL DE UBERLÂNDIA INSTITUTO DE CIÊNCIAS BIOMÉDICAS PROGRAMA DE PÓS-GRADUAÇÃO EM IMUNOLOGIA E PARASITOLOGIA APLICADAS
... by phage display peptide library specific to IgG present in serum samples from patients with NC and confirm the immunoreactivity from the selected phagetopes in the ELISA test for the diagnosis of human ...
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Determinação de alvos antigênicos na doença reumática cardíaca utilizando phage ...
... "Peptide Phage Display", que permitiu que bibliotecas de phage display fossem amplamente utilizadas na identificação de peptídeos ligantes de virtualmente qualquer alvo biológico, tais como ...
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Caracterização de moléculas envolvidas no desenvolvimento de melanoma pela metodologia de Phage display
... Com o objetivo de identificar modificações na expressão de moléculas em células melan-a após contato com linfócitos B-1 (melan-a transformadas) - potencialmente envolvidas na interação entre células e nas mudanças ...
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Desenvolvimento de anticorpos bi-específicos para o tratamento do VIH-1
... Finalizado o Phage Display, as sequências dos clones VL selecionados foram alinhadas e, posteriormente, determinada a sua similaridade. A partir desta análise e, tendo em conta todas as sequências obtidas, foi ...
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Development of a multifunctional phage-based nanoparticle for targeted drug delivery
... contrary, phage amplification is a limited process during stationary phase, where anaerobic bacterial respiration takes place ...M13KE phage has the lacZ alpha gene fragment (lacZα), its host bacteria have ...
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