proinflammatory cytokine
Human resistin is a systemic immune-derived proinflammatory cytokine targeting both leukocytes and adipocytes.
... The characteristics of human resistin (RETN) are unclear and controversial despite intensive adipose-focused research. Its transcriptional and functional similarity with the murine myeloid-specific and CCAAT/enhancer ...
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Long-time treatment by low-dose N-acetyl-L-cysteine enhances proinflammatory cytokine expressions in LPS-stimulated macrophages.
... of proinflammatory cytokine expressions by short-time NAC treatment at a low-concentration is caused by an indirect effect of p53 inhibiting transcriptional activity of ...
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Role of PAF receptor in proinflammatory cytokine expression in the dorsal root ganglion and tactile allodynia in a rodent model of neuropathic pain.
... these proinflammatory cytokines and regulate pain signaling [49,50,51,52], although it remains unknown whether PAFR activation leads to upregulation of proinflammatory cytokine expression in ...
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Rhoifolin regulates oxidative stress and proinflammatory cytokine levels in Freund’s adjuvant-induced rheumatoid arthritis via inhibition of NF-κB
... This study was taken to identify the effect of rhoifolin on complete Freund ’s adjuvant (CFA)-induced arthritis in the rat model.. Treatment with rhoifolin (10 and 20 mg/kg) showed a sig[r] ...
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Natalizumab Therapy Modulates miR-155, miR-26a and Proinflammatory Cytokine Expression in MS Patients.
... Th1/Th17 cytokine types such as IL-17a, IFN γ, TNFα but not IL-6, whereas the second MS group charac- terized by high levels of miR-26a, over-expressed only Th1 cytokine types such as IFN γ and ...
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Inhibitors of MyD88-dependent proinflammatory cytokine production identified utilizing a novel RNA interference screening approach.
... To determine if these shRNA sequences targeted genes necessary for the induction of proinflammatory cytokines, we generated lentiviruses containing these hairpin sequences and tested them individually in the ...
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Primary dengue virus infections induce differential cytokine production in Mexican patients
... of proinflammatory cytokines have been associ- ated with dengue disease ...the cytokine levels in 171 sera from Mexican patients with primary den- gue fever (DF) and dengue haemorrhagic fever (DHF) from ...
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Zoledronic acid enhances lipopolysaccharide-stimulated proinflammatory reactions through controlled expression of SOCS1 in macrophages.
... However, cytokine levels and nitric oxide (NO) production increased after pretreatment with ...of cytokine signaling-1 (SOCS1), which is a negative regulator of myeloid differentiation primary response gene ...
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DEXAMETHASONE ALTERS THE CYTOKINE PROFILE 20 03 2008
... Interleukin IL-6 mRNA changes significantly (p<0,05) in DEX animals in antrum region. Interleukin-6 (IL-6) is proinflammatory cytokine that produces multifunctional effects. It is involved in the ...
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Cytokine pro file and lymphocyte subsets in type 2 diabetes
... the cytokine profile in newly-diagnosed T2D patients at pre- and post-metformin treatment and showed decreased serum IL-17 levels, but no changes in IFN-g levels ...
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Cytokine-based log-scale expansion of functional murine dendritic cells.
... of cytokine/chemokines in response to stimulators, including the F-gene deleted non-transmissible recombinant Sendai virus (SeV/dF) recognized by RIG-I [4,11], LPS by Toll-like receptor 4 (TLR-4), poly I:C by ...
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Serum cytokine levels in autoimmune and non-autoimmune hyperthyroid states
... measurable cytokine could be of help in the not infrequent situation in which clini- cal evaluation and laboratory data are insuf- ficient to distinguish GD from other hyper- thyroid ...
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Serum cytokine profile in the subclinical form of visceral leishmaniasis
... macrophage-stimulating cytokine pro- file (Th1 profile) including interferon-gamma (IFN-γ) and interleukins (IL)-2 and -12, while, on the other hand, an elevated production of immunosuppressive cytokines such as ...
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Mental quality of life is related to a cytokine genetic pathway.
... SNPs in IL4R Gene Correlate with Mental Quality of Life As mental QoL was associated with the expression of cytokine genes, we selected SNPs in 88 cytokine-related genes and 2 kb up- and down-stream of ...
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Epigenetic and transcriptional signatures of stable versus plastic differentiation of proinflammatory gd T cell subsets
... spontaneous cytokine secretion after activation, in contrast to the delayed differ- entiation of conventional CD4 + T cells of the T H 1 or T H 17 subset of helper T cells 15 ...
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Cytokine profile associated with chronic and acute human schistosomiasis mansoni
... the cytokine IFN-γ was neutral- ized by antibodies against this cytokine and its receptor (αIFNγ/IFNγR, 7 ...the cytokine IL-13, we added recombinant IL-13 (rIL-13) to the cultures so that the final ...
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Plasma cytokine expression is associated with cardiac morbidity in chagas disease.
... of cytokine production observed in these ...plasma cytokine levels in well- defined clinical polar groups of chagasic patients divided into categories that better reflect the wide cytokine profile ...
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Peripheral cytokine and chemokine alterations in depression : a metaanalysis of 82 studies
... Cytokines and chemokines have been classically subdivided as anti-inflammatory and proinflamma- tory. However, emerging evidence indicates that this subdivision may be overly simplistic. For example, IL-6 may activate a ...
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The effects of propolis on cytokine production in lipopolysaccharide-stimulated macrophages
... Lippolisakkarit ve propolis’in U937 hücrelerinde IL-1β üretimine etkisi (M, sadece makrofaj içeren kuyucuk; M+L, makrofaj hücreleri ve LPS içeren kuyucuk; M+L+P, makrofaj hücreleri + LP[r] ...
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Structural and conformational effects of metal binding to the S100B cytokine
... In order to investigate the effect of metal ion binding on the structure of S100B, the wild type (wt ) and a cysteine-to-serine mutant, ∆Cys protein, were studied in apo (metal free) and[r] ...
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