Promoter Region
Single nucleotide polymorphisms of PIN1 promoter region and cancer risk: evidence from a meta-analysis.
... (2667T.C rs2233679, 2842G.C rs2233678) in the promoter region of PIN1 have been mostly investigated. In 2007, Segat and colleagues [21] found the 2667T.C polymorphism was associ- ated with hepatocelluar ...
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Identification of a single-nucleotide insertion in the promoter region affecting the sodC promoter activity in Brucella neotomae.
... of region upstream to the sodC gene identified a single-nucleotide insertion in the potential promoter ...sodC promoter of ...sodC promoter activities using translational fusion constructs ...
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Rarity of DNA sequence alterations in the promoter region of the human androgen receptor gene
... Blood samples were obtained from 100 healthy male blood donors at Hemocentro, State University of Campinas, Campinas, SP, Brazil. The ages of these individuals ranged from 18 to 58 years (mean ± SD: 36.6 ± 9.7 years). ...
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Computational characterization of modes of transcriptional regulation of nuclear receptor genes.
... It has been shown earlier that GRB target genes often have higher ratios between CpG island length and transcript length [25]. In contrast to most other genes, CpG islands in GRB target genes not only cover the ...
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Systematic functional study of cytochrome P450 2D6 promoter polymorphisms in the Chinese Han population.
... The promoter polymorphisms of drug-metabolizing genes can lead to interindividual differences in gene expression, which may result in adverse drug effects and therapeutic ...the promoter region and ...
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Importância de polimorfismos de genes reguladores de citocinas em transplantes de células progenitoras hematopoiéticas.
... Polymorphisms in the TNFA gene promoter region show evidence of strong linkage disequilibrium with HLA and are associated with delayed neutrophil engraftment in unrelated donor hematopoi[r] ...
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Cross species association examination of UCN3 and CRHR2 as potential pharmacological targets for antiobesity drugs.
... the promoter polymorphisms affect transcriptional regulatory binding sites and how coding polymorphisms have an impact on the mRNA secondary ...the promoter region of the bovine UCN3 gene, four ...
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Correlation between the BACTEC MGIT 960 culture system with Genotype MTBDRplus and TB-SPRINT in multidrug resistant
... RRDR region of the genes rpoB, katG and the inhA promoter region of the five clinical isolates, with discordant results for RIF and INH, identified two as being drug susceptible, two as RIF resistant ...
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J. Appl. Oral Sci. vol.18 número5
... Two fragments of the promoter region were cloned on reporter plasmids containing the luciferase gene and transfected into three different rat embryo tissues: digits, face and midbrai[r] ...
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Genetic characterisation of Langerin gene in human immunodeficiency virus-1-infected women from Bahia, Brazil
... Study patients - HIV-1-infected women - The pro- moter and CRD-encoding regions of the Langerin gene were studied in convenience samples of 116 and 118 HIV-1-infected women, respectively, who were re- cruited during a ...
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A review of psychiatric genetics research in the Brazilian population
... Analysis of a novel functional polymorphism within the promoter region of the serotonin transporter gene (5-HTT) in Brazilian patients affected by bipolar disorder and schizop[r] ...
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Análise da variabilidade genética e expressão de HPV em papilomatose de laringe
... The promoter region LCR (Long Control Region) contains cis-regulatory elements for cellular and viral transcription factors (TF) that control viral early gene expression and ...in promoter ...
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Rev. Bras. Hematol. Hemoter. vol.36 número1
... the promoter region and exon 1 of the MBL2 gene are correlated with MBL protein serum levels and, consequently, associated to a higher risk for the development of infectious ...gene-coding region are ...
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Identification of RegIV as a novel GLI1 target gene in human pancreatic cancer.
... RegIV promoter domain containing GLI1 motifs in immunoprecipitated DNA was identified by PCR using the following primers: RegIV-A for site 1 (118 bp), forward: 59-5-TGGTCCCTTCCAGACTTA-3-39, re- verse: 5 9- ...
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Estudo de associação entre genes do sistema dopaminérgico e esquizofrenia
... Analysis of a novel functional polymorphism within the promoter region of the serotonin transporter gene (5-HTT) in Brazilian patients affected by bipolar disorder and schizophrenia. A[r] ...
203
Loss of Expression of Reprimo, a p53-induced Cell Cycle Arrest Gene, Correlates with Invasive Stage of Tumor Progression and p73 Expression in Gastric Cancer.
... by promoter methylation, although it has been weakly correlated with its expression ...its promoter region methylation status, suggesting epigenetic si- lencing of RPRM gene ...
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O papel do polimorfismo funcional VNTR da região promotora do gene MAOA nos transtornos psiquiátricos
... the promoter region of the monoamine oxidase A (MAOA) gene has been described and many studies have investigated the association of this polymorphism with human behaviors, as well as with several ...
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Rev. Bras. Psiquiatr. vol.31 número2
... Objective: Evidence from family and molecular genetic studies support the hypothesis of involvement of immunologic mechanisms in the pathophysiology of obsessive-compulsive disorder. The nuclear factor of kappa light ...
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Darier disease: molecular study of a two-generation Portuguese family
... Future perspectives would involve sequencing the promoter region of ATP2A2 gene in order to examine whether other variants could explain the wild-type SERCA2 mRNA expression[r] ...
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A CRE/AP-1-like motif is essential for induced syncytin-2 expression and fusion in human trophoblast-like model.
... forskolin-responsive region (150 bp) or the 600 bp promoter region equally reduced their responsiveness toward ...forskolin-induced promoter activity upon specific mutation of this ...
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