Protease inhibitor
HIV-1 Genotypes Related to Failure of Nelfinavir as the First Protease Inhibitor Treatment
... first protease inhibitor in our setting became ...of protease gene mutations, detection of mutations related to nucleosides (NAM) and the time of use of ARV, and the number of secondary mutations and ...
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A Treatment with a Protease Inhibitor Recombinant from the Cattle Tick (Rhipicephalus Boophilus microplus) Ameliorates Emphysema in Mice
... serine protease inhibitor is a canonical inhibitor of serine proteases which domain has molecular mass around 7000 Da with three disulfide bridges, characterizing a protein with a stabilized ...
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The effect of an HIV-1 viral protease inhibitor on staurosporine-induced apoptosis in immortalized mesangial cells
... HIV-1 protease inhibitor Ac-Leu-Val-phenylalanine (PI; Calbiochem, CA, USA) on the rate of staurosporine-induced apoptosis was then ...iii) protease inhibitor (900 nM – this concentration is ...
3
Functional analysis of a missense mutation in the serine protease inhibitor SPINT2 associated with congenital sodium diarrhea.
... serine protease inhibitor Hepatocyte Growth Factor Inhibitor HAI-2 is associated with a congenital sodium ...potent inhibitor of nine gastro-intestinal serine ...
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The first serine protease inhibitor from Lasiodora sp (Araneae: Theraphosidae) hemocytes
... The final purification of EILaH was obtained by a reversed phase chromatography and the homogeneity of preparation was demon- strated by detection of a single peptide on SDS-PAGE and a single molecular mass by MALDI-TOF, ...
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In vitro ANTIGIARDIAL ACTIVITY OF THE CYSTEINE PROTEASE INHIBITOR E-64
... this protease inhibitor in ...on protease inhibitors targeting parasite cysteine proteases open perspectives for future investigations in order to confirm the real antigiardial potential of E-64 and ...
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Frequência de tabagismo e das mutações N34S e P55S do gene Serine Protease Inhibitor...
... Em 2000, a análise de pacientes com pancreatite, nos quais não foram identificadas mutações no gene PRSS1, permitiu a identificação da mutação N34S no exon 3 do gene SPINK1 (serine protease inhibitor Kazal ...
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Virologic failure of protease inhibitor-based second-line antiretroviral therapy without resistance in a large HIV treatment program in South Africa.
... Methodology/ Principal Findings: HIV-infected patients $15 years of age who had failed protease inhibitor (PI)-based second-line ART (2 consecutive HIV RNA tests .1000 copies/ml on lopinavir/ritonavir, ...
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Quantitative proteomic analysis of oral brush biopsies identifies secretory leukocyte protease inhibitor as a promising, mechanism-based oral cancer biomarker.
... leukocyte protease inhibitor (SLPI) protein stood out based on its decrease in abundance in both OPML and OSCC lesion tissues compared to healthy normal ...
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Tryptogalinin is a tick Kunitz serine protease inhibitor with a unique intrinsic disorder.
... b-tryptase inhibitor from the hard tick Rhipicephalus appendiculatus ...Kunitz protease inhibitors, but unlike TdPI, tryptogalinin possesses six Cys residues forming three disulfide ...the inhibitor ...
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A cysteine protease inhibitor of plasmodium berghei is essential for exo-erythrocytic development.
... this inhibitor during the blood ...this inhibitor during the blood stage as ...the inhibitor was high and the obtained knockout clones may have carried modifications in addition to the pbicp ...
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Rmcystatin3, a cysteine protease inhibitor from Rhipicephalus microplus hemocytes involved in immune response
... The Rhipicephalus microplus tick is responsible for losses in the livestock production estimated in 2 billions USD. Despite its economical importance the knowledge in tick's physiology is sparse. In order to contribute ...
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Liver safety of two nucleoside analogs plus efavirenz, nevirapine or a ritonavir-boosted protease inhibitor in HIV/HCV-coinfected drug-naïve patients
... Driven by the European AIDS Treatment Group (EATG) and Community recommendations on universal access to HIV services for migrants and ethnic minorities in Europe, this session will add[r] ...
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Bowman-Birk protease inhibitor from Vigna unguiculata seeds enhances the action of bradykinin-related peptides
... in protease inhibitors has focused on natural inhibitors from different sources, particularly leguminous plants that are capable of regulating a number of relevant biological ...Bowman-Birk Inhibitor (BBI) ...
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Tigutcystatin, a cysteine protease inhibitor from Triatoma infestans midgut expressed in response to Trypanosoma cruzi
... of T. infestans T. cruzi – infected (Fig. 4B). These results suggested more than one role of this molecule in T. infestans. Since triatomine insects use cathepsins for protein digestion in posterior midgut [27], ...
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Effect of Natural Polymorphisms in the HIV-1 CRF02_AG Protease on Protease Inhibitor Hypersusceptibility
... the protease coding region of a non-B HIV-1 subtype linked to protease inhibi- tor HS, namely, 17E and 64M in ...specific protease inhibitors such as amprenavir and atazanavir, but the combination of ...
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Randomized trial of time-limited interruptions of protease inhibitor-based antiretroviral therapy (ART) vs. continuous therapy for HIV-1 infection.
... Genotypic Resistance Testing. Viral RNA was extracted from plasma using the QIAamp Viral RNA Mini kit (QIAGEN Group, Germany). RNA extractions were incubated at 37 uC for 2 hours with 1–5 U Heparinase (Sigma Aldrich) and ...
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Potential elucidation of a novel CTL epitope in HIV-1 protease by the protease inhibitor resistance mutation L90M.
... HIV protease inhibitors (PI) and HIV reverse transcriptase inhibitors (RTI) inhibit steps in the HIV-1 viral replication cycle and have a large negative impact on viral load ...
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Clonagem, expressão e caracterização de um inibidor de tripsina presente no mosquito Aedes aegypti
... trypsin inhibitor from the Aedes aegypti ...serine protease inhibitor, in female salivary glands, carcass and also in whole male, which we named AaTI ...serine protease inhibitor from ...
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