• Nenhum resultado encontrado

Protein-protein interaction

Identification of colorectal cancer related genes with mRMR and shortest path in protein-protein interaction network.

Identification of colorectal cancer related genes with mRMR and shortest path in protein-protein interaction network.

... functional protein association ...existing protein-protein interaction data from STRING (Search Tool for the Retrieval of Interacting Genes), a weighted functional protein association ...

12

Construction and analysis of the protein-protein interaction networks based on gene expression profiles of Parkinson's disease.

Construction and analysis of the protein-protein interaction networks based on gene expression profiles of Parkinson's disease.

... and protein-protein interaction (PPI) databases were combined to construct the PPI networks of differentially expressed (DE) genes in post mortem brain tissue samples of patients with Parkinson’s ...

17

Sequence motifs in MADS transcription factors responsible for specificity and diversification of protein-protein interaction.

Sequence motifs in MADS transcription factors responsible for specificity and diversification of protein-protein interaction.

... domain protein-protein interactions, our IMSS method can be used to predict MADS domain interactomes for other plant ...experimental protein-protein interaction data are available ...

13

Identification of significant pathways in gastric cancer based on protein-protein interaction networks and cluster analysis

Identification of significant pathways in gastric cancer based on protein-protein interaction networks and cluster analysis

... Gastric cancer is one of the most common and lethal cancers worldwide. However, despite its clinical importance, the regulatory mechanisms involved in the aggressiveness of this cancer are still poorly understood. A ...

202

Inference of gene-phenotype associations via protein-protein interaction and orthology.

Inference of gene-phenotype associations via protein-protein interaction and orthology.

... as protein-protein interaction (PPI) data [6–12], sequence data [13,14] and function annotations [15–19]) have been used to identify gene-phenotype ...

8

Predicting Pharmacodynamic Drug-Drug Interactions through Signaling Propagation Interference on Protein-Protein Interaction Networks.

Predicting Pharmacodynamic Drug-Drug Interactions through Signaling Propagation Interference on Protein-Protein Interaction Networks.

... another protein within the same pathways [7, ...human protein interaction networks, Human Protein Reference Database (HPRD) (9,117 proteins and 36,248 interactions), Interologous ...

13

Protein-protein interaction analysis highlights additional loci of interest for multiple sclerosis.

Protein-protein interaction analysis highlights additional loci of interest for multiple sclerosis.

... a protein-protein interaction (PPI) analysis of gene products coded in loci recently reported to be MS associated at the genome-wide significance level and in loci suggestive of MS ...Association ...

7

DUF581 is plant specific FCS-like zinc finger involved in protein-protein interaction.

DUF581 is plant specific FCS-like zinc finger involved in protein-protein interaction.

... the protein-protein interaction with the prey proteins suggesting their role in protein-protein interaction (Figure ...of interaction compared to full length bait while ...

11

Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions

Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions

... relative protein abundance, mRNA processing, stoichiometry and interaction kinetics, complex formation and posttranslational ...known interaction dynamics between components of the circadian system ...

14

Predicting protein phenotypes based on protein-protein interaction network.

Predicting protein phenotypes based on protein-protein interaction network.

... seed protein YBR039W with the other seed proteins are listed in Table ...that protein YBR039W and its neighbors YBL099W, YDL004W, YDR298C, YLR295C, YML081C-A, YPL078C, YPL271W are members of the same F0/F1 ...

8

A network-based gene expression signature informs prognosis and treatment for colorectal cancer patients.

A network-based gene expression signature informs prognosis and treatment for colorectal cancer patients.

... Consistent with previous reports [10], we found minimal overlap among these gene expression signatures at individual gene level (Figure 2). To test whether these signatures converge at common biological processes, we ...

13

Investigating ego modules and pathways in osteosarcoma by integrating the EgoNet algorithm and pathway analysis

Investigating ego modules and pathways in osteosarcoma by integrating the EgoNet algorithm and pathway analysis

... background protein-protein interaction (PPI) network (PPIN) based on gene expression data and PPI data; extracting differential expression network (DEN) from the background PPIN; identifying ego ...

7

A novel human tectonin protein with multivalent beta-propeller folds interacts with ficolin and binds bacterial LPS.

A novel human tectonin protein with multivalent beta-propeller folds interacts with ficolin and binds bacterial LPS.

... b-propeller protein, in accordance to the definition of the Tectonin ...in protein-protein interaction amongst host proteins and also in pathogen- detection, thus playing a vital role in ...

9

Mutational robustness of gene regulatory networks.

Mutational robustness of gene regulatory networks.

... a protein-protein interaction change, where a dimer A–B is changed to dimer A–C (that did not occur yet in the protein-protein interaction ...the protein-protein ...

9

A computational method based on the integration of heterogeneous networks for predicting disease-gene associations.

A computational method based on the integration of heterogeneous networks for predicting disease-gene associations.

... which protein-protein interaction data have been exploited to identify disease-causing genes, based on the observation that genes implicated in a specific or similar diseases tend to be located in a ...

10

Gene expression pro filing analysis of lung adenocarcinoma

Gene expression pro filing analysis of lung adenocarcinoma

... and protein-protein interaction (PPI) networks obtained from the STRING database were constructed with ...receptor protein signaling pathway (MAPK1, STAT3, RAF1, and JAK1), and regulation of ...

11

Targeting protein-protein interactions for parasite control.

Targeting protein-protein interactions for parasite control.

... the protein-protein ...main protein catagories: G-protein coupled receptors (GPCRs), serine/ threonine and tyrosine protein kinases, zinc metallopeptidases, serine proteases, nuclear ...

12

Composition of Overlapping Protein-Protein and Protein-Ligand Interfaces.

Composition of Overlapping Protein-Protein and Protein-Ligand Interfaces.

... of protein interfaces to those of overlapping pro- tein-ligand interfaces should aid in targeting protein-protein interaction ...for protein interfaces and ...

18

Neighbor overlap is enriched in the yeast interaction network: analysis and implications.

Neighbor overlap is enriched in the yeast interaction network: analysis and implications.

... such protein pairs to the high NO enrichment, we removed all pairs reported to be in the same complex ...all protein pairs that were reported by Pu et ...that protein complexes were not the only ...

9

Recovering protein-protein and domain-domain interactions from aggregation of IP-MS proteomics of coregulator complexes.

Recovering protein-protein and domain-domain interactions from aggregation of IP-MS proteomics of coregulator complexes.

... direct protein-protein interac- tions between prey proteins without considering the specific ...the protein-protein interac- ...known protein-protein and domain-domain ...

10

Show all 7200 documents...

temas relacionados