Protein-protein interactions
The Development of a Universal In Silico Predictor of Protein-Protein Interactions
... of Protein-Protein Interactions (UNISPPI), an ML-based approach that use features associated with amino acid sequences for building models for predicting ...non-interacting protein pairs ...
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Protein-protein interactions within late pre-40S ribosomes.
... their protein and RNA composition. Here, we have analyzed the protein-protein interactions between the seven assembly factors bound to late cytoplasmic pre-40S ribosomes using recombinant ...
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A Library of Plasmodium vivax Recombinant Merozoite Proteins Reveals New Vaccine Candidates and Protein-Protein Interactions.
... novel protein-protein interactions, confirming that the proteins are functional and further supporting their potential as vaccine ...recombinant protein library will facilitate future studies ...
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Wiki-pi: a web-server of annotated human protein-protein interactions to aid in discovery of protein function.
... Protein-protein interactions (PPIs) are the basis of biological ...the interactions of a protein can help understand its molecular function and its association with different biological ...
10
Intragenic suppressor of Osiaa23 revealed a conserved tryptophan residue crucial for protein-protein interactions.
... the protein-protein interactions between Osiaa23 and ...(C-D) Interactions between Osiaa23 and OsARFs, Osiaa23 and OsARF(WS)s in the yeast two-hybrid ...the protein-protein ...
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Identification of novel protein-protein interactions of Yersinia pestis type III secretion system by yeast two hybrid system.
... potential protein-protein interactions, which is designated as forward ...the interactions were screened out repeatedly in different rounds of experiment and totally 21 pairs of ...
9
Cooperative DNA Recognition Modulated by an Interplay between Protein-Protein Interactions and DNA-Mediated Allostery.
... direct interactions or DNA-mediated ...of protein-DNA unbinding and free energy profiling to study the cooperative DNA recognition by OCT4 and SOX2, key components of enhanceosomes in pluripotent ...between ...
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Interface-resolved network of protein-protein interactions.
... combined with homology modeling [5], genomic data [19], and docking algorithms [20–22], to both assign and infer [23] binding interfaces. While it would be possible to construct an IIN from the residue level details ...
14
Identification of an FHL1 protein complex containing gamma-actin and non-muscle myosin IIB by analysis of protein-protein interactions.
... modular protein binding interface to mediate protein-protein ...the interactions of FHL1 could provide important new insights into its functional role in both skeletal muscle development and ...
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Protein-protein interactions in clathrin vesicular assembly: radial distribution of evolutionary constraints in interfaces.
... adaptor protein, across eukaryotes, despite the differences in the nature of ...their protein-protein interactions through the tandem repeat ...
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Targeting protein-protein interactions for parasite control.
... via interactions with other proteins, so protein-protein interactions (PPIs) offer a realm of unexplored potential drug targets and are thought to be the next-generation of drug ...few ...
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Protein-protein interactions as a strategy towards protein-specific drug design: the example of ataxin-1.
... in protein-protein interactions with other partners ...the protein, which has been proposed to play a ‘dual’ role in regulation of transcription and RNA-processing and/or metabo- lism ...
9
Diversity of T cell epitopes in Plasmodium falciparum circumsporozoite protein likely due to protein-protein interactions.
... inter-molecular interactions of the intact protein are likely key to the observed diversity, it does not exclude a role for the T cell responses that have been observed in exposed ...Intermolecular ...
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A flow cytometry-based FRET assay to identify and analyse protein-protein interactions in living cells.
... interactions with cellular factors [21]. Lentiviral Nef and Vpu proteins are important for efficient viral replication and AIDS progression in vivo [15]. While it has been established that Nef and Vpu manipulate ...
10
The many faces of protein-protein interactions: A compendium of interface geometry.
... Only a small fraction of family pairs appeared both in fused and separate forms in PQS (Table 4). In screening non- genuine fusions, we also filtered out PQS entries containing both intra- and inter-type interfaces of a ...
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Predicting Protein-Protein Interactions Using BiGGER: Case Studies
... general, protein docking algorithms aim to predict the structure of a complex from the structure of the partners with the assumption that there is one correct structure for the complex, as seems to be the case for ...
19
Sequence motifs in MADS transcription factors responsible for specificity and diversification of protein-protein interaction.
... molecular interactions, which in turn determine biological functions of ...how protein sequences define interaction specificity is largely missing, in particular for paralogous protein families with ...
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A viral-human interactome based on structural motif-domain interactions captures the human infectome.
... literature-curated interactions, and the dataset produced by Jager et ...contains interactions from an affinity binding and purification mass spectrometry (AP-MS) ...at protein or domain level, thus ...
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Composition of Overlapping Protein-Protein and Protein-Ligand Interfaces.
... over-represented interactions were found between the pairs of trypto- phan ...over-represented interactions were pairs of tryptophan ...of protein-protein interfaces that reported an ...
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R OCHA DEA LMEIDA
... in protein structure ...alter protein stability and ...of protein structure in order for its effects to be ...transient protein-protein interactions (reviewed in ...of ...
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