serine protease inhibitor
Functional analysis of a missense mutation in the serine protease inhibitor SPINT2 associated with congenital sodium diarrhea.
... Membrane-bound serine proteases play important roles in different biological ...the serine protease inhibitor Hepatocyte Growth Factor Inhibitor HAI-2 is associated with a congenital ...
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Frequência de tabagismo e das mutações N34S e P55S do gene Serine Protease Inhibitor...
... Em 2000, a análise de pacientes com pancreatite, nos quais não foram identificadas mutações no gene PRSS1, permitiu a identificação da mutação N34S no exon 3 do gene SPINK1 (serine protease inhibitor ...
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The first serine protease inhibitor from Lasiodora sp (Araneae: Theraphosidae) hemocytes
... The final purification of EILaH was obtained by a reversed phase chromatography and the homogeneity of preparation was demon- strated by detection of a single peptide on SDS-PAGE and a single molecular mass by MALDI-TOF, ...
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Tryptogalinin is a tick Kunitz serine protease inhibitor with a unique intrinsic disorder.
... b-tryptase inhibitor from the hard tick Rhipicephalus appendiculatus ...Kunitz protease inhibitors, but unlike TdPI, tryptogalinin possesses six Cys residues forming three disulfide ...targeted ...
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Identification and characterization of fusolisin, the Fusobacterium nucleatum autotransporter serine protease.
... A serine endopeptidase of 61–65 kDa capable of damaging host tissue and of inactivating immune effectors was detected previously in ...this serine protease, named fusolisin, in three oral ...the ...
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Clonagem, expressão e caracterização de um inibidor de tripsina presente no mosquito Aedes aegypti
... trypsin inhibitor from the Aedes aegypti ...Kazal-type serine protease inhibitor, in female salivary glands, carcass and also in whole male, which we named AaTI ...inhibitors, serine ...
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Plasminogen activator inhibitor 1 and Antipain preserve acrosome integrity of bovine spermatozoa during cryopreservation
... of serine protease inhibitors over the acrosome reaction during in vitro fertilization of rats (Honda et ...of serine protease the acrosome reaction did not occur (Pillai and Meizel, ...
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Interaction of protein C inhibitor with the type II transmembrane serine protease enteropeptidase.
... C inhibitor (PCI) is a serine protease inhibitor and a member of the serpin superfamily ...plasma inhibitor of activated protein C (APC) ...the protease. The protease ...
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RICARDO ANDRADE BARATA,’ MILTON HERCULES GUERRA ANDRADE,2
... The purified enzyme was strongly inhibited by 4- (2-aminoethyl)-benzenesulfonyl fluoride hydrochloride (PEFABLOC), an irreversible serine protease inhibitor, pAB, and [r] ...
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Potential elucidation of a novel CTL epitope in HIV-1 protease by the protease inhibitor resistance mutation L90M.
... HIV protease, occurs at lower frequencies in hosts that harbor the B*15, B*48 or A*32 human leukocyte antigen ...HIV protease region, PR 89–97 and PR 90–99 to HLA-B*15/ B*48 and HLA-A*32 respectively due to ...
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Crystallization of bothrombin, a fibrinogen-converting serine protease isolated from the venom of Bothrops jararaca
... Intravenous injection of these thrombin-like enzymes causes rapid de®brinogenation arising from the proteolysis of ®brinogen, forming non-crosslinked ®brin monomers which are removed rapidly from circulation. Because of ...
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In vitro ANTIGIARDIAL ACTIVITY OF THE CYSTEINE PROTEASE INHIBITOR E-64
... that growth was not affected by E-64d up to 50 µM. In addition, according to this author, the survival of trophozoites in the presence of this inhibitor did not differ from that observed in the untreated cultures. ...
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A cysteine protease inhibitor of plasmodium berghei is essential for exo-erythrocytic development.
... and hence connects to myosin A [42,43]. The forward motion of sporozoites results from the posterior translocation of the substrate-TRAP-motor complex assembly. Drug treatments, mutations of the motility machinery, or ...
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A multifunctional serine protease primes the malaria parasite for red blood cell invasion
... of protease inhibitors to inactivate endogenous proteases, including PfSUB1, as completely as ...selective inhibitor of PfSUB1 (Jean et al, 2003), suggesting that it was mediated by residual endogen- ous ...
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Kinetic characterization of gyroxin, a serine protease from Crotalus durissus terrificus venom
... This work describes for the first time the characterization of the enzymatic features of gyroxin, a serine protease from Crotalus durissus terrificus venom, capable to induce barrel rotation syndrome in ...
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Assessment and partial purification of serine protease inhibitors from Rhipicephalus (Boophilus) annulatus larvae
... Serine protease inhibitors are classified into at least 18 families based on the primary and three-dimensional structures and inhibition mechanisms (LASKOWSKI; QASIM, ...purified serine ...
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Proteases of haematophagous arthropod vectors are involved in blood-feeding, yolk formation and immunity - a review
... distinct routes, the proteolytic system that controls the albuminolytic and haemoglobinolytic pathways is the same [38]. A multi-enzyme model for Hb degradation was proposed in Ixodes ricinus. Inside the acidic digest- ...
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Characterization of ß-trypsin at acid pH by differential scanning calorimetry
... a serine protease since it exhibits 223 amino acid residues that are presented in two similar domains (4), its three-dimensional structure is known, it possesses high reversibility for the type of ...
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Rmcystatin3, a cysteine protease inhibitor from Rhipicephalus microplus hemocytes involved in immune response
... shown. Protease inhibitors also participate in tick immunity [19,20] among them, a type-2 cystatin from Haemaphysalis longicornis was able to inhibit the in vitro growth of Babesia gibsoni ...
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