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Stem Cell Factor

Cloning of Soluble Human Stem Cell Factor in pET-26b(+) Vector

Cloning of Soluble Human Stem Cell Factor in pET-26b(+) Vector

... Purpose: Stem cell factor (SCF) plays an important role in the survival, proliferation and differentiation of hematopoietic stem cells and progenitor ...hematopoietic stem cell ...

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Stem cell factor protects against neuronal apoptosis by activating AKTERK in diabetic mice

Stem cell factor protects against neuronal apoptosis by activating AKTERK in diabetic mice

... Neuronal apoptosis occurs in the diabetic brain due to insulin deficiency or insulin resistance, both of which reduce the ex- pression of stem cell factor (SCF). We investigated the possible ...

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Membrane-to-nucleus signaling links insulin-like growth factor-1- and stem cell factor-activated pathways.

Membrane-to-nucleus signaling links insulin-like growth factor-1- and stem cell factor-activated pathways.

... Stem cell factor (mouse: Kitl, human: KITLG) and insulin-like growth factor-1 (IGF1), acting via KIT and IGF1 receptor (IGF1R), respectively, are critical for the development and integrity of ...

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Regulation of stem cell factor expression in inflammation and asthma

Regulation of stem cell factor expression in inflammation and asthma

... Stem cell factor (SCF) is a major mast cell growth factor, which could be involved in the local increase of mast cell number in the asthmatic ...mast cell number in the ...

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Stem cell factor expression after renal ischemia promotes tubular epithelial survival.

Stem cell factor expression after renal ischemia promotes tubular epithelial survival.

... magnification: 106. (B) Double immunostaining for CD10 (blue) and c-KIT (red) demonstrates that proximal tubules expressing CD10 located in the corticomedullary area do not express c-KIT (indicated by white arrow), ...

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Estrogenic Regulation of the SCF/c-KIT System in Prostate Cells: a Relationship with Prostate Cancer?

Estrogenic Regulation of the SCF/c-KIT System in Prostate Cells: a Relationship with Prostate Cancer?

... o Stem Cell Factor (SCF), são fortes estimuladores da proliferação celular num vasto conjunto de tecidos, e a interacção ligando/receptor parece ter um papel fundamental na ...

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New strategies in hematopoietic stem cell transplantation: G-CSF-mobilized unprocessed whole blood

New strategies in hematopoietic stem cell transplantation: G-CSF-mobilized unprocessed whole blood

... mobilize stem cells but which have not yet been tested in clinical trials include GM-CSF, stem cell factor (8,9), IL-8 (10), IL-3, IL-6, IL-11 (11), and antibodies directed against the ...

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Stem cells – Current concepts and Future applications

Stem cells – Current concepts and Future applications

... hematopoietic stem and progenitor cells (GM- HSPC). The use of stem cells for the treatment of liver disease in both humans and animals has been the focus of considerable ...Mesenchymal stem cells ...

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Stem Cells So far! Stem Cell Therapy Facts and Principles

Stem Cells So far! Stem Cell Therapy Facts and Principles

... cells. Stem cell therapy has now been emerged as an extraordinary promise to treat a wide range of diseases and ...blood stem cell transfer by bone marrow transplant which has been used as an ...

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SDF-1α/CXCR4 Axis Mediates The Migration of Mesenchymal Stem Cells to The Hypoxic-Ischemic Brain Lesion in A Rat Model

SDF-1α/CXCR4 Axis Mediates The Migration of Mesenchymal Stem Cells to The Hypoxic-Ischemic Brain Lesion in A Rat Model

... transcription factor hypoxia-induc- ible factor-1 (HIF-1) is a central regulator that expresses in response to hypoxia which medi- ates systemic homeostatic responses to low levels of oxygen ...

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Therapeutic effects of the transplantation of VEGF overexpressing bone marrow mesenchymal stem cells in the hippocampus of murine model of Alzheimer's disease

Therapeutic effects of the transplantation of VEGF overexpressing bone marrow mesenchymal stem cells in the hippocampus of murine model of Alzheimer's disease

... Mesenchymal stem cells (MSCs), when transplanted into the brain, produce positive effects by reducing amyloid-beta (Aβ) deposition in transgenic amyloid precursor protein (APP)/presenilins1 (PS1) ...growth ...

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Rev. Bras. Hematol. Hemoter.  vol.38 número1

Rev. Bras. Hematol. Hemoter. vol.38 número1

... colony-stimulating factor is the most widely used agent for progenitor cell ...ulating factor generates rapid mobilization of hematopoietic progenitor ...progenitor cell mobilization for ...

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CSPG is a secreted factor that stimulates neural stem cell survival possibly by enhanced EGFR signaling.

CSPG is a secreted factor that stimulates neural stem cell survival possibly by enhanced EGFR signaling.

... differentiated (see Materials and Methods) and scored as follows; tripotent (neurons, astrocytes and oligodendrocytes), bipotent (neurons/astrocytes or oligodendrocytes/astrocytes), unipotent (astrocytes). Data are ...

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Disparate Effects of Mesenchymal Stem Cells in Experimental Autoimmune Encephalomyelitis and Cuprizone-Induced Demyelination.

Disparate Effects of Mesenchymal Stem Cells in Experimental Autoimmune Encephalomyelitis and Cuprizone-Induced Demyelination.

... T cell analysis, mice from 14 days after EAE immunization were killed, perfused with cold Hanks buffered saline solution, and whole brains were ...with cell stimulation cocktail (as described) for 4 hours, ...

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Stem cells labeled with superparamagnetic iron oxide nanoparticles in a preclinical model of cerebral ischemia: a systematic review with meta-analysis

Stem cells labeled with superparamagnetic iron oxide nanoparticles in a preclinical model of cerebral ischemia: a systematic review with meta-analysis

... In addition the positive cells homing reached the injured organ viability by Prussian blue staining, three studies [14,18,26] assessed expressions by using the green fluorescent protein (GFP) and in all cases the sites ...

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The niche-derived glial cell line-derived neurotrophic factor (GDNF) induces migration of mouse spermatogonial stem/progenitor cells.

The niche-derived glial cell line-derived neurotrophic factor (GDNF) induces migration of mouse spermatogonial stem/progenitor cells.

... as cell adhesion, neuronal and fibroblast migration ...at cell-cell contacts, where it has been proposed to promote actin polymerization ...CXCR2-mediated cell migration, indicating the ...

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The role of osteoblasts in regulating hematopoietic stem cell activity and tumor metastasis

The role of osteoblasts in regulating hematopoietic stem cell activity and tumor metastasis

... stromal cell population that facilitates engraftment of marrow stem cells in an allogenic envi- ...stromal cell com- ponent in 5 patients suffering from different life-threatening diseases was ...

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Germline-competent mouse-induced pluripotent stem cell lines generated on human fibroblasts without exogenous leukemia inhibitory factor.

Germline-competent mouse-induced pluripotent stem cell lines generated on human fibroblasts without exogenous leukemia inhibitory factor.

... MEF cells. The first is the ability to reproducibly support deriving iPS cells, which is important for mechanistically dissecting the repro- gramming process. In contrast to MEF cells, HFF cells can proliferate robustly ...

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High expression of hTERT and stemness genes in BORIS/CTCFL positive cells isolated from embryonic cancer cells.

High expression of hTERT and stemness genes in BORIS/CTCFL positive cells isolated from embryonic cancer cells.

... the cell population that expressed BORIS ...NCCIT cell line, classified as germ-cell tumor or embryonic cancer cells ...tumor cell lines, the NCCIT cell line provides a good model for ...

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Nitric oxide from inflammatory origin impairs neural stem cell proliferation by inhibiting epidermal growth factor receptor signaling

Nitric oxide from inflammatory origin impairs neural stem cell proliferation by inhibiting epidermal growth factor receptor signaling

... in cell proliferation were found when compared to untreated ...neurotrophic factor (BDNF), that has been reported to promote neurogenesis (Benraiss et ...

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