Tissue homeostasis
Mutating RBF can enhance its pro-apoptotic activity and uncovers a new role in tissue homeostasis.
... growing tissue promote proliferation of surrounding healthy cells [43], maintaining tissue homeostasis by a process named apoptosis- induced proliferation ...wing tissue overgrowth, we ...
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Macrophages control tissue homeostasis via Ferritin heavy chain
... 4 Although systemic Fe levels are regulated mostly by hepcidin, it is also important to control Fe intracellular levels. This is achieved by the iron regulatory elements/iron regulatory proteins (IRE/IRP) machinery ...
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MOB: pivotal conserved proteins in cytokinesis, cell architecture and tissue homeostasis
... As previously mentioned, different MOB isotypes differentially interact with various Hippo and non-Hippo proteins and can regulate other MOB isotypes. HsMOB1 binds to HsMST1/2, HsNDR1/2, HsLATS1/2, and PRAJA2, acting as ...
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Contribution of the unfolded protein response to breast and prostate tissue homeostasis and its significance to cancer endocrine response
... mammary tissue from virgin, early pregnant and lactating mice lacking XBP-1 disclosed that its deletion correlates to poor branching morphogenesis and impaired terminal end bud formation at the virgin stage, ...
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Critical transition in tissue homeostasis accompanies murine lung senescence.
... In this study, we show that airspace enlargement develops during the mid-range of the murine life-span and progresses through the late, preterminal time points and is accompanied by early oxidative stress, cell death and ...
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Palmitoylation regulates epidermal homeostasis and hair follicle differentiation.
... Palmitoylation is a key post-translational modification mediated by a family of DHHC-containing palmitoyl acyl-transferases (PATs). Unlike other lipid modifications, palmitoylation is reversible and thus often regulates ...
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Liver regeneration and tissue engineering
... In this work, the generation of a novel liver derived biomaterial that could preserve its native vascular network was investigated. We attempted to improve the decellularization of thick tissues and solid organs ...
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Revisiting peri-implant soft tissue - histopathological study of the peri-implant soft tissue
... cial tissue rich in collagen and with scarce cells ...healthy tissue around the implants is very similar, in what concerns the pattern of distri- bution of collagens type I, III, IV, VII and distribu- tion ...
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Tissue-based markers in UTUC
... of tissue- based molecular markers into prognostic tools could help accurately stratify patients for clinical decision-making in this heterogeneous ...on tissue-based markers in UTUC has risen dramatically ...
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Carbonic anhydrase 5 regulates acid-base homeostasis in zebrafish.
... In conclusion, in this study we report the identification of the first vertebrate in vivo model in which defective CA5 activity results in imbalanced cellular acid-base homeostasis. The fact that AZA treatment in ...
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Synaptic Homeostasis and Restructuring across the Sleep-Wake Cycle
... Since both SHY and the synaptic embossing theory have empirical support, computational work may be particularly insightful. SHY has been modeled at the single neuron and network levels, but without real ...
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A study concerning homeostasis and population development of colagen fibers
... Thus, nowadays it is believed that bimodality of fiber diameters leads to a compro- mise between resistance and resilience of the tissue [37], although the details are far from being completely clarified. First, ...
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Local iron homeostasis in the breast ductal carcinoma microenvironment
... With the present cross-sectional approach it was not possible to establish a real timeline for breast cancer de- velopment and progression. Moreover, the fact that this is an anonymous cross-sectional study without ...
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Volatile emissions from compressed tissue.
... Since almost every fifth patient treated in hospital care develops pressure ulcers, early identification of risk is important. A non-invasive method for the elucidation of endogenous biomarkers related to pressure ulcers ...
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Liquid Crystalline Microenvironments For Tissue Engineering
... of tissue engineering, hydrogels and silicon elastomers with LC properties were applied to the study of cell ...connective tissue, representing an enormous breakthrough in tissue regeneration and in ...
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Multimodal phantom of liver tissue.
... The liver model has been positively evaluated by four expert surgeons who have done a high number of liver resection, both open and laparoscopically, radiologists, and engineers who work on medical imaging. Comparison of ...
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Cell-based bone tissue engineering.
... Nevertheless, the quality of allografts is worse than that of autologous grafts. Allografts have a poor degree of cellularity, less revascularisation, and a higher resorption rate compared to autologous grafts [3,6], ...
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Gene Technology in Tissue Engineering
... of tissue injury to accelerate and/or induce a natural biological regeneration, gene technology has been developed in tissue engineering for many tissues and organs such as bone [4, 15, 19] , cartilage ...
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Advances in Retinal Tissue Engineering
... localized tissue grafts. Subsequently, retinal tissue engineers have drawn upon the success of bone, cartilage and vasculature tissue engineering by employing a polymeric tissue engineering ...
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Reelin secreted by GABAergic neurons regulates glutamate receptor homeostasis.
... Brefeldin A is a non-selective inhibitor of protein secretion. To demonstrate that the lack of reelin secretion caused the increase in the fraction of NR2B-containing NMDARs, we performed rescue experiments. We examined ...
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