Transcription factor
The role of the transcription factor SIM2 in prostate cancer.
... the transcription factor SIM2 is still poorly ...bHLH/PAS transcription factor single minded 2s was reported to promote mammary gland lactogenic differentiation by regulation of Csn2 ...
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Comprehensive human transcription factor binding site map for combinatory binding motifs discovery.
... between transcription factors (TFs) and their binding sites is essential to reverse engineer the regulation ...the transcription factor binding motifs (TFBMs) have been ...
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Association of transcription factor gene LMX1B with autism.
... In this study, we examined the association of the transcription factor gene LMX1B with autism in Caucasian population. In the trio-based study, we found nominal associations for two SNPs (rs10732392 and ...
7
Phenotypic robustness and the assortativity signature of human transcription factor networks.
... a transcription factor [41] and the regulatory interactions included in the TFN ...the transcription start site), the assortativity signature of the TFN is qualitatively similar to that observed ...
12
A linear model for transcription factor binding affinity prediction in protein binding microarrays.
... We present a new linear motif model that represents a TF’s binding affinity toward a DNA sequence as a linear combination of its affinities towards the variable-length K-mers that make up the DNA sequence. Here by ...
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A structural-based strategy for recognition of transcription factor binding sites.
... potential transcription factor binding sites (TFBSs) is becoming increasingly important in this post-genomic ...many transcription factor (TF) motifs are short and highly degenerate, and ...
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Transcription factor binding sites prediction based on modified nucleosomes.
... for transcription factor binding site (TFBS) ...to transcription start sites to distinguish true binding regions from random ...with transcription factor binding ...using ...
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Role of the Cyclosporin-sensitive Transcription Factor NFAT1 in the Allergic Response
... of transcription factors that dictate expres- sion of different cytokines (Crabtree 1989, Paul & Seder ...NFAT1 transcription factor in the in vivo immune response, two different groups generated ...
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Utrophin up-regulation by an artificial transcription factor in transgenic mice.
... synthetic transcription factor introduced in vivo is well tolerated and safe for the health of the transgenic animal both during development and in adult life; ii) Vp16-Jazz was able to recognize ...
8
The transcription factor REST is lost in aggressive breast cancer.
... silencing transcription factor (REST) is lost in colon and small cell lung cancers and is known to induce anchorage-independent growth in human mammary epithelial ...
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DNA-MATRIX: a tool for constructing transcription factor binding sites Weight matrix
... For testing, we used the known PurR transcription factor binding sites, to construct the weight matrix similar to earlier reported. We found 92% accuracy with aligned motifs of same width. Most of the ...
3
Prediction of nucleosome positioning based on transcription factor binding sites.
... Principal Findings: Here, the minimum redundancy maximum relevance (mRMR) feature selection algorithm, the nearest neighbor algorithm (NNA), and the incremental feature selection (IFS) method were used to identify the ...
7
Structure-function relationships of the Mycobacterium tuberculosis transcription factor WhiB1.
... M. tuberculosis is the causative agent of tuberculosis (TB) and is a major worldwide healthcare problem [1]. As is the case for many bacterial pathogens, the ability of M. tuberculosis to cause disease requires efficient ...
5
Analysis of the stress-inducible transcription factor SsNAC23 in sugarcane plants
... rice transcription factor OsNAC6 was ...plant-specific transcription factors, with important roles in development, growth and response to stress (Kikuchi et ...
8
The DAF-16/FOXO transcription factor functions as a regulator of epidermal innate immunity.
... growth factor signaling, by LY294002 (a specific inhibitor of PI3K), strongly accelerates scratch closure in human keratinocytes ...growth factor pathway leads to the activation of FOXO transcription ...
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Generation of a Conditional Allele of the Transcription Factor Atonal Homolog 8 (Atoh8).
... differentiation transcription factors Neurog3, Pax4, NeuroD1 and ...genetic factor shown to specify δ-cell fate during pancreatic development ...this transcription factor, at least at this ...
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Wild type p53 transcriptionally represses the SALL2 transcription factor under genotoxic stress.
... growth factor- (TGF ) in Drosophila, acts as an upstream regulator of spalt ...Growth Factor (NGF) was shown to positively regulate SALL2 in rat neurons ...(AP4) transcription factor ...
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Helicase-like transcription factor (Hltf) regulates G2/M transition, Wt1/Gata4/Hif-1a cardiac transcription networks, and collagen biogenesis.
... helicase-like transcription factor (Hltf) null mouse model indicates Hltf has an important role in cardiac morphogenesis through its regulation of Gata4 and ...
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Simplified method for predicting a functional class of proteins in transcription factor complexes.
... replication, transcription, and translation [1]. Initiation of transcription is in the core of most of the cellular responses to environmental conditions ...within transcription factor (TF) ...
5
Transcription factor SP4 is a susceptibility gene for bipolar disorder.
... The Sp4 transcription factor plays a critical role for both development and function of mouse hippocampus. Reduced expression of the mouse Sp4 gene results in a variety of behavioral abnormalities relevant ...
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