[PDF] Top 20 Alterations of the TP53 Gene in Gastric and Esophageal Carcinogenesis
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Alterations of the TP53 Gene in Gastric and Esophageal Carcinogenesis
... therapy, the Pro/Pro genotype was associated with shorter overall survival and progression, independent of standard clinical prognostic features, thus the authors suggest that TP53 ... See full document
14
MYC, TP53, and Chromosome 17 Copy-Number Alterations in Multiple Gastric Cancer Cell Lines and in Their Parental Primary Tumors
... composed of a heterogeneous clonal population which can include nonneoplastic ...cells. The increased frequency of cells with MYC gain, TP53 loss, and chr17 trisomy in cell lines ... See full document
9
Widespread hypomethylation occurs early and synergizes with gene amplification during esophageal carcinogenesis.
... profiling: the HELP assay The HELP assay was performed as published previously[23,24], in summary, genomic DNA was isolated from cell lysates ...8.0 and 1% SDS), digested overnight at 50C on ... See full document
14
hTERT, MYC and TP53 deregulation in gastric preneoplastic lesions
... increase of MYC mRNA expression during the sequential steps of gastric carcinogenesis in MNU-treated animals ...[24]. In these animals, the mRNA expression ... See full document
8
MYC, FBXW7 and TP53 copy number variation and expression in Gastric Cancer
... [20] and Leder et ...promote the development of cancer in transgenic mouse models. The increase in MYC mRNA level in human cancers may result from both direct and ... See full document
10
Methylation status of ANAPC1, CDKN2A and TP53 promoter genes in individuals with gastric cancer
... is the forth most frequent malignancy and the second most common cause of cancer death ...is the most studied epigenetic alteration, occurring through a methyl radical addition to ... See full document
5
J. Bras. Patol. Med. Lab. vol.38 número3
... efficiency of the chemical carcinogenesis protocol used (DMBDD) was demonstrated by the increased frequency of preneoplastic lesions and benign neoplasia in the ... See full document
8
Gene amplification in carcinogenesis
... Amplification of the CCND1 oncogene also occurs in the early stages of these tumors and persists during the ad- vanced stages of the disease, although ... See full document
7
Interrelationship between TP53 gene deletion, protein expression and chromosome 17 aneusomy in gastric adenocarcinoma
... Fluorescence in situ hybridization (FISH) assay allows rapid detection of numerical genetics aberrations in inter- phase nuclei in tumor ...heterogeneity in gene or loci copy ... See full document
7
Detection of microsatellite instability but not truncating APC mutations in gastric adenocarcinomas in Brazilian patients
... for the adenomatous polyposis colonic (APC) gene in colorectal carcinogenesis has been conclusively established, but, the role of APC in gastric tumors remains ... See full document
6
Contractile profile of esophageal and gastric fundus strips in experimental doxorubicin-induced esophageal atresia
... model and detected reductions in the density and distribution of the myoenteric plexus, specifically regard- ing vasoactive intestinal peptide- (VIP-) and substance ... See full document
7
Genetic screening analysis of patients with hereditary diffuse gastric cancer from northern and northeastern Brazil
... is the first study to evaluate CDH1 gene germline mutations and quantitative gene alterations in Brazilian families with ...CDH1 gene germline mutations were found ... See full document
8
The modification process of AlSi21CuNi silumin and its effect on change of mechanical properties of the alloy
... operations and with segregation of crystals of primary silicon, hypereutectic silumins can be used after modification ...elaboration of effective modification methods is necessary for complete ... See full document
4
The TP53 Gene, its Products and Regulation
... suppressor, and the existence of p53-like proteins in short-lived organisms that do not exhibit adult cancer incidence, such as flies and worms, adds to the argu- ment that tumor ... See full document
8
in Esophageal Cancer Associated with Synchronous Gastric
... In the postoperative the patient showed acute respiratory dysfunction syndrome and was admitted at Intensive Care Unit for a period of ten ...5a and 5b). After his stay at ... See full document
1
Rev. Assoc. Med. Bras. vol.59 número6 en v59n6a04
... seen in daily medical care is that the gastric band has poor results in weight loss and high complication ...inhibited the indication of gastric bands worldwide, ... See full document
2
Strategies and Problems in the Promotion of Taal as a Culture and Religious Destination
... projects and for religious conventions and ...number of people who seek spiritual aspects to their ...industry in Taal and Maragondon contributes to the local community by ... See full document
5
Int. braz j urol. vol.37 número3
... combination of these proteins may be of clinical use as in other tumors ...signaling and has been found to suppress prostate carcinogenesis in TRAMP mice ...expression in ... See full document
5
Determinants and Consequences of the Website Perceived Value
... emerge in the 1990s as an issue of growing interest to business, in particular to marketing at both academic and practitioner ...one of the most significant factors ... See full document
13
Arq. Gastroenterol. vol.45 número3
... studied in the supine position after 12 h of fasting. The catheter was introduced through the ...For the study of esophageal contractions, the catheter was ... See full document
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