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[PDF] Top 20 Alternative splicing and SR proteins in ABA-mediated stress responses

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Alternative splicing and SR proteins in ABA-mediated stress responses

Alternative splicing and SR proteins in ABA-mediated stress responses

... for SR proteins as central coordinators of plant abiotic stress responses, namely by targeting ABA pathway ...RS40 and RS41, two members of the plant-specific RS subfamily are ... See full document

49

Functional and molecular characterization of SR45, a plant-specific splicing factor involved in sugar and stress signaling in Arabidopsis thaliana

Functional and molecular characterization of SR45, a plant-specific splicing factor involved in sugar and stress signaling in Arabidopsis thaliana

... the splicing machinery. Two studies by Green and co- workers have shown that the RS domain can also directly contact with the branch point site and the 5’ splice site to promote splicing (Shen ... See full document

238

Transportin-SR is required for proper splicing of resistance genes and plant immunity.

Transportin-SR is required for proper splicing of resistance genes and plant immunity.

... role in RNA splicing, we analyzed splicing of two housekeeping genes Actin1 and b-tubulin4 by RT-PCR using primers that flank ...that splicing of Actin1 and b-tubulin4 was not ... See full document

10

Small-molecule inhibition of HIV pre-mRNA splicing as a novel antiretroviral therapy to overcome drug resistance.

Small-molecule inhibition of HIV pre-mRNA splicing as a novel antiretroviral therapy to overcome drug resistance.

... of SR proteins and thereby impede its phosphorylation, at least in vitro, by SR kinases ...both splicing activity and subcellular trafficking of SR proteins ... See full document

10

Eye development under the control of SRp55/B52-mediated alternative splicing of eyeless.

Eye development under the control of SRp55/B52-mediated alternative splicing of eyeless.

... influences alternative splicing of eyeless pre-mRNA is still unknown. In vitro data showed that B52 binds directly the alternative exon 2 and mediates its ...binding proteins ... See full document

10

Protection against retrovirus pathogenesis by SR protein inhibitors.

Protection against retrovirus pathogenesis by SR protein inhibitors.

... simple splicing substrates [12], these molecules reveal to inhibit splicing events in vivo with good ...production in cells chronically infected by the virus. Since HIV-1 alternative ... See full document

8

Laboratory of Plant Molecular Biology

Laboratory of Plant Molecular Biology

... Alternative splicing, which by selectively joining different splice sites generates multiple transcripts from the same precursor mRNA (pre-mRNA), provides a key posttranscriptional regulatory mechanism for ... See full document

265

Proteasome-mediated proteolysis of SRSF5 splicing factor intriguingly co-occurs with SRSF5 mRNA upregulation during late erythroid differentiation.

Proteasome-mediated proteolysis of SRSF5 splicing factor intriguingly co-occurs with SRSF5 mRNA upregulation during late erythroid differentiation.

... SR proteins exhibit diverse functions ranging from their role in constitutive and alternative splicing, to virtually all aspects of mRNA ...interest in deciphering the ... See full document

17

Strategies for identifying RNA splicing regulatory motifs and predicting alternative splicing events.

Strategies for identifying RNA splicing regulatory motifs and predicting alternative splicing events.

... tested in various standard splicing contexts, ESE and ESS elements are currently the best characterized ...(SR) proteins, which themselves recruit other spliceosomal components via ... See full document

10

Identification of a novel function of CX-4945 as a splicing regulator.

Identification of a novel function of CX-4945 as a splicing regulator.

... Alternative splicing is a nearly ubiquitous versatile process that controls gene expression and creates numerous protein isoforms with different functions from a single ...of alternative ... See full document

8

Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics.

Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics.

... SMARCA4 and SMARCA5) are shown to be differentially expressed in diverse cancer cell ...interaction in the context of CS symptoms remains to be ...SMARCA4 and SMARCA5 ...observed in CSB ... See full document

17

Alternative splicing detection across different tissues in cork oak

Alternative splicing detection across different tissues in cork oak

... step in RNA-seq ...reads and correctly determining exon-intron junctions, taking into account the variable size gaps generated by ...BWA and Bowtie) designed for DNA alignment tend to fail (Baruzzo ... See full document

75

A Computational Platform for Assessing the Impact of Alternative Splicing in Cancer

A Computational Platform for Assessing the Impact of Alternative Splicing in Cancer

... common in molecular biology to have tasks that are frequently done and are composed by a set of steps (a ...necessary, and the pipeline would be stored as a single software tool. Some steps in ... See full document

82

Alternative promoters influence alternative splicing at the genomic level.

Alternative promoters influence alternative splicing at the genomic level.

... comparison. In all three examples of full-length cDNA comparisons, constitutive exons are shown in gray, alternatively spliced exons are shown in red, and introns are represented by solid ... See full document

8

An EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype.

An EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype.

... EMT, alternative splicing of several genes has also been correlated with EMT progression, but the extent of splicing changes and their contributions to the morphological conversion ... See full document

21

A pan-cancer analysis of transcriptome changes associated with somatic mutations in U2AF1 reveals commonly altered splicing events.

A pan-cancer analysis of transcriptome changes associated with somatic mutations in U2AF1 reveals commonly altered splicing events.

... 2 and Table 1, Fisher’s exact test p ,2.2e-16). For all 30 splicing events, the direction of splicing was the same in both cancer types, where U2AF1 mutation caused a shift to exon skipping or ... See full document

10

Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome.

Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome.

... MeCP2-interacting proteins in the brain, we created a knockin mouse line (Mecp2-Flag) that expresses Flag-tagged MeCP2 from the endogenous Mecp2 ...antibody in the ...because in the past, ... See full document

25

Overexpression of EcbHLH57 Transcription Factor from Eleusine coracana L. in Tobacco Confers Tolerance to Salt, Oxidative and Drought Stress.

Overexpression of EcbHLH57 Transcription Factor from Eleusine coracana L. in Tobacco Confers Tolerance to Salt, Oxidative and Drought Stress.

... variation in the threshold levels of ...the stress responsive functional or regulatory gene transcripts/pro- teins from tolerant species are either stable or functionally more efficient under stress ... See full document

21

Fine-scale variation and genetic determinants of alternative splicing across individuals.

Fine-scale variation and genetic determinants of alternative splicing across individuals.

... of alternative pre–mRNA splicing (AS) in the human ...complexity in isoform-level expression differences between ...published splicing sensitive microarray data from lymphoblastoid cell ... See full document

13

The friction influence on stress in micro extrusion

The friction influence on stress in micro extrusion

... The wave model reveals increase of friction shear factor m values at the interface in micro scale. Its presence affects the level of extrusion forces. The higher wave height while the same process, requires the ... See full document

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