[PDF] Top 20 Analysis of time to event outcomes in randomized controlled trials by generalized additive models.

... obtained by averaging over the covariate distribution of the HEMO study participants is nearly identical to an unconditional PGAM ...found in the seminal paper by Gail et al[88] which ... See full document

... meta-analysis by adopting fixed- and random-effects models to compare B vitamin supplementation versus placebo for the outcomes stroke, cerebral infarc- tion and cerebral ...According ... See full document

... [34] of stroke prevention that was published in 2007, which suggested that folic acid supplementation can effectively reduce the risk of stroke in primary ...prevention. In a cumulative ... See full document

... no event of interest in a treatment group, 1.0 was added to all cells for continuity correction ...scale of 0% to 100% ...Subgroup analysis was performed to test ... See full document

... data analysis. Two investigators (YNW and SLA) were involved in the statistical ...Measurement of outcomes was considered in terms of original data at each follow-up time ... See full document

... All randomized controlled trials (RCTs) of therapies re- lated to symptoms associated with primary or intrinsic ...and analysis: Two reviewers extracted data from the in- ... See full document

... used to estimate the results of the dichotomous data, including ISR and clinical outcomes (TVR, TLR, MI, stent thrombosis, and ...calculated to evaluate continuous data obtained from QCA ... See full document

... conducted in the PubMed, Cochrane Library, Lilacs (Literatura Latino-Americana e do Caribe em Ciências da Saúde), SciELO (Scientific Electronic Library Online) and Embase ...Only randomized ... See full document

... Institute of Diabetes and Digestive and Kidney Diseases, the Canadian Diabetes Association, the Canadian Nutrition Society, the Calorie Control Council, the Diabetes and Nutrition Study Group of the ... See full document

... references, of which 339 articles were excluded during the first screening, which was based on abstracts or titles, leaving 12 articles for full text ...non- randomized trial (n=6); both groups treated ... See full document

... limitations of this study are the inclusion of trials of low methodological and surgical quality and the presence of significant heterogeneity in the ...reviews of RCTs ... See full document

... included trials [10,11,12,13,14,15], sequence generation which means a low risk of bias was clearly conducted and introduced in five studies ...method of randomization in spite ... See full document

... tools to verify the quality assessment of randomized and non-randomized ...objective to help the researchers to rapidly identify if these studies contain enough internal and ... See full document

... pylori in both in vitro and in vivo models. To systematically evaluate whether moxifloxacin-containing triple therapy could improve eradication rates and reduce side effects in ... See full document

... concentrations where the majority of the data exist. The higher values for the smooth result mainly from late morning and early afternoon observations on a single day when OH radical concentrations were ... See full document

... Register of Controlled Trials (CENTRAL, - present) without language ...Stroke Trials Registry, International Clinical Trials Registry Platform (ICTRP) and International Standard ... See full document

... differences in trial characteristics between RCTs designed for elderly and not specifically designed for ...respect to the amount of participants, in comparison to trials not ... See full document

... role of GnRHa in the protection of chemotherapy-induced gonadal ...loss in patients of different ages, but the clinical application is limited to young women with good ovarian ... See full document

... sedation in cirrhotic patients because propofol exhibits greater suppressive cardiopulmonary effects than midazolam ...agents to sedate patients undergoing GIE with sedation using propofol alone, and ... See full document

... most of the published studies address symptom relief in the ...aimed to perform a systematic review and meta-analysis focused on evaluating the efficacy of the different endoscopic ... See full document