[PDF] Top 20 Antigenicity and Immunogenicity of Plasmodium vivax Merozoite Surface Protein-3
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Antigenicity and Immunogenicity of Plasmodium vivax Merozoite Surface Protein-3
... utility of merozoite surface protein (MSP)-3 as a vaccine against Plasmodium falciparum ...use of Plasmodium vivax MSP-3 (PvMSP-3) as a target ... See full document
10
Serological detection of Plasmodium vivax malaria using recombinant proteins corresponding to the 19-kDa C-terminal region of the merozoite surface protein-1
... samples of P. vivax infected individuals, we observed that values obtained for the recombinant proteins His 6 -MSP1 19 and His 6 -MSP1 19 -PADRE were significantly higher than those obtained for ... See full document
7
Seleção e desenvolvimento de adjuvantes para uso em imunizações com proteínas recombinantes de Plasmodium
... acids of the C-terminal domain of the Plasmodium vivax merozoite surface protein-1 and the hexa-histidine tag (His 6 MSP1 19 ...One of these recombinant ... See full document
191
Ricardo de Godoi Mattos Ferreira2 , Luiz Hildebrando Pereira-da-Silva
... interventions and a potential vaccine ...sequences of the Plasmodium falciparum antigen PfCLAG9 were found in sera of falciparum malaria patients from Rondônia, in the Brazilian ...semi-immune ... See full document
8
Analysis of the genetic variability of PvMSP-3 α among Plasmodium vivax in Brazilian field isolates
... understanding of the molecular epidemiology of Plasmodium vivax, which is a neglected human malaria ...aim of this study was to analyze the genetic diversity of P. vivax ... See full document
8
The Duffy binding protein as a key target for a Plasmodium vivax vaccine: lessons from the Brazilian Amazon
... P. vivax Duffy binding protein (PvDBP) as a blood-stage vaccine candidate - The inva- sion of red blood cells (RBCs) by Plasmodium merozo- ites - an essential event in the life cycle of ... See full document
10
Conformational dynamics and antigenicity in the disordered malaria antigen merozoite surface protein 2.
... consistency of the antigenic profiles we have measured here between animals and with other previous studies in mice and in humans, strongly suggests that these profiles are deter- mined by the ... See full document
18
BM5 - SEQUENCE DIVERSITY, ANTIBODY RECOGNITION AND EVOLUTION OF THE MALARIA VACCINE CANDIDATE ANTIGEN MEROZOITE SURFACE PROTEIN-2 (MSP-2) OF PLASMODIUM FALCIPARUM
... T. vivax during the last decades, consequently very few markers have been described for its molecular ...T. vivax confronted with nearly 98319, 38686, 23586 for ...cruzi and Leishmania, respectively. ... See full document
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Plasmodium vivax antigen discovery based on alpha-helical coiled coil protein motif.
... functions of medically important microorganisms, represent a means for vaccine ...total of 50 antigens with a-helical coiled coil motifs orthologous to Plasmodium falciparum were identified in the ... See full document
13
Érika Martins Braga, Melissa da Silva Bastos, Gerhard Wunderlich, José Rodrigues Coura
... patterns of malaria transmission, we measured naturally acquired IgG antibodies to the con- served 19-kDa C-terminal region of the merozoite surface protein (MSP)-1 of both ... See full document
10
Immunogenicity of a Prime-Boost Vaccine Containing the Circumsporozoite Proteins of Plasmodium vivax in Rodents
... animals and more recently with humans provide a solid basis for the use of vaccines against CSP to prevent ...deadly Plasmodium falciparum parasite tested in a phase III clini- cal trial is RTS,S, a ... See full document
15
Expression and Evaluation of Recombinant Plasmodium knowlesi Merozoite Surface Protein-3 (MSP-3) for Detection of Human Malaria.
... extraction and construction of recombinant expression plasmid Plasmodium knowlesi DNA was extracted from patient blood sample using a commercial blood extraction kit (Qiagen, Hilden, ...set of ... See full document
15
A Library of Plasmodium vivax Recombinant Merozoite Proteins Reveals New Vaccine Candidates and Protein-Protein Interactions.
... studies of P. vivax generally lag behind those of ...lack of a robust in vitro culture system, which complicates investigation of ...P. vivax erythrocyte invasion and thus ... See full document
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Differing patterns of selection and geospatial genetic diversity within two leading Plasmodium vivax candidate vaccine antigens.
... evidence of geographic clustering. This juxtaposition between pvmsp-1 and pvcsp sequences is similar to what has previously been described for merozoite and sporozoite antigens in ...P. ... See full document
17
Chemoresistance of Plasmodium falciparum and Plasmodium vivax parasites in Brazil: consequences on disease morbidity and control
... number of SNPs were identified in critical codons of the pfdhfr (pyrimethamine) and pfdhps (sulphadoxine) genes, and these were related to acquisition of full SPR (Cowman et ...case ... See full document
8
Cells and mediators of inflammation (C-reactive protein, nitric oxide, platelets and neutrophils) in the acute and convalescent phases of uncomplicated Plasmodium vivax and Plasmodium falciparum infection
... changes and release of soluble mediators, particularly C-reactive protein (CRP) and nitric oxide (NO), during uncomplicated malaria have not been well studied, especially in Brazilian areas in ... See full document
7
Sequence polymorphisms in Pvs4845 and Pvs47 gametocyte and gamete surface proteins in Plasmodium vivax isolated in Korea
... number of patients with malaria decreased to 841 in ...Kimpo and Pajoo, which are high-risk malaria areas, located in the north- west region of the ROK near the ...P. vivax infection presents ... See full document
9
CLINICAL AND LABORATORY FINDINGS OF Plasmodium vivax MALARIA IN COLOMBIA, 2001
... Se realizó un estudio descriptivo con 104 enfermos de malaria por Plasmodium vivax, en Turbo (Antioquia, Colombia). Se evaluaron las características clínicas y los niveles de hemoglobina, glicemia, ... See full document
6
Severe malaria and Plasmodium
... matrix, and was first identi- fied as a receptor for parasite binding to Saimiri monkey endothelial brain cells and to Chinese hamster ovary cells ...sequestration of CSA-bind- ing parasites in the ... See full document
12
Plasmodium vivax Transmission in Africa.
... observations of Pv in Africa are not mutually ...diversity of transmission, it seems probable that all are involved to some ...source of infection would vary between location: in remote forest areas, ... See full document
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