[PDF] Top 20 The association between three cyclooxygenase-2 polymorphisms and hepatocellular carcinoma risk: a meta-analysis.

... The cyclooxygenase-2 (COX-2) is one of the key enzymes of prostaglandin pathway, since it can convert the arachidonic acid to ...regulation and apoptosis inhibition, as a ... See full document

... stratification analysis by ethnicity and cancer types. The results indicated that variant genotypes of TLR2 2196 to 2174 del tended to be associated with overall cancer risk in Caucasians ... See full document

... genetic association studies have assessed the relation of the IL1B (-511) and (+3954), and IL1RN (VNTR) polymorphisms with GD risk; however, the findings remain ... See full document

... frequencies between HCC patients and healthy controls (Table ...Regarding the c.335T.C variants, the CC genotype was strongly associated with an increased risk of developing HCC ... See full document

... shown between the Fok1 polymorphism and Bsm1, Taq1 and Apa1 polymorphisms ...within the VDR gene. The effect of this SNP on breast cancer is plausible, given that ... See full document

... Indian and Chinese. Using meta-analysis, we found that carrying H allele of D19H polymorphism was associated with an increased risk of gallstone ...polymorphism and carrying K allele of ... See full document

... currently the most common cancer and one of the main causes of cancer-related death in the world, which has become a major public health challenge ...genetic and environmental factors ... See full document

... science and the CNKI databases were systematically searched to identify relevant ...(ORs) and 95% confidence intervals (95% CIs) were used to assess the strength of ...subgroup analysis ... See full document

... Embase, and Cochrane library databases up to October 01, 2013 using the following search strategy: (‘‘colorectal cancer’’, ‘‘CRC’’, ‘‘colon cancer’’ or ‘‘rectum cancer’’) and ... See full document

... pooled association studies. Although the overall association of HHEX gene with type 2 diabetes reached significance, there was moderate to strong evidence of heterogeneity attributable to ... See full document

... that the rs10830963 polymorphism of MTNR1B is a risk factor for developing type 2 ...In the stratified analysis by ethnicity, significant associations were found in Caucasians for ... See full document

... measure the relationship between COX-2 immunoexpression and clinical ...on the predictive ability of COX-2 for 24-month clinical outcomes were combined across studies in a ... See full document

... established risk factor, such as smoking habits, was not recorded and systematically stratiied according for genotypes in most of the ...comprehensive analysis. Only three studies ... See full document

... model and allelic models was also done to estimate cancer ...when the P was ,0.05. In case of a significant heterogeneity, the pooled ORs were analyzed using a random effects model (the ... See full document

... databases and included several additional studies, which allowed for a larger number of subjects (17 studies including 4198 cases and 4194 controls) and more precise risk ...stratified ... See full document

... of the association between MTHFR (C677T and A1298C) polymorphisms and AML risk was measured by using crude odds ratio (OR) with 95% confidence interval ...(CI). The ... See full document

... Asians and Caucasians for the 2 exon 7 genotype variants, however no significant association was found in mixed ...that polymorphisms of CYP1A1 exon 7 polymorphism may be important in ... See full document

... with risk of T2DM. However, no association of the IL-10 2592C/A or 2819C/T polymorphism with T2DM risk was ...heterogeneity between studies in our analyses. We then assessed the ... See full document

... investigated the relationship between VEGF receptor gene poly- morphisms and stroke, but they failed to reach the same ...This meta-analysis was performed to identify the ... See full document

... erection and is implicated in erectile ...used the rabbit CC, organization of its components is not well known to ...characterized and quantified the volumetric density (Vv) of the ... See full document