[PDF] Top 20 Association of TLR2 and TLR4 polymorphisms with risk of cancer: a meta-analysis.

... term of stratified analyses by races, our findings indicated that TLR2 2196 to 2174 del had an significant association with cancer risk in Caucasians and South Asians, but ... See full document

... present meta-analysis has some advantages compared to the previous ...English and Chinese language in this meta-analysis; therefore, publication bias may have ...this ... See full document

... distribution of Hardy-Winberg equilibrium (HWE) in controls, chi-square test for goodness of fit was conducted and a ...disequilibrium of HWE. We assessed the association strength ... See full document

... the association between PTGS1 or PTGS2 polymorphisms and NSAID use on the risk of developing ...region of PTGS1 are known, 1 polymorphism (rs3842787) was analyzed by 3 ... See full document

... results of the current meta-analysis, some limitations need to be ...small and may not provide sufficient power to estimate the association between ESR1 gene polymorphisms ... See full document

... functional analysis in vitro showed that the 5A allele had approximately 2-fold higher promoter activity than the 6A ...levels and contributes to the carcinogenesis of most ...the association ... See full document

... significant association was observed between MTHFR C677T polymorphism and susceptibility to ovarian cancer ...significant association between MTHFR A1298C polymorphism head and neck ... See full document

... search of all English reports on studies for the association between the TP53BP1 Asp353Glu (rs560191) polymorphism and susceptibility to cancer using Medline, the Cochrane Library, EMbase, Web ... See full document

... one of the key enzymes of prostaglandin pathway, since it can convert the arachidonic acid to ...regulation and apoptosis inhibition, as a risk factor in carcinogenesis of HCC [4, ... See full document

... total of 74 relevant publications after initial ...criteria and were subjected to further ...data with those included in the analysis ...consisted of 44 publications [69–112] ... See full document

... importance of the SNPs in TLR4 (Asp299Gly) and TLR9 (-1237C/T and -1486C/T) in ...This meta-analysis study suggests the implications of these TLR polymorphisms on ... See full document

... significant association was found between it and schizophrenia risk in Asian and Caucasian populations under allelic, dominant and recessive ...Sensitivity analysis revealed that ... See full document

... this association. The first is via activation of insulin and the IGF pathway which share affinity with insulin and important to cell proliferation and apoptosis ...associated ... See full document

... Qin and Qiliu Peng) independently reviewed and extracted data from all eligible ...year of publication, country of origin, ethnicity, genotyping method, matching criteria, source of ... See full document

... mediators of the inlammatory response to malarial infection, and gene polymorphisms affecting TLR function may be partially responsible for inter-individual variation in disease ...associations ... See full document

... (rs4553808) polymorphisms and cancer susceptibility. Third, the lack of detailed original data, such as the age and sex of the populations, smoking status, or alcohol consumption ... See full document

... Embase, and Cochrane library databases up to October 01, 2013 using the following search strategy: (‘‘colorectal cancer’’, ‘‘CRC’’, ‘‘colon cancer’’ or ‘‘rectum cancer’’) and ... See full document

... test and I 2 ...lack of heterogeneity among studies, the pooled OR estimate of the each study was calculated by the fixed-effects model (the Mantel–Haenszel method) ...DerSimonian and Laird ... See full document

... this meta-analysis, we find that GG genotype of mir-146a may be a protective factor for OS, especially in Asian ...significant association with recurrence and DFS was detected in ... See full document

... extracted and tabulat- ed all the relevant data ...complete and newly released study was ...name of the first author, publication year, ethnic origin of the studied population, numbers ... See full document