[PDF] Top 20 Chloroquine is therapeutic in murine experimental model of paracoccidioidomycosis
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Chloroquine is therapeutic in murine experimental model of paracoccidioidomycosis
... pH, chloroquine interferes with intracellular iron metabolism in at least two major ...release of iron from HTF endocytized via transferrin receptors ...it is endocytized, and the endocytic ... See full document
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Anti-inflammatory effects of rebamipide eyedrop administration on ocular lesions in a murine model of primary Sjogren's syndrome.
... [6,7,18,19]. In a previous report, we demonstrated that the oral administration of Reb had a therapeutic effect on autoimmune lesions of the salivary glands in thymectomized NFS/sld ... See full document
7
Dermatophyte-host relationship of a murine model of experimental invasive dermatophytosis
... employed model animals in studies of derma- tophytosis ...One of them is that these experimental models have not been used to explore the mechanisms involved in immune ... See full document
8
Excisional wound healing is delayed in a murine model of chronic kidney disease.
... The model we have presented possesses several advantages for the study of CKD-impaired wound healing in ...vivo. In particular, the model’s technical ease, along with a lack of local ... See full document
10
The role of adjuvants in therapeutic protection against paracoccidioidomycosis after immunization with the P10 peptide
... days of infection, immunizations were initiated with three weekly doses of P10 with or without the different ...days of infection, the fungal load was evaluated by enumeration of CFUs from ... See full document
6
The left lung is preferentially targeted during experimental paracoccidioidomycosis in C57BL6 mice
... phase of a systemic experimental model of PCM, we infected C57BL/6 mice with Pb18 yeast cells and evaluated the fungal recovery at day 70 ...shown in Figure 1C, the numbers of ... See full document
5
Therapeutic effects of human amniotic fluid-derived stem cells on renal interstitial fibrosis in a murine model of unilateral ureteral obstruction.
... Oct-4 is a marker of pluripotent stem ...analyses of cellular Figure ...analysis of Collagen I ...staining of Collagen I was seen in renal ...expression of Collagen I ... See full document
14
Iron labeling and pre-clinical MRI visualization of therapeutic human neural stem cells in a murine glioma model.
... efficacy of this treatment largely depends on the ability of the stem cells to adequately target and distribute throughout tumor ...maximize therapeutic benefit, optimal timing of treatment ... See full document
12
Nitric oxide releasing nanoparticles are therapeutic for Staphylococcus aureus abscesses in a murine model of infection.
... benefit of NO-np treatment of MRSA abscesses is the stimulation of healing by induction of collagen ...Acceleration of wound healing by nitric oxide donors has been demonstrated ... See full document
7
Therapeutic effects of the transplantation of VEGF overexpressing bone marrow mesenchymal stem cells in the hippocampus of murine model of Alzheimer's disease
... role of microglia in AD that has been recently accepted is the clearance of the Aβ protein by phagocytosis (Simard et ...effects of microglial activation in removing β-amyloid ... See full document
15
Phage therapy is effective against infection by Mycobacterium ulcerans in a murine footpad model.
... this is the first study on mycobacteriophage therapy against M. ulcerans in vivo ...stage of M. ulcerans infection, which is relevant for human infection since BU patients often seek medical ... See full document
10
Chromoblastomycosis Murine Model and In vitro Test to Evaluate the Sensitivity of Fonsecaea pedrosoi to Ketoconazole, Itraconazole and Saperconazole
... cure-rate of 37% was obtained with KTZ; this cure-rate data is closer to that found in clinical studies, which have rendered a 41 to 50% cure- rate (Drouhet et ...The in vitro findings and the ... See full document
6
Cytokine production in experimental paracoccidioidomycosis of murine selected lineages for acute inflammatory response (air)
... ABSTRACT: Paracoccidioidomycosis is a systemic human mycosis caused by Paracoccidioides brasiliensis ...as experimental paracoccidioidomycosis ...infection. In these periods, fragments ... See full document
1
Therapeutic DNA Vaccine Encoding Peptide P10 against Experimental Paracoccidioidomycosis
... brasiliensis, is the most prevalent invasive fungal disease in South ...cause of death among infectious diseases in Brazil and PCM is responsible for more than 50% of deaths due ... See full document
9
Identification of potential cytokine pathways for therapeutic intervention in murine primary biliary cirrhosis.
... (PBC) is considered a model autoimmune disease, with the most highly directed and specific autoantibody in both murine and human autoimmunity, the anti-mitochondrial autoantibody ...However, ... See full document
11
Chloroquine is a zinc ionophore.
... for chloroquine, as evidenced by co-localization of zinc with the lysosome and the induction of apoptosis when cells were treated with the combina- tion of chloroquine and ...and ... See full document
6
Novel insights into disseminated candidiasis: pathogenesis research and clinical experience converge.
... occur in healthy people outside of hospitals. It is also incorrectly often said that most patients who develop disseminated candidiasis are ...infection) is indeed a well known risk factor for ... See full document
2
Rev. Soc. Bras. Med. Trop. vol.47 número1
... the in vitro antimalarial activity of tigecycline as an alternative drug for the treatment of severe ...A chloroquine-sensitive Plasmodium falciparum reference strain, a ... See full document
3
Adhesion Molecules as a Therapeutic Target in IBD
... hallmark of ulcerative colitis (UC) lesions is iniltration of the intestine by mononuclear cells, predominantly ...iniltration is the result of increased leukocyte recruitment and ... See full document
12
Therapeutic effect of ursolic acid in experimental visceral leishmaniasis
... Leishmaniasis is an important neglected tropical disease, affecting more than 12 million people world- ...effects in patients, justifying the search for new therapeutic ...compounds. In the ... See full document
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