[PDF] Top 20 Correction: Regulation of MYC Expression and Differential JQ1 Sensitivity in Cancer Cells.
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Correction: Regulation of MYC Expression and Differential JQ1 Sensitivity in Cancer Cells.
... across MYC with anti-C-terminal Brd4 ...analyzed in triplicate via real-time PCR and reported as the mean and standard deviation of the two ...representation of the promoter area ... See full document
2
Differential expression of MYC in H. pylorirelated intestinal
... role in the regulation of cell cycle progression and ...The MYC gene, located on human chromosome 8q24, encodes a transcriptional factor involved in proliferation, growth, ... See full document
7
KRAS mutation is a predictor of oxaliplatin sensitivity in colon cancer cells.
... -DDK-myc-COLO320DM cells treated with oxaliplatin for 72 hours was ...that of parental COLO320DM/KRAS G12V -DDK-myc-CO- LO320DM cells treated with irinotecan, 5FU, and ... See full document
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Lin28 mediates radiation resistance of breast cancer cells via regulation of caspase, H2A.X and Let-7 signaling.
... Lin28 and radioresistance remains unknown. In this study, we investigated the association of Lin28 with radiation resistance and identified the underlying mechanisms of action of ... See full document
6
1-Methyl-D-tryptophan potentiates TGF-β-induced epithelial-mesenchymal transition in T24 human bladder cancer cells.
... MT and TGF-β1 significantly decreased phospho-Akt levels, indicating that TGF-β-driven EMT in T24 cells is associated with the downregulation of this ...pathway. In many cell types, ... See full document
16
Differential expression of integrin subunits on adherent and nonadherent mast cells
... tion and that the differential expression of these molecules allows the migration and specific homing ...(7,29). In vivo, the cells can transit through different ... See full document
9
The chemokine CXCL16 and its receptor, CXCR6, as markers and promoters of inflammation-associated cancers.
... fixed and paraffin-embedded. Frozen tissue was fixed in formalin prior to ...DakoCytomation). In some cases, biotinylated rabbit anti-goat IgG secondary antibody was used, and detection was ... See full document
12
Editor’s Pick: PSMA-Specific Ligands in Prostate Cancer Diagnosis and Therapy
... domain of prostate-speciic membrane antigen: preclinical studies in nude mice bearing LNCaP human prostate ...generation of monoclonal and recombinant antibodies against cell-adherent prostate ... See full document
8
Down-regulation of myogenin can reverse terminal muscle cell differentiation.
... Down-regulation of myogenin caused cleavage of terminally differentiated myotubes into mononucleated product cells, which can reenter into the cell ...series of molecular experiments ... See full document
11
Immunoexpression analysis and prognostic value of BLCAP in breast cancer.
... that in urothelial carcinomas, in most cases, BLCAP protein expression was lost with tumor ...overexpressed in 20% of the cases, independently of the clinicopathological ... See full document
10
Loss of the urothelial differentiation marker FOXA1 is associated with high grade, late stage bladder cancer and increased tumor proliferation.
... source of bias is that the majority (18 out of 22) of Ta stage tumors were acquired from ...FOXA1 expression is uniformly positive in Ta stage tumors, it is important to point out that ... See full document
13
CXCR4 expression in prostate cancer progenitor cells.
... immersion in 4% paraformaldehyde, cryoprotected in 20% sucrose, frozen, and embedded in sucrose:OCT ...min in antibody buffer (50 mM NaCl, 50 mM Tris Base, 1% BSA, 100 mM L-Lysine, ... See full document
13
CITED2 and the modulation of the hypoxic response in cancer
... Structure of CITED2 and its interplay with hypoxia-inducible factors to modulate the response to ...representation of CITED2, hypoxia-inducible factor (HIF)-1α and ...members, and the ... See full document
19
Suppression of cellular immunity
... T cells; activation of immunoregulatory pathways, in which cancer cells actively inhibit tumor immunity by suppressing regulatory pathways that serve as “checkpoints” in immune ... See full document
7
Actin cytoskeleton regulation of epithelial mesenchymal transition in metastatic cancer cells.
... loss of the cell-cell adhesion molecule E-cadherin and disruption of cell-cell junctions as well as with acquisition of migra- tory properties including reorganization of the actin ... See full document
12
Perfil de expressão dos genes MYC, MYCN, TERT, ASPM e PRAME em Meduloblastoma
... the expression of genes MYC, MYCN and TERT in tumor fragments of pediatric medulloblastoma and correlate gene expression profiles with clinical ...Analysis ... See full document
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Estrogen-Responsive Genes Overlap with Triiodothyronine-Responsive Genes in a Breast Carcinoma Cell Line
... distribution, and reproduction in any medium, provided the original work is properly ...role in the progression and treatment of breast ...role of triiodothyronine (T 3 ) remains ... See full document
8
Receptor activator of NF-kB (RANK) expression in primary tumors associates with bone metastasis occurrence in breast cancer patients.
... high expression of RANK/RANKL/OPG in the primary tumor ...not in breast cancer) and propensity to develop bone metastasis ...lung, and prostate cancer) with high ... See full document
9
Proteomic interrogation of androgen action in prostate cancer cells reveals roles of aminoacyl tRNA synthetases.
... differences in the physico-chemical properties of the identified peptides ...strategy of using two different mass spectrometers, which differ both in their ionization source and ... See full document
12
Methyl Sulfone Blocked Multiple Hypoxia- and Non-Hypoxia-Induced Metastatic Targets in Breast Cancer Cells and Melanoma Cells.
... up-regulate and down-regulate expression and function of proteins, miR-210 and microtu- ...model of macrophenotypes (angiogenesis, Fe-S cluster biogenesis, cell cycle, ... See full document
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