[PDF] Top 20 Disturbance of copper homeostasis is a mechanism for homocysteine-induced vascular endothelial cell injury.

... Elevation of serum homocysteine (Hcy) levels is a risk factor for cardiovascular ...with copper (Cu) metabolism in vascular endothelial ...Hcy-induced disturbance ... See full document

... (Hcy) is an intermediate product of methionine metabolism in ...plasma homocysteine levels in healthy adults range from 5 to 15 ...plasma homocysteine is associated with the development ... See full document

... pathway is involved in the protective effect against high D- glucose induced HUVECs injury by silencing ...pathway, is involved. Activation of ERK1/2 is known to induce changes ... See full document

... use of ACE inhibitors or angiotensin receptor blockers (ARBs) during the previous week, 3) any contraindication to ACE inhibitor therapy, 4) severe arrhythmia, 5) level IV cardiac function or left ventricular ... See full document

... levels of VEGF in culture supernatants were detected when KU812 and HMC-1 cells were cultured in the presence of IL-9 (Table ...survival of mast cells and induces their production of ... See full document

... number of studies showed that HIF-1a, which has long been recognized as one of the important transcription factor that mediate cellular response to hypoxia, plays an important role in the regulation ... See full document

... Dwelling is one of the basic human needs and therefore it is found in all societies, but in various ...dwelling is among the basic needs of humans because it provides shelter against ... See full document

... identification of these targets was achieved using a RNA homogenized pool of vein sections, interacting on slides with 16,000 pre-determined human genes (Agilent Technologies ...veins of 16 ... See full document

... College of Obstetricians and Gynaecologists, Sociedade Portuguesa de Hipertensão, Maternidade Alfredo da Costa, Hospital São Teotónio – Viseu, Hospital São João – Porto, entre ... See full document

... lining of ECs in vivo is challenging, particularly when the cells undergo ...Because of the rate-limiting role of AGT in the RAS [24, 25], the release of an AGT protein as a progenitor ... See full document

... movement of cells out of the low-flow branch into the higher flow branch, thus leading to regression of the former and stabilization of the lat- ...onset of regression ...program ... See full document

... staining cell membranes, despite the compatibility that is described for each ...that is being ...ICAM2 is incompatible with these techniques, and an extremely sensitive epitope to work ... See full document

... Proliferating cell nuclear antigen; BUB1 = Budding uninhibited by benzimidazoles 1 homolog beta (yeast); MMP3 = Matrix metalloproteinase 3; VEGF = Vascular endothelial growth factor; DSP6 = Dual ... See full document

... which is par- ticularly important in producing ATP for organ recovery (Jassem et ...however, is dramatically magnified by a large number of events, such as oxygen free radical formation, release ... See full document

... results of this study show that β-TCP supports SC proliferation in addition to expression of the p75 LNGFR and S100-β phenotype, suggesting that the β-TCP material posed little-to-no toxicity to the SCs or ... See full document

... rings. Endothelial integrity was assessed by the degree of relaxation induced by 1 μmol/l acetylcholine (ACH) in the presence of contractile tone induced by phenylephrine ...the ... See full document

... mol/l of freshly prepared formaldehyde in ...the vascular system using a catheter placed into the left ventricle until the body was ...knowledge of the groups to which the animals ... See full document

... disease is one of the main causes of mortality and morbidity in diabetic ...effects of diabetes on myocardial capillary density and several serum angiogenic factors including nitric oxide, ... See full document

... oxidation of macromolecules such as DNA, proteins or membrane lipids is an important process during early carcinogenesis 5,14,15 ...state of high oxidative stress 16 . The magnitude of the ... See full document

... Copper is a trace element essential in several biological proces- ses, some of them important for physical activity, such as energy metabolism, iron homeostasis and antioxidant protection ... See full document