[PDF] Top 20 DNA damage by ochratoxin A in rat kidney assessed by the alkaline comet assay

... increases the incidence of uncom- mon tubular cell adenomas and of tubular cell carcinomas in rats of both sexes in a dose-dependent manner and the incidence and multiplicity of fibroadenomas ... See full document

... tested in blood cells, and its mutagenic effect was assessed in bone marrow and blood cells in ...mice. The comet assay was used to detect recent DNA damage, ... See full document

... The alkaline (pH >13) comet assay was performed with slight modiication from the method described byPu et ...obtained by veni puncturing from the individuals. Then, ... See full document

... assess the genetic toxicity of Guttiferone A, the present study was undertaken to investigate the genotoxic potential of this benzophenone isolated from seeds of Garcinia achachairu in terms ... See full document

... display the results that are related to the Frequency and the Index of damage, respectively, assessed by Comet Assay and as demonstrated, the group of ... See full document

... used in Dentistry because it is a specific and effective caries prophylactic ...especially by causing injury on genetic ...carcinogens. In this study, the potential DNA damage ... See full document

... for comet assay were kept under re- frigeration and protected from light during transport from the ICL to the Laboratory of Mutagenesis and Oncoge- netics at the University of Londrina, ... See full document

... occurrence in aquatic and terres- trial habitats makes them vulnerable to environmental change (Blaustein and Wake, 1990; Lips, ...measure the environmental impact of xenobiotics have used mainly larval ... See full document

... were the first to quantify DNA damage in cells using a microgel electrophoresis technique known as “single cell gel electrophoresis or comet ...assay”. In this method, ... See full document

... or Comet assay, as introduced by Singh et ...detects DNA strand breakage and alkali labile sites by measuring the migration of DNA from immobilized indi- vidual cell ... See full document

... The alkaline comet assay was performed by the method earlier described by Speit and Rothfuss ...of the cell suspension (hepatocytes and bone marrow mononuclear ... See full document

... among the European Union countries most devastated by forest fires each ...year. In the last three decades, more than ...studies in firefighters, particularly concerning genotoxicity ... See full document

... used by popular medicine in the western Amazon ...demonstrated the genotoxic safety of the popular use of this species, and owing to this, the present study aimed to perform an ... See full document

... Because the beams are composite, with a moment resistance much higher than the resistance of the joints, the mechanical damage is mainly due to non-linear behaviour of the ... See full document

... to DNA damage and survival upon UVC ...evaluate the impact of this radiation on the marine organisms and ...new DNA damage detection assay was developed and optimized for ... See full document

... after the procedure and 3 and 24 h later. The basal level of damage and the radioinduced damage were higher in lymphocytes from breast cancer patients than in lymphocytes ... See full document

... tree, the seeds of which produce a commercially valuable oil that is used in folk medi- cine and in the cosmetic ...and in- sect-repellant actions. However, virtually nothing is known ... See full document

... for the experiment. The salinity was 0.6 at the time of collection and was maintained at 26 ± 1˚C during the ...accommodated in 10 L aquaria and maintained for seven days on filtered ... See full document

... find the area of sector the angle made by the chord (that is chord which divides the circle) is ...But in the below method we find the ratio of the segments ... See full document

... analysis, kidney tissue samples were fixed in 10% formaldehyde and prepared for routine paraffin ...prepared by using a microtome (Leica RM2255) and stained with Hematoxylin and Eosin (H&E) dye, ... See full document