[PDF] Top 20 Effect of phospholipase A2 inhibitors during infection caused by Leishmania (Leishmania) amazonensis

... tion of macrophages’ intracellular environments. LPG is one of the main glycoconjugate of Leishmania promasti- gotes, and is involved in the protection of the parasite not only from the ... See full document

... stage of the ...macrophages during human infection are more sensitive to lactacystin than promastigotes developing in culture medium [49], which may be explained by a distinct action of ... See full document

... against Leishmania than the BAE in solution when applied to cultures of previously infected macrophages that contained amastigotes in their ...mechanisms of L. amazonensis, which result in a ... See full document

... proven by reducing the percentage of transport of the electrolytes sodium (Na +), (K +) and chloride (Cl ¯ ) at the concentrations studied, regardless of the reduction of ...observed ... See full document

... efficacy of serological methods for diagnosing ...culling of healthy animals, or false-negative results, contributing towards maintaining the reservoirs in endemic áreas 25 ...serodiagnosis of ... See full document

... year of study (2012), two autochthonous cases of CL were reported in the municipality of ...cases of CL. Between January-July 2015, only one case of mucosal leishmaniasis was reported ... See full document

... range of IC 50 /24h 1.6 to 7.8 µg/ ml for L. amazonensis and ...amount of fetal calf serum. This fact would result in a lower availability of the compound, since some serum protein or protein ... See full document

... A leishmaniose tegumentar americana e as dermatofitoses sao doenças que provocam lesões cutâneas Os medicamentos disponiveis para o tratamento das doenças apresentam efeitos adversos, por isso a necessidade de uma busca ... See full document

... subgênero Leishmania(Viannia), permitindo, no entanto, distinguir Leishmania ...(L.) amazonensis) de Leishmania ...subgênero Leishmania (Viannnia), diferenciando assim Leishmania ... See full document

... detected by direct immunofluorescence in the tissue from de- pleted mice during the first week after infec- tion, in spite of complement recovery in the sera by the 7th day of ... See full document

... Em áreas consideradas endêmicas para leishmaniose canina, cães com histórico de claudicações intermitentes, e lesões ósseas líticas radiográficas, sugestivas de osteomielite, devem ser encaminhados para realização do ... See full document

... de Leishmania existentes, ocorre uma divisão de acordo com as características clínicas da doença que elas causam, sendo divididas entre dermatotrópicas e ...pela Leishmania (Leishmannia) infantum Novo ... See full document

... injection of SSPHE reduced the parasite load in the infected footpads and draining lymph nodes, but also induced a signifi- cant, progressive increase in footpad thickness through- out treatment, whereas oral ... See full document

... proceeding of use of current available drugs for the treatment of leishmaniasis have motivated the search for new therapeutical ...aim of this work was to evaluat the effect of ... See full document

... extracts of Brazilian propolis reduced L. amazonensis infection in macrophage ...extract of Brazilian propolis samples have been typified in four groups (Marcucci ...concentration of ... See full document

... causes of illness among the poorest populations living in developing ...one of six major infectious diseases, with a high detection rate and the capacity to produce deformi- ...variety of agents, ... See full document

... clone Lacys24 pelo programa AMPHI mostrou três motivos de ligação ao MHC de classe II e um ao MHC de classe I na seqüência desse clone (Figura 5). Esses resultados indicam a possibilidade de participação de linfócitos T ... See full document

... against Leishmania infections but controversial results have been reported when different antigens are co-administered in combined vaccination ...with A2 or nucleoside hydrolase (NH) antigens was previously ... See full document

... vectors of these diseases; the transmission of these infections in sub-tropical regions, although recognized, represents only a small fraction of ...acquisition of new drugs, and many ... See full document

... 42.86% of protection was obtained in the group of mice vaccinated with association of proteins of gp63+46+22kDa, ...57.14% of protection was demonstrated with ...vaccine of ... See full document