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[PDF] Top 20 Elimination of self-reactive T cells in the thymus: a timeline for negative selection.

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Elimination of self-reactive T cells in the thymus: a timeline for negative selection.

Elimination of self-reactive T cells in the thymus: a timeline for negative selection.

... The elimination of autoreactive T cells occurs via thymocyte apoptosis and removal by thymic phagocytes, but the sequence of events in vivo, and the ... See full document

14

Continuous activation of the CD122/STAT-5 signaling pathway during selection of antigen-specific regulatory T cells in the murine thymus.

Continuous activation of the CD122/STAT-5 signaling pathway during selection of antigen-specific regulatory T cells in the murine thymus.

... inducer of Bcl-2 and Bcl-xL [41], which are crucial anti-apoptotic molecules, STAT-5 may also be involved in the survival of some thymocytes recognizing ...amount of time for the ... See full document

8

Bringing you negative selection, live and in color.

Bringing you negative selection, live and in color.

... study negative selection mainly in single-cell suspensions of dissociated thymic tissue, but Dzhagalov et ...interested in how T cells behave during negative ... See full document

1

Triggering the TCR developmental checkpoin activates a therapeutically targetable tumor suppressive pathway in T-cell leukemia

Triggering the TCR developmental checkpoin activates a therapeutically targetable tumor suppressive pathway in T-cell leukemia

... T cells mature in the thymus following a highly orches- trated process controlled by both cell-intrinsic ...expression in DP thymocytes allows recognition of specifi c ... See full document

15

Development of regulatory T cells in the human thymus : one step beyond =desenvolvimento de células T reguladoras no timo humano

Development of regulatory T cells in the human thymus : one step beyond =desenvolvimento de células T reguladoras no timo humano

... Differentiation of blood-derived T cell progenitors to mature CD4 or CD8 T cells in the thymus is accomplished by sequential development through a series of stages ... See full document

168

Positive selection of natural poly-reactive B cells in the periphery occurs independent of heavy chain allelic inclusion.

Positive selection of natural poly-reactive B cells in the periphery occurs independent of heavy chain allelic inclusion.

... Most of the naturally-occuring autoantibodies are poly-reactive and exist in healthy individ- uals [18, ...5~20% of long-lived B cells are autoreactive in humans ... See full document

15

Self-glycolipids modulate dendritic cells changing the cytokine profiles of committed autoreactive T cells.

Self-glycolipids modulate dendritic cells changing the cytokine profiles of committed autoreactive T cells.

... impact of glycolipids of non-mammalian origin on autoimmune inflammation has become widely ...that the naturally occurring mammalian glycolipids, sulfatide and b-GalCer, affect the ... See full document

7

Histone deacetylase inhibitors impair the elimination of HIV-infected cells by cytotoxic T-lymphocytes.

Histone deacetylase inhibitors impair the elimination of HIV-infected cells by cytotoxic T-lymphocytes.

... that the net effects of HDACi treatment on HIV- specific T-cells in the majority of our functional assays involved contributions from both of these modes of ... See full document

19

Determination Of Longevity Of Teeth In Buckets Of Loading Equipment In Coal Mines - A Case Study

Determination Of Longevity Of Teeth In Buckets Of Loading Equipment In Coal Mines - A Case Study

... Abstract: The life of bucket teeth in shovel and dragline deployed in handling of overburden rock is an important contributor to the stores cost and is also responsible for ... See full document

11

A Method To Find The Area Of Sector Without The Usage Of Angle Made By The Chord

A Method To Find The Area Of Sector Without The Usage Of Angle Made By The Chord

... find the area of sector the angle made by the chord (that is chord which divides the circle) is ...But in the below method we find the ratio of the ... See full document

2

The Influence Of CSR Awareness On Consumer Purchase Decision Of A Telecommunication Network In Ghana A Case Of La Nkwantanag Madina Municipality

The Influence Of CSR Awareness On Consumer Purchase Decision Of A Telecommunication Network In Ghana A Case Of La Nkwantanag Madina Municipality

... investigated the effect of associated CSR practices on consumers and presented similar ...findings. The CSR activities mentioned in the research are, for instance, environmental ... See full document

9

Assessment Of Some Acceleration Schemes In The Solution Of Systems Of Linear Equations.

Assessment Of Some Acceleration Schemes In The Solution Of Systems Of Linear Equations.

... systems of linear equations Ax = b, where A, b are known matrices and x is a vector of ...Systems of linear equations play a prominent role in economics, engineering, physics, chemistry, ... See full document

8

CONTINUOUS CREATION IN THE PROBABILISTIC WORLD OF THE THEOLOGY OF CHANCE

CONTINUOUS CREATION IN THE PROBABILISTIC WORLD OF THE THEOLOGY OF CHANCE

... question in the positive: Yes, He can, because He is the most perfect being and His omnipotence is absolutely ...underlying the answer to the last question is that the risk is ... See full document

16

The Economics of Sub-optimal Policies for Traffic Congestion

The Economics of Sub-optimal Policies for Traffic Congestion

... tax in order to alleviate the negative effects of traffic ...matter of internalizing a negative ...problem in cities across the world, and a congestion tax is ... See full document

27

An Analysis Of The Difference In Gender Level Of Cassava Production And Access To Land In Abia State Nigeria

An Analysis Of The Difference In Gender Level Of Cassava Production And Access To Land In Abia State Nigeria

... employed in sample selection. In the first stage, the three agricultural zones in the state were purposively ...Ohafia. In the second stage three local ... See full document

5

Application of time-series analysis for prediction of molding sand properties in production cycle

Application of time-series analysis for prediction of molding sand properties in production cycle

... for the 10 cases with largest pre- diction errors, also a regression tree model, based on the C&RT algorithm [8], was ...utilized. The regression trees are non- parametric, non-linear models ... See full document

5

The Existence Of Leading Islands Securing And The Border Areas Unitary State Of Indonesia An Analysis In Law Perspective

The Existence Of Leading Islands Securing And The Border Areas Unitary State Of Indonesia An Analysis In Law Perspective

... Abstract: The research was carried with the aim to discover the existence of securing the foremost islands and state border region of the Republic of Indonesia ... See full document

4

Assessment Of NPK In Human Male And Female Urine For Its Fertilising Potential In Agriculture

Assessment Of NPK In Human Male And Female Urine For Its Fertilising Potential In Agriculture

... irrespective of the type of treatment ...is the likelihood of cross-contamination with the use of urine separating (Ecosan) toilets ...part of the total ... See full document

9

Managament quality of tools in the planned housing casting

Managament quality of tools in the planned housing casting

... Subbotko, Methods of distribution of tool at units based on TM software of Guhring, Production Engineering Wroc ł aw University of Technology,(2006) 273- 280 (in Polish).. Bocheński, C[r] ... See full document

4

The Impact of the Expansion of the Bolsa Familia Program on the Time Allocation of Youths And Their Parents Lia Chitolina Miguel Nathan Foguel Naercio Menezes-Filho

The Impact of the Expansion of the Bolsa Familia Program on the Time Allocation of Youths And Their Parents Lia Chitolina Miguel Nathan Foguel Naercio Menezes-Filho

... As the multinomial model is non-linear, the marginal effect of the treatment in a DID model is not the marginal impact of the interaction between time and ... See full document

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