[PDF] Top 20 Expression of EpCAM in uveal melanoma
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Expression of EpCAM in uveal melanoma
... class of intact antibodies. The two binding sites of this antibody are against EpCAM positive tumor cells and T cells ...results in higher tumor killing than the mono- clonal antibodies ... See full document
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Targeted methylation of the epithelial cell adhesion molecule (EpCAM) promoter to silence its expression in ovarian cancer cells.
... silencing of EpCAM after the expression of a Zinc finger fused repressor Kruppel-associated box (SKD) domain, which was delivered with a retroviral vector ...reduction of proliferation ... See full document
8
microRNA-155, induced by interleukin-1ß, represses the expression of microphthalmia-associated transcription factor (MITF-M) in melanoma cells.
... role in the immune response and modulate several pathways [12]. In the tumor microenvironment, they have a significant influence on the progression of the tumor and the anti-tumor immune response ... See full document
18
High interstitial fluid pressure is associated with low tumour penetration of diagnostic monoclonal antibodies applied for molecular imaging purposes.
... mRNA expression levels for EpCAM of twelve human cancer cell lines were analyzed in vitro by ...(except of melanoma cell lines) of the different entities had similar ... See full document
11
Epcam, CD44, and CD49f distinguish sphere-forming human prostate basal cells from a subpopulation with predominant tubule initiation capability.
... inclusive of ducts/acini composed of both basal and luminal ...capability of putative S/P populations in mouse and human [4,21,22]. In these assays, total or fractionated cells obtained ... See full document
10
In vitro characterization and inhibition of the CXCR4/CXCL12 chemokine axis in human uveal melanoma cell lines
... amount of evi- dence suggesting that the CXCR4/CXCL12 chemokine sig- naling axis may play an integral role in the metastatic progression of many tumor ...expressed in certain tumors such as ... See full document
7
Rapid and non-enzymatic in vitro retrieval of tumour cells from surgical specimens.
... strong expression of EpCAM in approximately 95–100% of cells (Figure 3A, upper left ...This expression pattern of EpCAM was similarly observed in explanted ... See full document
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Aspectos psicológicos e qualidade de vida em pacientes com melanoma uveal durante o processo de tratamento por remoção do bulbo ocular.
... sions in the individual with uveal melanoma and surgical indi- cation in three phases: diagnosis and preoperative, postsur- gery and late ...Quality of Life Questionaire SF-36. Results: ... See full document
6
Periostin Is a Key Niche Component for Wound Metastasis of Melanoma.
... 3) of the patient. Analysis of 54,675 probe sets revealed that 539 genes exhibited a > 4-fold increase in expression level in the metastatic lesion compared with the primary lesion ... See full document
17
Up-regulation of hepatoma-derived growth factor facilitates tumor progression in malignant melanoma [corrected].
... assay in a Boyden chamber (48-well plate), using a polycarbonate filter (8 mm pore size; Nucleopore, Costar, Cambridge, MA, USA) as previously Figure ...Effects of HDGF overexpression or gene silencing on ... See full document
9
Methyl Sulfone Blocked Multiple Hypoxia- and Non-Hypoxia-Induced Metastatic Targets in Breast Cancer Cells and Melanoma Cells.
... 90% of cancer ...caused in part by the metastatic cell niche: ...metabolism of hypoxic breast cancer and melanoma cells by altering several metabolic functions of the ...decreased ... See full document
22
Down-regulation of the interferon signaling pathway in T lymphocytes from patients with metastatic melanoma.
... gene expression is regulated by the JAK- STAT (Janus kinase–signal transduction and activator of transcription) signaling ...Binding of type I IFNs, such as IFN-a and IFN-b, to their specific receptor ... See full document
15
Improved antimelanogenesis and antioxidant effects of polysaccharide from Cuscuta chinensis Lam seeds after enzymatic hydrolysis
... purpose of this research was to investigate the antimelanogenic activity of ECPS and CPS in B16F10 melanoma ...The in vitro antioxidant activity was assessed by their ferric iron ... See full document
8
The regulation of miRNA-211 expression and its role in melanoma cell invasiveness.
... UTR of the LacZ gene in pcDNA6/V5-His/LacZ (Invitrogen) using the 59 NotI and 3 9 AgeI restriction sites and reconfirmed by sequencing ...9UTR of KCNMA1 was mutated using the primers: KC Mut For- ... See full document
14
Melanoma primário da mucosa oral: estudo dos aspectos clínico-patológicos e da expressão...
... mucosal melanoma is a rare aggressive ...molecule expression profiles. The present study analyzed the expression of integrins, claudins, and immunoglobulin-like adhesion molecules in ... See full document
143
Analysis of alpha-synuclein in malignant melanoma - development of a SRM quantification assay.
... malignant melanoma shows a steady increase in the incidence among cancer ...Malignant melanoma represents a cancer type where currently no biomarker or diagnostics is available to identify disease ... See full document
9
EPISCLERAL BRACHYTHERAPY IN PORTUGAL::
... Cases of circumpapillary or peripapillary melanomas that could not be correctly irradiated with EBT were offered proton beam ...possibility of adequate irradiation with EBT plaques were offered ...evidence ... See full document
10
Simulação e análise dosimétrica de protonterapia e íons de carbono no tratamento do melanoma uveal.
... evaluation of carbon ion radiotherapy as compared with proton ...implemented in the Siscodes system (computer system for dosimetry in radiation therapy) was utilized to generate and superimpose depth ... See full document
7
Abnormal placental development and early embryonic lethality in EpCAM-null mice.
... viable EpCAM 2/2 pups were obtained. Examination of embryos obtained after timed heterozygote matings revealed that 2/2 embryos implanted, and that control and EpCAM-deficient embryos could not be ... See full document
9
Efeitos do ranibizumabe e do amfenac nas habilidades funcionais e na radiossensibilidade de células de melanoma uveal
... effects of ranibizumab and amfenac in human uveal melanoma cell lines and to explore the ability of these compounds to sensitize uveal melanoma cells to radiation ...human ... See full document
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