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The expression of p53 protein in patients with multiple myeloma

The expression of p53 protein in patients with multiple myeloma

... proteina p53 ispitivana je na parafin­ skim isečcima kostne srži dobijenim trepanobiop­ sijom grebena ilijačne kosti, uz upotrebu trokara po Jamšidi (Jamshid­a) u lokalnoj ...proteinu p53 (DAKO, M7001 klon ... See full document

5

Pharmacovigilance of patients with multiple myeloma being treated with bortezomib andor thalidomide

Pharmacovigilance of patients with multiple myeloma being treated with bortezomib andor thalidomide

... frequency of side effects. Although we have not assessed the impact on quality of life of our patients, we infer that such events have a negative impact, leading us to believe that ... See full document

6

Clinics  vol.63 número2

Clinics vol.63 número2

... treating patients with multiple myeloma or metastatic breast cancer based on study findings that pamidronate reduces the risk of skeletal ...complications. In 2002, ... See full document

4

Stress-induced alternative splice forms of MDM2 and MDMX modulate the p53-pathway in distinct ways.

Stress-induced alternative splice forms of MDM2 and MDMX modulate the p53-pathway in distinct ways.

... For the immunoprecipitation (IP) of myc-tagged proteins LacZ or MDM2-ALT1 or MDMX-ALT2 and also for the reciprocal IP of endogenous MDM2, MCF7 cells were transfected with the ... See full document

11

Long-time treatment by low-dose N-acetyl-L-cysteine enhances proinflammatory cytokine expressions in LPS-stimulated macrophages.

Long-time treatment by low-dose N-acetyl-L-cysteine enhances proinflammatory cytokine expressions in LPS-stimulated macrophages.

... role of p53 as a tumor suppressor is the induction of cell cycle arrest of DNA-damaged cells to prevent proliferation of abnormal ...increased expression of ... See full document

10

The expression and significance of p53 protein and Ki-67 protein in pterygium

The expression and significance of p53 protein and Ki-67 protein in pterygium

... disease of the conjunctiva, however, the presence of tumor markers in pterygium reinforces the hypothesis that this lesion is similar to ...Inactivation of p53 ... See full document

5

Multiple Myeloma in a Patient with Acromegaly

Multiple Myeloma in a Patient with Acromegaly

... In our case, the patient’s serum hemoglobin level ...at the cutoff level for symptomatic MM and her se- rum calcium level ...below the cutoff, suggesting that the risk of ... See full document

6

Multiples aberrant phenotypes in multiple myeloma patient expressing CD56-, CD28+,CD19+

Multiples aberrant phenotypes in multiple myeloma patient expressing CD56-, CD28+,CD19+

... that the expression of aberrant antigens in myeloma plasma cells (MPCs) is a common ...feature. The most frequent aberrant antigens in MPCs are: CD56 (75%) and CD117 ... See full document

2

Autologous stem cell transplantation improves quality of life in economically challenged, Brazilian multiple myeloma patients

Autologous stem cell transplantation improves quality of life in economically challenged, Brazilian multiple myeloma patients

... characterize the impact of multiple myeloma on the quality of life of patients treated in two public institutions in Sa˜o Paulo State, Brazil, using a ... See full document

5

Peripheral neuropathy in people with multiple myeloma

Peripheral neuropathy in people with multiple myeloma

... treatment with chemothera- py regimens. Predominance was of elderly retired ...men. The most common chemotherapy regimen was VDC and there was no association between regimens used and PN after ... See full document

7

Primary systemic amyloidosis associated with multiple myeloma

Primary systemic amyloidosis associated with multiple myeloma

... analysis of aminoacids demons- trated that in systemic amyloidosis associated with multiple myeloma, fibrils are composed of an AL pro- tein (light chain amyloidosis ... See full document

4

Characterization of the Toll-like receptor expression profile in human multiple myeloma cells.

Characterization of the Toll-like receptor expression profile in human multiple myeloma cells.

... our expression analyses indicate that HMCLs display a broad range of TLRs at gene and protein ...analysis of mRNA alone may not provide a correct prediction of functional TLR ... See full document

9

BIOCHEMICAL PROFILE AND ELECTROPHORETIC PATTERN IN  MULTIPLE MYELOMA PATIENTS

BIOCHEMICAL PROFILE AND ELECTROPHORETIC PATTERN IN MULTIPLE MYELOMA PATIENTS

... encountered in multiple myeloma patients. Protein electrophoresis should be undertaken whenever multiple myeloma, is ...Serum protein electrophoresis (SPE) is ... See full document

5

Multiple myeloma with cells typically seen in storage diseases

Multiple myeloma with cells typically seen in storage diseases

... Serum protein electrophoresis revealed an M-protein spike of ...g/L in the beta region. The concentrations of the IgG, IgA and IgM immunoglobulins were ... See full document

1

A Bmi1-miRNAs cross-talk modulates chemotherapy response to 5-fluorouracil in breast cancer cells.

A Bmi1-miRNAs cross-talk modulates chemotherapy response to 5-fluorouracil in breast cancer cells.

... miR-200c expression has been linked with cancer progression and chemotherapy resistance via EMT process and CDCs regulation ...loss of miR-200c expression contribute to drug resistance ... See full document

10

Rev. Bras. Hematol. Hemoter.  vol.27 número1

Rev. Bras. Hematol. Hemoter. vol.27 número1

... most of which were in the accelerated and the blastic crisis phases of the disease and these alterations were correlated with the p53 protein ... See full document

2

Tumor suppressor p53 protein expression : prognostic significance in patients with lowrisk  syndrome

Tumor suppressor p53 protein expression : prognostic significance in patients with lowrisk syndrome

... In the present study, the frequency of p53 expression at diagnosis was ...These patients showed features of poor prognosis, such as more advanced age at diagnosis ... See full document

6

Confirmation of the utility of the International Staging System and identification of a unique pattern of disease in Brazilian patients with multiple myeloma

Confirmation of the utility of the International Staging System and identification of a unique pattern of disease in Brazilian patients with multiple myeloma

... years, the estimat- ed proportions of survival for patients in DSS stages I, II and III were ...respectively. The survival curves for patients in ISS stages I, II and III ... See full document

2

Expression of p53 protein in pituitary adenomas

Expression of p53 protein in pituitary adenomas

... embedded in paraffin, stored in a bank of adenomatous pituitary tissue, were cut and sections were mounted on glass slides prepared with ...organosilane. The immuno- histochemical study ... See full document

5

Expression of p53 protein in Barrett’s adenocarcinoma and adenocarcinoma of the gastric cardia and antrum

Expression of p53 protein in Barrett’s adenocarcinoma and adenocarcinoma of the gastric cardia and antrum

... studies of esophageal and gastric adenocarcinomas have shown a very high rate of p53 gene mutation and/or protein overexpression, but the influence of the tumour site upon ... See full document

7

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