[PDF] Top 20 A general definition and nomenclature for alternative splicing events.
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A general definition and nomenclature for alternative splicing events.
... (iii), splicing graphs as a non-redundant data structure have gained popularity in AS over the recent years, but definitions vary across ...them and/or to allow the analysis of AS. Heber and ... See full document
14
Identification of rare alternative splicing events in MS/MS data reveals a significant fraction of alternative translation initiation sites
... the definition of a proper false discovery rate when adding entries in a database ad ...Mascot and MaxQuant (Andromeda) have proof-check algorithms to quantify FDR rate, incorrect MS/MS information might ... See full document
15
Functional and molecular characterization of SR45, a plant-specific splicing factor involved in sugar and stress signaling in Arabidopsis thaliana
... the splicing machinery. Two studies by Green and co- workers have shown that the RS domain can also directly contact with the branch point site and the 5’ splice site to promote splicing (Shen ... See full document
238
Analysis of the contribution of alternative splicing to glioma subtype definition
... drivers and various to be associated with glioma, like ErbB tyrosine kinase receptor genes, cell proliferation related genes such as CDKN2C or MDM2, and the DNA CpG demethylator enzyme encoding ...41 ... See full document
114
Strategies for identifying RNA splicing regulatory motifs and predicting alternative splicing events.
... mRNA. Splicing of pre-mRNAs occurs in a two-step reaction (Figure ...intron, and this 59 end is linked to the branch point, which is typically in close proximity upstream of the 39 end of the ...ligated, ... See full document
10
A pan-cancer analysis of transcriptome changes associated with somatic mutations in U2AF1 reveals commonly altered splicing events.
... the splicing events associated with U2AF1 S34F mutations in AML also show enrichment of cassette exons and alternative 3 9 splice sites (Figure ...manner and those instances are cleared ... See full document
10
Design of static var compensators using a general reactive energy definition
... energy definition from the Conservative Power Theory (CPT) [8], which is a conservative term and remains valid under unbalanced, nonsinusoidal or variable frequency ...reactive and load imbalance ... See full document
6
Intrinsic disorder in the BK channel and its interactome.
... skeletal and smooth muscles, exocrine cells, and sensory cells of the inner ...distribution, and potential mechanisms of intrinsic disorder in 27 BK channel variants from mouse cochlea, 104 ... See full document
15
Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome.
... kinetics and synaptic transmission in Mecp2 KO cortical neurons can be reversed by ...WT and Mecp2 KO cortical ...WT and Mecp2 KO cortical ...WT and Mecp2 KO cortical neurons with or without ... See full document
25
A statistical method for the detection of alternative splicing using RNA-seq.
... metric and its skewed distribution over ESJ and ...exon, and the right part (filled in blue) is from the first 21 bp of the downstream ...(right), and the mismatch nucleotides are ...Exon ... See full document
8
Characterizing the Genetic Basis for Nicotine Induced Cancer Development: A Transcriptome Sequencing Study.
... gene and has unknown function, but it is reported to be overexpressed in lung carcinoma ...neuroblastoma, and colorectal ...response and is a positive regulator of TNF-a and IL-8 ...sTREM1 ... See full document
8
2º Painel - Produção e disseminação de pesquisa aplicada
... Events (seminars, workshops, lectures) open to general public.. Courses open to general public.[r] ... See full document
18
Differential temporal and spatial progerin expression during closure of the ductus arteriosus in neonates.
... fetus and neonate into the fibrous structure of the ligamentum arteriosum is characterized by intimal thickening without an atheromatous ...media and intima are due to CN ...DA and vascular pathology ... See full document
7
Laboratory of Plant Molecular Biology
... shorter and does not include the DNA-binding ...the alternative transcripts revealed that the shortest splice variant accounts for a role of PIF6 in the control of seed dormancy in Arabidopsis, whereas both ... See full document
265
A Computational Platform for Assessing the Impact of Alternative Splicing in Cancer
... done and are composed by a set of steps (a ...necessary, and the pipeline would be stored as a single software ...file(s) and get the results without the need to call several programs and with ... See full document
82
Identification of a novel TDRD7 isoforms
... membrane and in cytoplasmic structures called chromatoid bodies [5, ...scopy and anti-TDRD7 (E6) monoclonal antibody for more precise studying TDRD7 intracellular localizati- ...zone and in the ... See full document
7
The influence of social media communication on consumer's attitudes and behavioral intentions concerning brand-sponsored events
... firms and users are involved in creating and disseminating brand-related content (Bambauer-Sachse & Mangold, ...positioning and creative idea, and it is initiated by the ...information, ... See full document
20
Integrative annotation of 21,037 human genes validated by full-length cDNA clones.
... mean and median lengths of predicted ORFs were calculated for the 19,574 H-Inv ...bp and 806 bp, respectively (Table ...eukaryotes, and are inconsistent with estimates reported previously (Shoemaker ... See full document
20
Alternative splicing of sept9a and sept9b in zebrafish produces multiple mRNA transcripts expressed throughout development.
... I and II are a result of sept9a transcript inhibition ...functions, and that over-expression of only sept9a_tv1 cannot compensate for the loss of multiple ...artifact and one caused by knocking-down ... See full document
7
Small molecule amiloride modulates oncogenic RNA alternative splicing to devitalize human cancer cells.
... activities and localization of SR proteins ...proteins and hence regulation of AS [39,40]. Our finding of un-phosphorylated and hypo-phosphory- lated ASF/SF2 in amiloride-treated cancer cells ... See full document
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