[PDF] Top 20 Genetic Aspects of Premature Ovarian Failure

... renal failure or SF1 mutations associated with adrenal ...disorders of DNA repair are associated with gonadal dysgenesis in females, as it is the case for Ataxia tele- angiectasia, Nigmegen breakage syn- ... See full document

... use of drugs affecting bone metabolism (glucocorticoids, thyroxine, bisphosphonates, menopause replacement ...diagnosis of POF was made according to age (<40 years), the length of amenorrhea ... See full document

... number of environmental contaminants that have endocrine disrupting activity, and these can become a major public health ...prevalence of some non-communicable diseases, such as obesity, diabetes, thyroid ... See full document

... control of steroidogenesis [29]. The allelic reduction of Dlx5 and Dlx6 in the mouse is associated with a POF-like phenotype, with an early reduction of fertility and a rapid and premature ... See full document

... occurrence of spontaneous wheals for more than six weeks, has been associated with autoimmune ...sociation of CSU, Graves’ disease, and premature ovarian ...signs of hyperthyroidism for ... See full document

... effect of AFSCs, we transplanted EGFP-AFSCs directly into bilateral ovaries of mice with POF six weeks after ...ovaries of CTx-saline- and CTx-AFSCs-mice, during the Figure ...Characterization ... See full document

... cortex of the ...ovaries of germ ...number of follicles in one ovary is similar to number in the other ovary; however, there are large differences among individuals in total number of ... See full document

... review of medical records of the karyotype analysis of 65 women with POI who were referred by clinicians to the Medical Genetics Department of the Bezmi- alem Vakif University Hospital from ... See full document

... 5-20% of reproductive age ...pathogenesis of PCOS is not fully elucidated, but four aspects seem to contribute to the syndrome to different degrees: increased ovarian and/or adrenal androgen ... See full document

... determine ovarian safety. Small num- bers of young persons represented in research, hormonal usage in older females’ studies, vaccine report card limita- tions, omission of a true placebo, ... See full document

... etiologies of POI (genetic, chromosomal, infectious, and iatrogenic causes), the etiology cannot be identiied in most patients and this is referred to as idiopathic POI; up to 30% of idiopathic cases ... See full document

... incidence of the G679A mutation in exon 2 of the gene inhibin alpha (INHA), in women with secondary amenorrhea and diagnosis of premature ovarian insufficiency, and in ...sample ... See full document

... importance of the genetic characterization of these patients, both at the chromosomal and molecular ...understanding of the biological mechanisms associated with ...evaluation of their ... See full document

... aim of the present study was to identify the risk factors for ovarian failure in patients with systemic lupus ...developed ovarian failure were compared to those who did not. ... See full document

... fect of the expansion itself abnormally recruiting RNA- binding proteins, thus generally impeding the availability of these factors, has been considered as an explanation for the neurological impairment ... See full document

... Premature ovarian failure (POF), also known as premature ovarian insufficiency (POI), typi- cally is defined by elevated serum FSH levels prior to the age of 40 years ...1% ... See full document

... Concerning the aneuploidy frequency (hypodiploid and hyperdiploid cell frequencies), we also found no significant difference between the POF and control groups ( Table I ). Analysis of c[r] ... See full document

... [r] ... See full document

... prevalence of ovarian cysts, fatty liver disease, and bone fractures did not differ between women with and without ...prevalence of type 2 diabetes mellitus and incidence of ovarian and ... See full document

... before ovarian transplantation, animals were randomly allocated into ive groups, with 10 animals each, according to the ...doses of 150mg/kg, 300mg/ kg, 600mg/kg or 1200mg/kg - NAC150, NAC300, NAC600 and ... See full document