[PDF] Top 20 Genetic and epigenetic mechanisms involved in regulation of STEAP1 gene expression in LNCaP prostate cancer cells
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Genetic and epigenetic mechanisms involved in regulation of STEAP1 gene expression in LNCaP prostate cancer cells
... Prostate cancer is the second most frequently diagnosed type of cancer and the fifth leading cause of cancer death in men ...worldwide. Prostate ... See full document
78
Regulation of STEAP1 gene and its clinical significance in human prostate cancer
... that STEAP1 is overexpressed in several kinds of tumors, but the mechanisms underlying its overexpression remain to be ...if STEAP1 expression would be regulated by ... See full document
224
Epigenetic and oncogenic regulation of SLC16A7 (MCT2) results in protein over-expression, impacting on signalling and cellular phenotypes in prostate cancer
... SLC16A7 gene. Recent studies pointed to a consistent overexpression of MCT2 in prostate cancer (PCa) suggesting MCT2 as a putative biomarker and molecular ...importance of ... See full document
10
Transcriptional and epigenetic regulation of KIAA1199 gene expression in human breast cancer.
... (MatInspector and Alibaba2) to predict transcription factor binding sites based on DNA ...elements in the KIAA1199 promoter, including AP-1, NF-kB, and Twist-1, which are situated in the ... See full document
15
Expression of STEAP1 and STEAP1B in prostate cell lines, and the putative regulation of STEAP1 by post-transcriptional and post-translational mechanisms
... STEAP1 gene is overexpressed in several kinds of tumors, particularly in prostate ...Besides STEAP1, there is another related gene, STEAP1B, which may encode two ... See full document
10
The in vitro and in vivo anti-cancer activities of a standardized quassinoids composition from Eurycoma longifolia on LNCaP human prostate cancer cells.
... Human prostate cancer, LNCaP and PC-3 cells, human normal prostate, RWPE-1 cells and human normal liver, WRL 68 cells were purchased from the American Type ... See full document
21
Sodium butyrate induces growth inhibition and apoptosis in human prostate cancer DU145 cells by up-regulation of the expression of annexin A1.
... roles in apoptosis, proliferation, and cancer ...deal of controversy still exists regarding the expression of ANXA1 in different types of ...the expression ... See full document
8
Transcriptional and epigenetic regulation of KIF14 overexpression in ovarian cancer.
... 5 cells were cultured, and the protein- DNA complexes cross-linked with 1% formaldehyde (final concentration), followed by nuclear fractionation and DNA shearing via ...control) and IgG ... See full document
13
Mechanisms of human telomerase reverse transcriptase (hTERT) regulation: clinical impacts in cancer
... controlling of hTERT gene is complex and includes regulation at multiple levels by various posi- tive and negative factors or ...cloning of hTERT promoter and identi- ... See full document
12
Loss of somatostatin receptor subtype 2 in prostate cancer is linked to an aggressive cancer phenotype, high tumor cell proliferation and predicts early metastatic and biochemical relapse.
... subtype in normal human tissues. SSTR2 expression is differentially regulated in various tumor types and therapeutic somatostatin analogs binding to SSTR2 are in clinical ...use. ... See full document
10
Mechanisms of Hypoxic Up-Regulation of Versican Gene Expression in Macrophages.
... ability of DFO, but not cobalt chloride, to up-regulate versican mRNA suggested the possibility of a hypoxic induction pathway involving up-regulation of β-catenin by PI3K, be- cause this ... See full document
19
Enhancing T3 and cAMP responsive gene participation in the thermogenic regulation of fuel oxidation pathways
... metabólicos in silico mediante a identiicação dos elementos cis de regulação gênica responsivos ao T3 e cAMP (TREs, thyroid response elements e CREs, cAMP response elements), utilizando como referência o promotor ... See full document
9
Effects of androgen receptor and androgen on gene expression in prostate stromal fibroblasts and paracrine signaling to prostate cancer cells.
... WPMY-Vec and WPMY-AR cells were then profiled for overall gene expression patterns and for changes in these patterns associated with DHT treatment using a gene Chip ... See full document
11
Genes Regulating Maternal Recognition of Pregnancy in Domestic Animals: an Update
... adhesion and defence against invading ...domain, and are secreted from the cells by a nonclassical ...forms of galectins: galectin-1 (LGALS1), galectin-3 (LGALS3), Galectin-5 (LGALS5), ... See full document
10
SHBG is an important factor in stemness induction of cells by DHT in vitro and associated with poor clinical features of prostate carcinomas.
... the expression of AR in these cells as well, a finding well in line with the previous report (Bonaccorsi et ...upregulation of the stemness factors Oct3/4, Nanog, CD44 and ... See full document
12
Estrogenic Regulation of the SCF/c-KIT System in Prostate Cells: a Relationship with Prostate Cancer?
... Prostate cancer (PCa) is the most common type of oncological disorder in men, for which an increasing incidence has been ...Development and progression of PCa have been highly ... See full document
110
In search of epigenetic marks in testes and sperm cells of differentially fed boars.
... search of transmittable epigenetic marks we investigated gene expression in testes and sperm cells of differentially fed F0 boars from a three generation pig ... See full document
5
Selective alpha-particle mediated depletion of tumor vasculature with vascular normalization.
... safe and potent anti-tumor agents in mouse models of solid prostatic carcinoma, disseminated lymphoma, intra-perito- neal ovarian cancer and in a rat model of meningeal ... See full document
9
Int. braz j urol. vol.29 número5
... molecular mechanisms involved in oncogenesis and progression of prostate cancer ...construction of extensive DNA sequence data and gene ... See full document
11
Genetic variants in the MicroRNA biosynthetic pathway Gemin3 and Gemin4 are associated with a risk of cancer: a meta-analysis
... biogenesis of miRNAs, the Argonaute proteins (Ago1-4) along with Gemin3 and Gemin4 selectively bind to the guide strand to facilitate the formation of an miRNA- RNA-induced silencing complex (RISC) ... See full document
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