[PDF] Top 20 Genome-wide association study of pancreatic cancer in Japanese population.
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Genome-wide association study of pancreatic cancer in Japanese population.
... Institute of Medical Science, The University of Tokyo as well as National Cancer Center Hospital, ...consisted of Japanese volunteers that were obtained from Osaka-Midosuji Rotary Club, ... See full document
7
Genome wide association analysis of a founder population identified TAF3 as a gene for MCHC in humans.
... 5–10% of the total observed variance is explained by the genetic loci found to date, suggesting that additional loci should be searched using approaches alternative to large meta ...(Genome Wide ... See full document
8
Genome Wide Association Analysis Reveals New Production Trait Genes in a Male Duroc Population.
... this study, 796 male Duroc pigs were used to identify genomic regions controlling growth ...panel of 39,436 single nucleotide polymorphisms. In total, we detected 11 genome-wide and 162 ... See full document
15
Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation.
... characteristic of all glycan groups that showed association with HNF1a SNPs was the presence or absence of antennary fucose (Table ...expression of genes involved in the separates steps ... See full document
14
Use of genome-wide association studies for cancer research and drug repositioning.
... lack of clinical translation because of the size of the ...use of GWAS for drug repositioning, which is regarded as a promising strategy in translational ...medicine. In a ... See full document
13
Genome wide association studies for milk production traits in Chinese Holstein population.
... Genome-wide association studies (GWAS) based on high throughput SNP genotyping technologies open a broad avenue for exploring genes associated with milk production traits in dairy ...Taurus ... See full document
12
Joint effect of genetic and lifestyle risk factors on type 2 diabetes risk among Chinese men and women.
... GWAS Study (SDGS). The SDGS includes genome wide scan data of 1,019 diabetes cases and 1,710 ...Details of the study design have been described elsewhere ...cases in the ... See full document
7
Application of molecular information in sustainable animal breeding
... In genome-wide association or linkage disequilibrium studies, a population with thousands of individuals segregating for a trait of interest, or a diverse collection ... See full document
5
Evaluation of candidate nephropathy susceptibility genes in a genome-wide association study of African American diabetic kidney disease.
... improvements in coverage afforded through imputa- tion, this GWAS is not without ...to study design is the inclusion of 965 T2D-ESKD cases and 1029 population-based ...identified, in ... See full document
6
Efficiency of genome-wide association study in open-pollinated populations
... nested association mapping (NAM) populations (Bian et ...GWAS in open-pollinated populations was found in ...breakdown of LD in diverse maize lines, enabling very high resolution for ... See full document
59
Gene-centric characteristics of genome-wide association studies.
... to genome-wide association (GWA) studies to identify novel disease susceptibility single nucleotide polymorphisms ...high genome coverage and ascertain variants in genes, it is not ... See full document
8
Genome-wide association study identifies phospholipase C zeta 1 (PLCz1) as a stallion fertility locus in Hanoverian warmblood horses.
... total of 228 Hanoverian stallions were genotyped using the Equine SNP50 Beadchip (Illumina, San Diego, CA, USA) including 54,602 ...detect population structure was estimated using principal components ... See full document
12
Genetic determinants of cardiovascular events among women with migraine: a genome-wide association study.
... regression in PLINK [22] was used to investigate the association between gene variants and CVD events in the WGHS cohort and odds ratios (OR) and 95% confidence intervals (CI) were ...calculated. ... See full document
8
A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.
... Evaluation of the imputed data for the most significantly associated SNPs in our populations did not show association with COPD in ...absence of association to the COPD phenotype ... See full document
8
Genome-wide association study on the development of cross-reactive neutralizing antibodies in HIV-1 infected individuals.
... the population stratification test (n = 28), as described below were excluded, leaving 292 individuals for ...conducted in accordance with the ethical principles set out in the declaration of ... See full document
7
Accounting for Population Structure in Gene-by-Environment Interactions in Genome-Wide Association Studies Using Mixed Models.
... that population structure may cause serious effects on ...(eQTL) study of the human aortic endothelia cell collected by Romanoski et ...dataset of inbred mouse strains termed Hybrid Mouse ... See full document
19
Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links.
... novel association, metabomatching allowed the identification of the underlying ...illustrated in figure 2D, the pseudo-spectrum of rs281408 (lower half) closely resembles the NMR spectrum ... See full document
10
Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups.
... University of Duisburg-Essen, Essen, Germany, 2 Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Essen, Germany, 3 Centre National de la Recherche Scientifique (CNRS) ... See full document
10
Strong signature of natural selection within an FHIT intron implicated in prostate cancer risk.
... prostate cancer identified a locus of prostate cancer susceptibility at D3S1234 within the fragile histidine triad gene (FHIT), a tumor suppressor that induces ...Subsequent association tests ... See full document
8
Genome-Wide Association Study on Male Genital Shape and Size in Drosophila melanogaster.
... result of genotype–phenotype association analyses, we found 15 SNPs for PC1, 14 SNPs for PC2 and 15 SNPs for posterior lobe size with P-values smaller than 10 -5 (Figs 3, 4 & 5, S2, S3 & S4 ...plots ... See full document
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