[PDF] Top 20 Genome-wide associations of gene expression variation in humans.
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Genome-wide associations of gene expression variation in humans.
... affecting gene expression by genome-wide associa- tion ...such gene expression studies as well as for other studies that measure quantitative traits at the cellular ...basis ... See full document
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Genome-wide analysis of long noncoding RNA (lncRNA) expression in hepatoblastoma tissues.
... roles in cancer biology. We performed a genome-wide analysis of lncRNA expression in hepatoblastoma tissues to identify novel targets for further study of ...The ... See full document
9
Differential gene expression in liver tissues of streptozotocin-induced diabetic rats in response to resveratrol treatment.
... the genome-wide gene expression profile in strepto- zotocin induced diabetic rat liver tissues in response to resveratrol treatment and to estab- lish differentially expressed ... See full document
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Genome-wide delineation of natural variation for pod shatter resistance in Brassica napus.
... natural variation for shatter resistance in the ...lack of adequate genetic variability for breeding can be compensated for by introgressing genes from genetically diverse genotypes; this strategy ... See full document
13
Prediction of disease and phenotype associations from genome-wide association studies.
... [1,2]. In an effort to better understand the genetic basis of complex diseases, GWAS have been made technically feasible and affordable due to the completion of the Human Genome project [3,4], ... See full document
10
A novel method for identification and quantification of consistently differentially methylated regions.
... study of human tissues by using ICDMR, our results have shown to be similar to that obtained from the original study which used a supervised ...samples in a studied population, DMRs occur because of ... See full document
11
Functional annotation of rheumatoid arthritis and osteoarthritis associated genes by integrative genome-wide gene expression profiling analysis.
... annotation of these genes was performed based on gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis ...enriched in both RA and OA associated genes, such as ... See full document
9
Gene-centric characteristics of genome-wide association studies.
... enrichment of SNPs in ontologies and ...differential expression in pathway level [34], protein-protein interaction (PPI) analysis [35] and constructing PPI network ...analyze ... See full document
8
Genome-Wide Identification of the Invertase Gene Family in Populus.
... role in carbohydrate partitioning and plant development as it cataly- ses the irreversible hydrolysis of sucrose into glucose and ...family in plants is composed of two sub-families: acid ... See full document
21
Temporal dynamics of the developing lung transcriptome in three common inbred strains of laboratory mice reveals multiple stages of postnatal alveolar development
... study of genome-wide gene expression during normal lung development and maturation in three inbred laboratory strains of mice (A/J, C57BL/6J, and ...studies in the ... See full document
33
Genome-wide linkage analysis of global gene expression in loin muscle tissue identifies candidate genes in pigs.
... a genome-wide linkage analysis of global gene expression in a segregating swine ...studies of eQTL in pigs used a global expression array [9], but the ... See full document
11
Genome-wide analysis of nucleotide-level variation in commonly used Saccharomyces cerevisiae strains.
... used in laboratory experiments, some of which are distantly related to the sequenced reference strain ...this variation is important for interpreting biological results from experiments performed ... See full document
7
A genome-wide investigation of copy number variation in patients with sporadic brain arteriovenous malformation.
... rate of 78% between CNV states determined by qPCR and by PennCNV in 51 BAVM cases, including 23 called duplication and 28 called wildtype by ...rate of 52% between Birdsuite calls and qPCR (14 called ... See full document
9
Genome-wide patterns of genetic variation within and among alternative selective regimes.
... targets of differential selection. Much of the differentiation is likely the result of linkage ...effects. In the most extreme situation, there could be just one or two selected sites per ... See full document
15
Identification of new therapeutic targets by genome-wide analysis of gene expression in the ipsilateral cortex of aged rats after stroke.
... ligation of the middle cerebral artery in aged and young ...behaviour of major gene clusters after stroke. Overall, the pattern of gene expression strongly suggests that ... See full document
14
Replication of genome wide association studies of alcohol dependence: support for association with variation in ADH1C.
... evidence of association in the prior GWAS of alcohol dependence that we ...evidence of replication for rs13160562 (p = 0.03) in the ERAP1 gene that was first reported to be ... See full document
7
Genome-wide characterization of insertion and deletion variation in chicken using next generation sequencing.
... are of great importance for their ability to alter gene functions, especially those frameshifting INDELs locating in ...exons. In this study, lots of genes were affected by ... See full document
11
Tissue-specific effects of genetic and epigenetic variation on gene regulation and splicing.
... significant associations between DNA methylation and gene expression (expression Quantitative Trait Methylation, eQTMs; Table 1), and we ob- served that these associations were both ... See full document
25
Genome-wide prediction and functional validation of promoter motifs regulating gene expression in spore and infection stages of Phytophthora infestans.
... Because of such complications, Wasserman and Sandelin [39] posited the ‘‘futility theorem’’ which states that the great majority of predicted TFBSs lack function: it is thus futile to predict ... See full document
18
Integrative genome-wide gene expression profiling of clear cell renal cell carcinoma in Czech Republic and in the United States.
... with gene expression measurements obtained with previous microarray data, with approximately 60% (402) of downregulated and 74% (469) of upregulated genes from the discovery phase having been ... See full document
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